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Summary Expression Gene Literature (2) GO Terms (19) Nucleotides (112) Proteins (39) Interactants (109) Wiki
XB-GENEPAGE-5757511
Gene Symbol:
hace1

Gene Name:
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
ubiquitin-protein ligase

Protein Function :
E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab p...[+]



Interactants:
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Diseases: 


OMIM:
SPASTIC PARAPLEGIA AND PSYCHOMOTOR RETARDATION WITH OR WITHOUT SEIZURES; SPPRS

External Links:
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Xenbase Gene ID XB-GENE-5757512 XB-GENE-5757545 XB-GENE-17345428
Gene Symbol hace1 hace1.L hace1.S
Chromosome Chr5 chr5L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 734146
446912
mRNA RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine hace1 hace1.L hace1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards HACE1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Hace1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Hace1 Ensembl
zebrafish
ZFIN, AGR hace1 ZFIN Ensembl
chicken
GEISHA HACE1 Ensembl
fruit fly
worm
Publications
First The E3 ubiquitin ligase Hace1 is required for early embryonic development in Xenopus laevis., BMC Dev Biol 2016                      
Most Recent miR-199 plays both positive and negative regulatory roles in Xenopus eye development., Genesis 2020                          
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 18 terms 13 terms 0 term
PANTHER hace1
KEGG Pathways K12166 K12166
KOG [OK] E3 ubiquitin-protein ligase/Putative upstream regulatory element binding protein
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks hace1
Morpholinos (on-target & off-target) hace1 MO1 hace1 MO1 , hace1 MO3
ORFs hace1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info