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Summary Expression Gene Literature (13) GO Terms (13) Nucleotides (108) Proteins (31) Interactants (214) Wiki
XB-GENEPAGE-494861
Gene Symbol:
shc1

Gene Name:
SHC (Src homology 2 domain containing) transforming protein 1

Synonyms:
mgc98812 , shc ( Add synonyms , Nomenclature history )

Gene Function:
Adaptor protein SHC and related proteins

Protein Function :
Implicated in ras-dependent oocyte maturation induced by insulin/IGF-1.



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-494862 XB-GENE-494866 XB-GENE-17333961
Gene Symbol shc1 shc1.L shc1.S
Chromosome Chr08 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 8.0 Version 9.1 Version 9.1
CDS Gene model Gene model
Entrez Gene 100492349
399198
108700442
mRNA NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine shc1 shc1.L shc1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SHC1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Shc1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Shc1 Ensembl
zebrafish
ZFIN, AGR shc1 ZFIN Ensembl
chicken
GEISHA SHC1 Ensembl
fruit fly
worm
Publications
First SIP/SHIP inhibits Xenopus oocyte maturation induced by insulin and phosphatidylinositol 3-kinase., Mol Cell Biol 1997  
Most Recent SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue., PLoS Pathog 2018                      
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 11 terms 5 terms 6 terms
PANTHER shc1
KEGG Pathways K06279 K06279
KOG [T] Adaptor protein SHC and related proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks
ORFs shc1.L ORF1
Clones Horizon Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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