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Summary Expression Gene Literature (3) GO Terms (10) Nucleotides (358) Proteins (40) Interactants (117) Wiki
XB-GENEPAGE-491570
Gene Symbol:
arpc2

Gene Name:
actin related protein 2/3 complex subunit 2

Synonyms:
mgc69338 ( Add synonyms , Nomenclature history )

Gene Function:
control of actin polymerization

Protein Function :
Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:17178911). The Arp2/3 complex medi...[+]


InterPro :
ARPC2/4 , ARPC2

Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-491571 XB-GENE-866076 XB-GENE-17346100
Gene Symbol arpc2 arpc2.L arpc2.S
Chromosome scaffold_131 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 448094
779406
432109
mRNA RefSeq RefSeq RefSeq
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein RefSeq
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine arpc2 arpc2.L arpc2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ARPC2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Arpc2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Arpc2 Ensembl
zebrafish
ZFIN, AGR arpc2 ZFIN Ensembl
chicken
GEISHA ARPC2 Ensembl
fruit fly
FLYBASE Arpc2 Ensembl
worm
Publications
First Nuclear ARP2/3 drives DNA break clustering for homology-directed repair., Nature 2018                                
Most Recent Grp94 Regulates the Recruitment of Aneural AChR Clusters for the Assembly of Postsynaptic Specializations by Modulating ADF/Cofilin Activity and Turnover., eNeuro 2020  
All View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 7 terms 8 terms 8 terms
PANTHER arpc2
KEGG Pathways K05758 K05758 K05758
KOG [Z] Actin-related protein Arp2/3 complex, subunit ARPC2
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks arpc2
Antibodies Arpc2 Ab1 Arpc2 Ab1 Arpc2 Ab1
ORFs arpc2 ORF1 arpc2.L ORF1 MGC78865 ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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