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Summary Expression Gene Literature (42) GO Terms (13) Nucleotides (614) Proteins (27) Interactants (266) Wiki
XB-GENEPAGE-494930
Gene Symbol: des.1

Gene Name: desmin, gene 1

Synonyms: desm , csm1 , csm2 , cmd1l , des.1-b , des.1-a ( Add synonyms , Nomenclature history )

Gene Function: intermediate filament

Protein Function :
Muscle-specific type III intermediate filament essential for proper muscular structure and function. Plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and fo...[+]

Interactants: Loading ...
Disease Ontology: myofibrillar myopathy 1 [+]

OMIM Diseases: CARDIOMYOPATHY, DILATED, 1I; CMD1I [+]

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Xenbase Gene ID XB-GENE-494931 XB-GENE-494935 XB-GENE-6254678
Gene Symbol des.1 des.1.L des.1.S
Chromosome Chr09 chr9_10L chr9_10S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene: 394739
Entrez Gene: 446868
Entrez Gene: 379869
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL RefSeq TrEMBL RefSeq TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine des.1 des.1.L des.1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards DES OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Des MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR desma ZFIN Ensembl
chicken
GEISHA DES Ensembl
fruit fly
worm
WORMBASE
Publications
First Tetanic hyperpolarization of single medullated nerve fibers in sodium and lithium., Am J Physiol 1976  
Most Recent Xenopus SOX5 enhances myogenic transcription indirectly through transrepression., Dev Biol 2018                      
All View All Papers 2 paper(s) referencing morpholinos 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 9 terms 2 terms 7 terms
PANTHER des.1
KEGG Pathways K07610 K07610 K07610
KOG [DY] Nuclear envelope protein lamin, intermediate filament superfamily
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon
Antibody Des.1 Ab1 Des.1 Ab1 Des.1 Ab1
ORF des.1 ORF1 des.1.L ORF1 des.1.S ORF1
Affymetrix 1.0 Str.5047.1.S2_at [+] Xl.2665.1.S1_at [+]
Affymetrix 2.0 Xl2.29616.1.S1_at Xl2.2665.1.S1_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.12.1


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