edem1 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Gene Literature (0)

Nucleotides (338)

Interactants (0)

XB-GENEPAGE-492907

Gene Symbol: edem1 Gene Name: ER degradation enhancer, mannosidase alpha-like 1 Synonyms: mgc76118 Add Xenopus synonyms Gene Function: glycosyl hydrolase Interactants:

XB-GENE-492908

XB-GENE-866212

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_204066\|Xenopus (Silurana) tropicalis ER degradation enhancer, mannosidase alpha-like 1 (edem1), mRNA GACAGGCTTGCGGCGATGGCCTATCAGAATGCGTGGGGGAGTCCGACCCGGAAGTGGCGGCCCTGGGATGCGGTGGTGCTCTGTGCTGCTGGGGCTGCTGCTTCTGCGGCTTGGGCTACACGCTCTGCGGGGTCTTATCCTGCCCGGAACGTCTCCTGTAGTGGTGCCGGGAGTCCATGCTGTGTGCCGAGCCTCGTATGGCCGCTTTGTCCTGGGAGCCGGGGATGAGTACGGCCGCCGCTACAGCTCTTTCCCTGAGGGGCTGCGGAAAGAAATGCGGGAGATGGCCCGTGGGATGTTCTCATTCGGCTATGACAGCTACATGAAGTACGCCTTTCCCGAGGATGAGCTCAACCCCATCCTGTGCCGGGGACGCGGGCCAGACCACGGAGACCCTTCAAATCTAAACATCAATGATGTCCTTGGGAATTACTCCCTAACCCTGATTGATGCACTGGACACTTTAGCGGTGATGGGCAATGCCACTGAGTTTCACAGAGCTGTTCGCTTGGTGATTGACACAGTTTCCTTTGATAAGAATTCAACGGTGCAAGTGTTTGAGGCTACTATTCGGATTCTAGGCAGCTTACTGTCAGCCCACATAATCCTAACGGACAGCAAGCAGCCTTTTGGCAACATGACACTAAGTGGTTATGATAATGAACTTCTTCATATGGCTCGTGACCTCGCAGTTAGACTTCTGCCTGCGTTTGAGAACACCAAGACAGGCATGCCTTATCCCAGGGTTAATCTGAAGAAGGGGGTCCCTCCAGATAGCAGAAATGAGACCTGCACTGCCGGGGCCGGTTCACTGCTTGTGGAGTTTGGAATCCTAAGTCGGCTTTTGGGGGACTCCACGTTTGAGTGGGTTGCTCGCCGGGCTGTCAGAGCCCTCTGGAGTTTACGAAGCAATGATACCGGCCTCCTTGGAAACGTGGTGAACATACAGACTGGGCAGTGGGTTGGAAAACAAAGCGGCCTGGGAGCTGGGTTGGACTCATTCTTTGAATATTTGCTCAAGTCTCACATCCTGTTTGGAGAGGAAGAGGATTTGGAAATGTTTAATGAGGCTTACAAGAGTATCCAGAACCACCTACGCAGGGGGCGTGAAGCATGTAATGAAGGAGAGGGGGACCCGCCATTGTATGTGAATGTTAATATGCTTAATGGTCAGCTCATGAACACTTGGATTGACTCGCTGCAGGCTTTCTTCCCCGGGCTGCAGGTCTTAAAGGGAGATATTGAGGATGCCATTTGCCTGCATGCTTTTTATTATGCCATTTGGAAGCGATATGGAGCTTTACCTGAACGATACAACTGGCAACTACAGGCCCCTGATGTCTCCTTCTACCCTCTCAGGCCAGAGTTGGTAGAGTCCACATATCTTTTATACCAGGCCACCAAGAACCCCTTCTATCTGCATGTGGGAATGGATATTCTGTTGAGCCTGGAGAAGCATGCTAAGGCCAAGTGTGGATATGCAACTTTACACCATGTTGTGGACAAATCTCAGGAGGATCGGATGGAGAGCTTCTTCCTGAGTGAAACTTGCAAATACCTCTACCTGCTGTTTGATGAGGATAATCCGCTGCATCGGGTTGATAATAAGTACCTTTTCACCACTGAGGGCCACCTGATCCCACTTGACCCGCGTTTGAGGGACACTTCATGGCAGGACATCTTCCATAATAAAAACAAAGTGCAGCAAACCCAGGAGAAACTGTCACAGACAAAGCTCAGAACTGCTAACTCCAGCACAAATTGTTATAAGGTTCCGGAAGAGCGCAGGTTTTCACTACCGCTGAAGAGTGTCTACATGCGCCAGATTGACCAGATGGTTGGGCTGTTGTAACTCATGGTGCAACCTTATGTGGATCAAGGAATGCAGCTATTTAGGAACAAGGTTCTTCCCCATATGACTGGAATATCTGCTGGAGGCTGTGCGGAGTTCCTGTGTGCATACCCTCAGCATGCAAGGCAATAATGGTGATTGTGGCATGTCTGGGTGCACAGAAGAATCTGCTCCTTGTCTATTATGCAATATTGCACAAAATGTTTTGGGATGCTCCACATATAGCAAACCCTCAGGGATTTTGAAGGAATATACACCCTAGTATGTGTCTTCCAAAGCTGCTCTTGTTCCTCAACACCTTCCCCACGGCAGGACCAATACAAAAGCAGATTCCTCATTGGCTGCTGATGAGACAATTCTCAGTATCTCCTAGCAAACCAAGGTCTCTGCAGAGGAATGGCTCTGCCAGGTGCATATTGTTGCCCGTTTGCTGCTTTGTGACTATGGACAGTCCCTGTAGTCAAGTTACAGTTTGCCAAAATAGTGTCTTAAGCCAATCGTATTGTTCAGATTGTGGCCTTGAAACTACGACTTGGACAGTGCTTTCCTCTTGCTCATGCAGCTTCCTTTGATGGATCAGTGCCTTAAAACGACTCATTGTCTTTCATTTTCCAGCAAAGGTCGGTGACACCCGCTCCTCAGCCACTCAGCACCGTGCAGATGAATACGTTACTCTTTTATTAGTTTCCTAATCAGGGCTTCTTTTTAATAATTTTGTGGGGGTTTTTTTAAGGATGAGGAATTCCGTATTTTCGAAGTCTGAGGAACAAACTGAACCAACACAAGTTATAATGTGTACTAATGTTTGCTGGGCATTGAGCCCCTTGCTGTTAGTTTGCACGCGCTGCAGACTTGTGGTGGGAGGAGTATTGAGATGTTATGATCAGTGCTATGCCAGGTGTAATTGTAATTGTTAAAAACATTCAGGGATTATTTTATAAACTGTAAGACTGAAAATGTGAGTTTTTTTTTAATGTAAAGTCGGAGTCTTATTAAAAATCTGCAATTTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGGGCGGCAAGCATTTTCAGAGATTAAATGGGCCTTTTCTACTTGAGACAATTCGGATGTCTGCTGTTCTTGGGTGTGCACGTTCAGTGGGTTTCATCAGAGGTTTTCCCCACAGAAAACCCTCTAGGTTATGACTGTTCGCATATCTGGGAAAGAAACAATGAATCTGTCAGTGGGATTTACACAATAAAACCTCTAGGTGCCAGCACATCTTTTCAGGTTTTCTGTGAAATGAAAGCTGATGGGGGCTGGACACTCATACAGAGACATGACGGACAAGATGGCCTTCTCTTCACTAGAACCTGGGCTGAATACAAACTAGGATTTGGAAACATCTCTGGAGAACACTGGTTGGGACTGGAAAACATGCATATACTGACTAACCAGGATAGCAGAGCCTCAGAACTGTTCATCAGCCTTGAGGCCTTTGATGATAGTGATGGAGCCTTCGCCTTGTACAGCTCATTCATAGTTGCTCCTGAAAGCAAATTATACCAGCTCTCTGTGGGAAATTATTCTGGAAACGCAGGAGATGCTTTTAGAACTGGAAACAACAATCAAGATGGCAACTTTTTTACCACCAAAGATAAGGACAATGACAAGTGCAATCCATGTAAGATTGGTGACACCAGGTTTTCAAGTTGCAGCCGTTATCAGTCTAGTTCTGGATGGTGGTTTAGCAGCTGCGGCAATGCAAATCTGAATGGTCAGTGGCGCCCTGAAGAAAATAACGTGGGCTGGGCCTCTTCAGTGCACTGGGGGTCATACAGAGCCACGGAATCACTGAAATACAGCAAGATGTTTGTTAGAAATTATTGATCCATTTTCTGGCTGTATCTTTGTAAATAGTTCTAAACATGCACAACAGGGATACCTCCTGCAACTCTAAATATTTGATATTTTGAAAGGATTATTGCAGTATTTTGATTACCTCAGATATCTTTTGTGGGTTTTTTTTTAATTTAGTCACTTAAATGAAAACTATACCTTCAGAATAAATAATGAACCAACATATAATCAATATCATAACAAGGGACATCTTAAATATTTATCAAGTTGGCAGTCAAATTTGGCCTTGTATAACTTGAGCCAACATTCTGTAATGTTCTTAGTGTCACTCATTGAAATATGTAGGTTCTAACTGGAACAGGAATGAGCCCAAGTGGAAAAGACACAGCTCTGTCCATTCATTGGCTGACATCCTAGCATGTATAAGTGCCTTTGGTTGTGTGCCCACAGGGTAGTAGTTACAATTGCATTTTCTATATGGGATTATCTAGTGGTACACACTACTAGAAAAATATATTTTCCATGAAAAGGCTTTATTTATATAAAACAATGTTTTACATATGGATTGTTTTATGTGATATATTTGTAAAGAGACCTATAGTGTTCAAGGGCATAGGTGCCCATTAAATATATCTGTGCTAATAAGGAACATTCTCTCACACAAGACAGAGAATACAGCAAACATCTGATAGAATATGCCGTACAGCTGTAAATAGTTTATTAGATGCTTGTTGTATCTGTTTTCTTTTTTATTTCTATTAATGTGTTTTTTTAATTAACTTTTTATACGTTATTGTATTCACTGAACACTTGAATAAATGAACAAAAGAAAAAAAAAAAAAAAAAAA	Refseq >NM_001097971\|Xenopus laevis ER degradation enhancer, mannosidase alpha-like 1 (edem1), mRNA CGGAAGTGGTGGCCCTGTAATGCGGTGGTGTTCTGCCCTGCTGGGGCTGCTGCTTCTCCGGCTCGGGCTGCAAGCTCTGCGGGGTCTTGTCCTGCCTGGGACAACTCCTGTAGTGATACCGGGAGTCAATGCCGTGTGCCGCGCCTCTTATGGCCGTTTTGTCCTGGGAGCCGGAGATGAGTACGGCCGCCGCTACAGCTCTTTCCCCGCGGGGCTGCGTAAAGAAATGCGTGAGATGGCCCGCGGCATGTTCTCGTTCGGCTATGACAACTACATGAAGTATGCCTTCCCTGAGGATGAGCTCAATCCCATTCTCTGCCGGGGACGTGGACCAGACCACGGAGACCCTTCAAATCTAAACATCAATGATGTCCTTGGAAACTACTCCCTAACCCTGATTGATGCACTGGACACTTTAGCGGTGATGGGCAATGCCACAGAGTTTCACAGAGCTGTTCGATTGGTGATCGATACCGTTTCCTTTGACAAGAATTCAACAGTGCAAGTGTTTGAGGCTACTATTCGAATTCTAGGCAGCTTACTGTCAGCCCACATAATCCTGACCGACACCAAGCAGCCCTTTGGCAACATGACTCTAAGTGACTACGATAATGAACTTCTTCATATGGCTCATGACCTTGCAGTTAGACTTCTGCCTGCATTTGAGAACACCAAAACAGGGATGCCTTATCCTAGGGTTAATCTGAAGAAGGGAGTCCCCCCAGATAGTAGAAATGAGACCTGCACTGCCGGAGCTGGCTCCCTGCTTGTGGAGTTTGGAATTCTAAGTCGGCTTTTAGGGGATTCCACGTTTGAGTGGGTTGCTCGCCGTGCTGTCAGAGCACTCTGGAGTTTGCGAAGCAACAACACCGGCCTCCTTGGGAATGTGGTGAACATACAGACTGGACAGTGGGTTGGAAAACAAAGTGGCCTGGGTGCTGGGTTGGACTCCTTTTATGAATATTTGCTCAAGTCCTACATCCTGTTTGGAGAGGAAGAGGACTTGGAAATGTTTAACGAGGCTTACAAAAGTATCCAGAACCACCTTCGCAGGGGGCGTGAAGCATGTAATGAAGGAGAAGGGGACCCGCCATTGTATGTGAATGTTAACATGCTTAATGGTCAACTCATGAACACATGGATTGACTCACTGCAGGCTTTCTTCCCGGGACTACAGGTCCTAAAGGGAGATATTGAGGATGCGATTTGCCTGCATGCATTTTATTATGCCATTTGGAAACGCTATGGAGCTTTACCTGAACGATACAACTGGCAACTGCAGGCCCCTGATGTCTCCTTTTACCCTCTCAGGCCAGAGCTGGTAGAGTCCACGTATCTTTTATACCAGGCCACTAAGAACCCCTTCTATCTGCACGTGGGTATGGATATTCTGTTGAGTCTGGAGAAGCATGCTAAAGCCAACAGGTGTGGATATGCAACTATACACCATGTTGTGGACAAGTCACAGGAGGATAGGATGGAAAGCTTCTTCCTGAGTGAAACTTGCAAATACCTCTACCTGCTGTTTGATGAGGATAACCCACTGCATCGGGTTGATAATAAATACCTGTTCACCACCGAGGGCCATCTGATCCCACTCGACCCTCGTTTGAGGGACACATCATGGCAGGACATCTTTCATCGTAAAAGCAAAGTGCCGCAAACCCAGGACAAACTGTCACAGACCAAGCTCCGAACTGGTAACTCCAGCTCAAATTGTTATAGGGTTCCAGAAGAGCGTAGGTTTTCACTACCGCTGAAAAGTGTCTACATGCGCCAGATTGACCAGATGGTTGGGCTTTTGTAGTTTATAGTCGGACCTGCTTGTGGATTAAGGAATCTTATCTATTCAGCAACAAGACATCAGGTTCTCCCACATGTAACTGGAATCTGTGCTGGAGGCTGTGCAGATACCCTGTCTGCATTCAGTGCAAACGTGGTGATCAGGGCAGGCTTGGGTGCTCAGAAGAATCTGCTCCGTGTCTATTATGCAATATTGCACAATTTTTTTTGGGATGCTCTGTGTATGGCAAACCCTCAGGGATTTTGAAAGACTATACACTTATGTGTCTTCCAAAGCTACTCTTGTTCCTCAATACCTTCCCCACGTCAGGACCAATACAAAAGCAGATTCCTCATTGGCTGCTGATAAAACAATGTTCACAATCACCTAGCAAACCAAGGATTCTGCAGAGGAATGAGTTGCTCCCTTGCTGCTTTGTGACTAGGGACAGTCCCCATAGTCAAGTTACATTTTGCCAAAATAGTGTCTTAAGCCAATTTTATTGTCCGGATTGTGGCCTTGAAACTACAACTTGGACAGCCTTTTCACCTTACTCATACCATGTCTCTCTGCAACTTCTTTTTATTGGACCAGTGCCTTAAATAGATTTTTCTTTCTTTTTCCAGCAAAGGTCAGTGACACTTGCTCCTCATCCACTCAGCACCTTGCAAATAAATACATTACTCTTTTTACCCGTCTTCTAATCAGGGCTTATTTTTAATCATTTTGTTTGGATGTGGAATTCCGTATTTTTGAAGTCTAAGGAACAAATGGAACCAACACAAGTTATTACGTGTGCCAATGTCTGCTGGTCACTGACCCTGTTAGACTTGGGCGAGCGTTGAGACTATGGGCACGCTTCTGTGAACTGCCTGCCCTGCAGCACGATCAATGCCAGGTGTAATCACTGTTAAGAAAAATACATTCAGGGATTATTTTATAAAATTGTAAGATTTGATAATGTGATTTTTTTTTTTAATGTAAGGTCAGAGTCTTATTAAAAATCTGCAATTTCAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_989397\|ER degradation enhancer, mannosidase alpha-like 1 precursor [Xenopus (Silurana) tropicalis] MRWCSVLLGLLLLRLGLHALRGLILPGTSPVVVPGVHAVCRASYGRFVLGAGDEYGRRYSSFPEGLRKEMREMARGMFSFGYDSYMKYAFPEDELNPILCRGRGPDHGDPSNLNINDVLGNYSLTLIDALDTLAVMGNATEFHRAVRLVIDTVSFDKNSTVQVFEATIRILGSLLSAHIILTDSKQPFGNMTLSGYDNELLHMARDLAVRLLPAFENTKTGMPYPRVNLKKGVPPDSRNETCTAGAGSLLVEFGILSRLLGDSTFEWVARRAVRALWSLRSNDTGLLGNVVNIQTGQWVGKQSGLGAGLDSFFEYLLKSHILFGEEEDLEMFNEAYKSIQNHLRRGREACNEGEGDPPLYVNVNMLNGQLMNTWIDSLQAFFPGLQVLKGDIEDAICLHAFYYAIWKRYGALPERYNWQLQAPDVSFYPLRPELVESTYLLYQATKNPFYLHVGMDILLSLEKHAKAKCGYATLHHVVDKSQEDRMESFFLSETCKYLYLLFDEDNPLHRVDNKYLFTTEGHLIPLDPRLRDTSWQDIFHNKNKVQQTQEKLSQTKLRTANSSTNCYKVPEERRFSLPLKSVYMRQIDQMVGLL	