Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (0) GO Terms (19) Nucleotides (120) Proteins (31) Interactants (27) Wiki
XB-GENEPAGE-5812884
Gene Symbol:
brcc3

Gene Name:
BRCA1/BRCA2-containing complex subunit 3

Synonyms:
brcc36 ( Add synonyms , Nomenclature history )

Gene Function:
26S proteasome regulatory complex, subunit RPN11

Protein Function :
Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not have activity toward 'Lys-48'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that spec...[+]



Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-5812885 XB-GENE-5812935 XB-GENE-17340506
Gene Symbol brcc3 brcc3.L brcc3.S
Chromosome Chr08 chr8L
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 549211
447688
mRNA RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine brcc3 brcc3.L brcc3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards BRCC3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Brcc3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Brcc3 Ensembl
zebrafish
brcc3 Ensembl
chicken
GEISHA BRCC3 Ensembl
fruit fly
worm
Publications
First
Most Recent
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 19 terms 19 terms 0 term
PANTHER brcc3
KEGG Pathways K11864 K11864
KOG [O] 26S proteasome regulatory complex, subunit RPN11
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks brcc3
ORFs brcc3 ORF1 brcc3.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556