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XB-GENEPAGE-487698
Gene Symbol:
htra1
Gene Name: HtrA serine peptidase 1
Synonyms:
high temperature required A1
,
Xhtra1
,
prss11
,
xHtrA1
( Gene Function: serine protease Protein Function
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Serine protease with a variety of targets, including extracellular matrix proteins and proteoglycans such as biglycan, syndecan-4 and glypican-4. Through cleavage of proteoglycans, may release soluble ...[+]
Interactants:
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Diseases: Disease Ontology:
age related macular degeneration 7
OMIM:
MACULAR DEGENERATION, AGE-RELATED, 7; ARMD7
External Links:
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Xenbase Gene ID | XB-GENE-487699 | XB-GENE-17330113 | XB-GENE-865727 | |||||
Gene Symbol | htra1 | htra1.L | htra1.S | Chromosome | Chr7 | chr7L | chr7S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
780187
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108696094
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496061
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mRNA |
RefSeq
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | htra1 | htra1.L | htra1.S | |||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Exploration of the extracellular space by a large-scale secretion screen in the early Xenopus embryo., Int J Dev Biol 2005 ![]() |
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Most Recent |
The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation., Development 2015 ![]() |
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All | View All Papers 2 paper(s) referencing morpholinos | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 21 terms | 4 terms | 6 terms | |||||
PANTHER | htra1 | |||||||
KEGG Pathways | K08784 | K08784 | K08784 | |||||
KOG |
[O] Serine protease
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | htra1 | |||||||
Morpholinos (on-target & off-target) | htra1 MO1 | htra1 MO1 | htra1 MO1 | |||||
ORFs | htra1 ORF1 , htra1 ORF2 | htra1.S ORF1 | ||||||
Clones | Horizon Source BioScience | Horizon | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



