Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (11) GO Terms (4) Nucleotides (181) Proteins (56) Interactants (91) Wiki
XB-GENEPAGE-492849
Gene Symbol:
shf

Gene Name:
Src homology 2 domain containing F

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
Adaptor protein GRB2, contains SH2 and SH3 domains

Protein Function :


InterPro :
SHF SH2 , SH2 dom sf , SHF , SH2 [+]

Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-492850 XB-GENE-17330359 XB-GENE-6488510
Gene Symbol shf shf.L shf.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100216125
108711341
108712956
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine shf shf.L shf.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SHF OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Shf MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Shf Ensembl
zebrafish
chicken
GEISHA SHF Ensembl
fruit fly
FLYBASE shf Ensembl
worm
Publications
First Distinct effectors of platelet-derived growth factor receptor-alpha signaling are required for cell survival during embryogenesis., Proc Natl Acad Sci U S A 2005            
Most Recent FoxN3 is necessary for the development of the interatrial septum, the ventricular trabeculae and the muscles at the head/trunk interface in the African clawed frog, Xenopus laevis (Lissamphibia: Anura: Pipidae)., Dev Dyn 2019            
All View All Papers 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 4 terms 0 term 0 term
PANTHER shf
KEGG Pathways K23697 K23697
KOG [T] Adaptor protein GRB2, contains SH2 and SH3 domains
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks shf
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info