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Summary Expression Gene Literature (29) GO Terms (10) Nucleotides (86) Proteins (28) Interactants (97) Wiki
XB-GENEPAGE-5817034
Gene Symbol:
kcnq4

Gene Name:
potassium channel, voltage gated KQT-like subfamily Q, member 4

Synonyms:
kv7.4 , k(v)7.4 ( Add synonyms , Nomenclature history )

Gene Function:
voltage-gated potassium channel activity

Protein Function :



Interactants:
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Diseases: 


Disease Ontology:
autosomal dominant nonsyndromic deafness [+]

OMIM:
DEAFNESS, AUTOSOMAL DOMINANT 2A; DFNA2A

External Links:
 
Xenbase Gene ID XB-GENE-5817035 XB-GENE-6489205 XB-GENE-17338012
Gene Symbol kcnq4 kcnq4.L kcnq4.S
Chromosome Chr2 Scaffold1583
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 6.0
CDS Gene model
Entrez Gene 780386
mRNA RefSeq
Protein NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine kcnq4 kcnq4.L kcnq4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards KCNQ4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Kcnq4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Kcnq4 Ensembl
zebrafish
LOC101887046 Ensembl
chicken
GEISHA KCNQ4 Ensembl
fruit fly
worm
Publications
First KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness., Cell 1999  
Most Recent In silico re-engineering of a neurotransmitter to activate KCNQ potassium channels in an isoform-specific manner., Commun Biol 2019                      
All View All Papers 2 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 10 terms 0 term 0 term
PANTHER kcnq4
KEGG Pathways K04929
KOG [P] Voltage-gated K+ channel KCNQ
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks kcnq4
ORFs kcnq4 ORF1
Clones Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info