Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (20) GO Terms (35) Nucleotides (14281) Proteins (47) Interactants (648) Wiki
XB-GENEPAGE-492780
Gene Symbol:
cirbp

Gene Name:
cold inducible RNA binding protein

Synonyms:
Xcirp , cirp , cirbp-a , cirp1 , cirbp-b , cirbp2 , xCIRP2 , CIRP2 ( Add synonyms , Nomenclature history )

Gene Function:
cytoplasmic RNA-binding protein

Protein Function :
Cold-inducible mRNA binding protein. Acts cooperatively with elavl1/elrA to stabilize AU-rich element (ARE)-containing mRNAs by binding to them and inhibiting their deadenylation. Essential for embryon...[+]



Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-492781 XB-GENE-6256647 XB-GENE-492785
Gene Symbol cirbp cirbp.L cirbp.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 549982
379761
379484
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq RefSeq Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine cirbp cirbp.L cirbp.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards CIRBP OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Cirbp MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Cirbp Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR cirbpb cirbpa ZFIN Ensembl
chicken
GEISHA RBM3 Ensembl
fruit fly
worm
Publications
First XCIRP (Xenopus homolog of cold-inducible RNA-binding protein) is expressed transiently in developing pronephros and neural tissue., Gene 1998            
Most Recent Asymmetric distribution of biomolecules of maternal origin in the Xenopus laevis egg and their impact on the developmental plan., Sci Rep 2018  
All View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 31 terms 23 terms 17 terms
PANTHER cirbp
KEGG Pathways K13195 K13195 K13195
KOG [A] Alternative splicing factor SRp20/9G8 (RRM superfamily)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks cirbp
Antibodies Cirbp Ab1 Cirbp Ab1 Cirbp Ab1
Morpholinos cirbp MO1 , cirbp MO2 , cirbp MO3 cirbp MO1 , cirbp MO2 , cirbp MO3 cirbp MO1 , cirbp MO2 , cirbp MO3
ORFs cirbp.L ORF1 cirbp.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556