Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (25) GO Terms (21) Nucleotides (226) Proteins (41) Interactants (73) Wiki
XB-GENEPAGE-5788003
Gene Symbol:
lig3

Gene Name:
ligase III, DNA, ATP-dependent

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
DNA ligase

Protein Function :


InterPro :
Pro 4 hyd alph , EF hand dom , EF-hand-dom pair , EF Hand 1 Ca BS [+]

Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-5788004 XB-GENE-5788023 XB-GENE-17332260
Gene Symbol lig3 lig3.L lig3.S
Chromosome Chr10 chr9_10L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 549105
398275
mRNA RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine lig3 lig3.L lig3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards LIG3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Lig3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Lig3 Ensembl
zebrafish
ZFIN, AGR lig3 ZFIN Ensembl
chicken
GEISHA LIG3 Ensembl
fruit fly
FLYBASE DNAlig3 Ensembl
worm
Publications
First ATM mediates oxidative stress-induced dephosphorylation of DNA ligase IIIalpha., Nucleic Acids Res 2006                
Most Recent Single-Nucleotide Polymorphisms of Genes Involved in Repair of Oxidative DNA Damage and the Risk of Recurrent Depressive Disorder., Med Sci Monit 2016  
All View All Papers 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 21 terms 9 terms 0 term
PANTHER lig3
KEGG Pathways K10776 K10776
KOG [L] ATP-dependent DNA ligase III
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks lig3
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info