Refseq >NP_001091440\|ER degradation enhancer, mannosidase alpha-like 1 precursor [Xenopus laevis] MRWCSALLGLLLLRLGLQALRGLVLPGTTPVVIPGVNAVCRASYGRFVLGAGDEYGRRYSSFPAGLRKEMREMARGMFSFGYDNYMKYAFPEDELNPILCRGRGPDHGDPSNLNINDVLGNYSLTLIDALDTLAVMGNATEFHRAVRLVIDTVSFDKNSTVQVFEATIRILGSLLSAHIILTDTKQPFGNMTLSDYDNELLHMAHDLAVRLLPAFENTKTGMPYPRVNLKKGVPPDSRNETCTAGAGSLLVEFGILSRLLGDSTFEWVARRAVRALWSLRSNNTGLLGNVVNIQTGQWVGKQSGLGAGLDSFYEYLLKSYILFGEEEDLEMFNEAYKSIQNHLRRGREACNEGEGDPPLYVNVNMLNGQLMNTWIDSLQAFFPGLQVLKGDIEDAICLHAFYYAIWKRYGALPERYNWQLQAPDVSFYPLRPELVESTYLLYQATKNPFYLHVGMDILLSLEKHAKANRCGYATIHHVVDKSQEDRMESFFLSETCKYLYLLFDEDNPLHRVDNKYLFTTEGHLIPLDPRLRDTSWQDIFHRKSKVPQTQDKLSQTKLRTGNSSSNCYRVPEERRFSLPLKSVYMRQIDQMVGLL

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.8768 [+] Str.47431	Xl.53315
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	EDEM1
mouse		MGI	Edem1	All(3) Targeted, knock Out(1)
zebrafish		ZFIN	edem1	1 Lines(s)

Publications
First:
Most recent:
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Functional Ontologies
GO: Molecular:		amylase activity calcium ion binding fucosidase activity More[+] galactosidase activity glucosidase activity hexosaminidase activity hydrolase activity, hydrolyzing O-glycosyl compounds lytic transglycosylase activity mannosidase activity mannosyl-oligosaccharide 1,2-alpha-mannosidase activity mannosyl-oligosaccharide mannosidase activity trehalase activity
Biological:		protein amino acid N-linked glycosylation
Cellular Component:		membrane
EC:		Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds
KOG:		[G] Glycosyl hydrolase, family 47

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.8768.1.S1_at [+] Str.47431.1.A1_at	Xl.3947.1.A1_at
Affymetrix 2.0			Xl2.53315.1.S1_at [+] Xl2.53315.2.A1_at Xl2.3947.2.S1_at Xl2.3947.1.A1_at

Symbol legend[+]