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Summary Expression Gene Literature (6) GO Terms (21) Nucleotides (139) Proteins (40) Interactants (322) Wiki
XB-GENEPAGE-487698
Gene Symbol:
htra1

Gene Name:
HtrA serine peptidase 1

Synonyms:
high temperature required A1 , Xhtra1 , prss11 , xHtrA1 ( Add synonyms , Nomenclature history )

Gene Function:
serine protease

Protein Function :
Serine protease with a variety of targets, including extracellular matrix proteins and proteoglycans such as biglycan, syndecan-4 and glypican-4. Through cleavage of proteoglycans, may release soluble ...[+]


InterPro :
GPCR Rhodpsn 7TM , Olfact rcpt , GPCR Rhodpsn , Kazal dom sf [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
age related macular degeneration 7 [+]

OMIM:
MACULAR DEGENERATION, AGE-RELATED, 7; ARMD7 [+]

External Links:
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Xenbase Gene ID XB-GENE-487699 XB-GENE-17330113 XB-GENE-865727
Gene Symbol htra1 htra1.L htra1.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 780187
108696094
496061
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein TrEMBL RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine htra1 htra1.L htra1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards HTRA1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Htra1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Htra1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR htra1a htra1b ZFIN Ensembl
chicken
GEISHA HTRA1 Ensembl
fruit fly
worm
Publications
First Exploration of the extracellular space by a large-scale secretion screen in the early Xenopus embryo., Int J Dev Biol 2005                                    
Most Recent The serpin PN1 is a feedback regulator of FGF signaling in germ layer and primary axis formation., Development 2015                                      
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 21 terms 4 terms 6 terms
PANTHER htra1
KEGG Pathways K08784 K08784 K08784
KOG [O] Serine protease
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks htra1
Morpholinos (on-target & off-target) htra1 MO1 htra1 MO1 htra1 MO1
ORFs htra1 ORF1 , htra1 ORF2 htra1.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info