st8sia1 Summary [species: Xenopus laevis and Xenopus tropicalis]

Summary

Expression

XB-GENEPAGE-5824738

[provisional- machine annotated only]

Gene Symbol: st8sia1 [Predicted: Source is Human Entrez Gene]

Gene Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 [Predicted: Source is Human Entrez Gene]

Synonyms: Xlgd3, siat8, siat8a, st8sial Add Xenopus synonyms

Gene Function: Sialyltransferase

Interactants: cer1(1) , chdh(1) , chrd(1) , gsc(1) , otp(1) , t(1) , ugcg(1) View All

XB-GENE-5824739

XB-GENE-5824746

Molecules	tropicalis	laevis
Gene	JGI XT Genome 4.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
	Entrez Gene	Entrez Gene
mRNA	Refseq >NM_001003659\|Xenopus (Silurana) tropicalis ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 (st8sia1), mRNA AGATGCTGCTGCAGAGACGGAGCCTCACACACTCCGGGGCAGAGAGAGGGGCAGGTAGGGGGCAGGGGGGTGGGATGAGTTGCCCCAGATGAAGCTGCAGGGGAGCAGGATGTGGCTTTGCCCCCGGACCCGCTTACCGGTCGGTGCCAGCGCCCTGGGCTTCCTGATCCTGTGTTGGCTCTATGTCTTCCCCGGGTACCGGCTCCCCGGGCACAAGGAGATGGTGCGGGAGGTTCTGCGGTTCGGCCCGGGCTGGAGGAAGAACCGGACTGAGATGGACTCATTCAGGAAGTTGCTGCAGGATTGCTGTGACCCCCCACATCTCTTCTCCTTGACCAAAGTCAACACCCCCCTGGGTGAGAATCTCTGGTTCGACGGGGAGTTTTTCCACTCACTCACCATAGACAACTCCACCCGCAGCCTCTTCCCCCAGGATACCCCCTTCAAGCTTCCATTGAAGAGATGCTCTGTGGTGGGAAATGGTGGGATTCTGAAGAACAGCCGCTGCGGGGAGCAAATAGATGAAGCGGACTTTGTTATGCGGTGCAACCTGCCACCCCTCTCCCGGGAGTACACAGAGGATGTCGGAACCAGAACCCAACTCGTCACAGTGAATCCCTCAATTATCGATAAAAGGTACCAGAACCTGTTGTGGTCCAGGAAGTCGTTTGTGGAGAACCTGAGGGTGTACCAGCAGAGCTACGTGTATATGCCAGCCTTCTCCACCAAGAGAGGAACCGACCCTTCCCTCCGGGTCTACTACACCCTGGCAGACTTCGGTACCAATCAGACGGTTCTGTTCGCCAACCCCAACTTTCTGCGCAACGTGGGCAAGTTCTGGAAGAGTAGAGGGATCCACTCCAAACGCCTCTCCACGGGGCTCTTCATGGTCAGCGCCGCCCTGTCCCTGTGCGAGGAAGTGACGATCTATGGGTTCTGGCCGTTCCAGATGGACCTGGGGGGCCGCTACATCAGCCATCACTATTACGATAACACGTTGCCTTTATCGGGGGTGCACGCTATGCCCGAGGAGTTCCTCCAGCTGTGGCTCCTACATAAAAGCGGGGTGCTACAGATGCAGCTGGACCAGTGCAAGAAGGACGTCTCTTCCCAAAAGCCCCACTGAAAGGGGAAACGGGGGGCAGAGGATTGGGATTTGGGGGGGTTTAAGAACATTGGGAAACTCATGGGCGTGGCCTGCGATGGACGAGACCACGGGGGCGTGTCCGTGCCAAACGCGTCTCTGATACCTTTCCTGCAGGGAGTTGTACAGTAACGAACATCTGTTTGTAATTATTTTGAATGTGAAAAAACTGAAT	Refseq >NM_001089619\|Xenopus laevis ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 (st8sia1), mRNA GCGGATGTGGGGCAGATGGAGAGGGGCGGGAGGTCGGAGAGGGGTCGCACAGCCGGTGATTCCGCAGATGAAGCTGTTGGGGGGGCGGGTGCCGCTCGGTGCCAGTGCCCTGGGGCTTCTCATTGTCTGTTGGTTTTACATCTTCCCCGGGGGGGAGCGACTCCCGGGACACAAAGAAATGATCCGGCAGGTTCTACAGTTCGGCCCGAGATGGGGGAGAAACCGGAGCAGCGGCGACTCCTTCAGGAAGCTGCTGCAGGATTGCTGCGACCCCCCACGTCTCTTCTCTATGACTAAAGCCAATACTGCGCTGGGGGAGAATCTCTGGTACGACGGGGAGTTTTTCCAGTCACTCACCATTGACAACACCACCCGCAGCCTCTTCCCCCAGGATACGCCCATCAAGCTTCCATTGAAGAGATGCTCTGTGGTGGGAAACGGTGGGATTCTGAAGAACAGCCGCTGCGGGGAGCAAATCGATGAAGCGGATTTTGTCATGCGATGCAACTTGCCCCCACTCTCCCGGGAATACACTGATGATGTGGGAACCAAAACCCAACTTGTCACAGTCAACCCCTCAATCATCGATAAAAGGTTCCAGAACTTGTTGTGGTCCAGGAAGTCATTTGTGGAGAGTGTGAGTGTGTACAAGCAGAGCTACGTGTATATGCCGGCTTTCTCCACCAAGAGAGGGACGGACCCTTCACTTCGGGTCTATTACACATTGGAAGATTTTGGTACCAATCAGACGGTTCTATTTGCCAATCCCAACTTCCTGCGCAATGTGGGCAAGTTCTGGAAGAGTAAAGGGGTTCACTCTAAACGACTCTCCACAGGGCTTTTCATGGTCAGCGCTGCCCTGTCTCTGTGCGAGGAGGTTACAATCTATGGGTTTTGGCCGTTTCAGATGGACCTAGGTGGGAGGCACATCAGCCATCACTATTATGATAACATGTTGCCTTTATCGGGGGTCCACGCTATGCCTGAGGAGTTCCTCCAGCTCTGGCATCTCCATAAAAGTGGGGTGTTACAGATGCAGCTGGATCAGTGCAAGAAGGATGTCTCTTCCAAAAAGCCTCACTAAAAGGGAATGTGGGGGAACAGGGCTTCCGGGGCAGAAATTGGGAACTTTTGGAGATTAAGAACATTGAGAAACTCAGCATTTTTAATCATGGGCGTGGCCTGTGATGTATGAGACCCCAGGGGCGCATAAGTGCCAAAAACACGATACTGGGACCTGCGGACTCTTTCCTTTCCTGCAGGGAGTCAGCAGGGGAGTTGTACAGTAACGAACACTTTTGTAATTATTTCTGATGAGAATGTTGGAAAACTGAATGTAGTAACTTCTTATTCTTTATATCACACTGAACGCACCAGGGTGGGCTTTAGTGTCATCAGGAATAGATTGGGGTCTCCGCCTCCCTGAAATACTGACCCCCCCACTTCCCTTATATTTCGTTTATTCATTTATATTTTATAACAATTTCATGGGCAGCTACAAAATCCAGAATTCAATTTCGCTTTGGTTTGGCGTCTGGTCGCTCAACCCCTCAGGGGGCGGCTCCTGCTTTGCCGGGGGGGAGGAGGAAAGGCCAAGTGAATACTGTGAAGAGCATTTTTACACGGTTATTCTGCATGAATGGGATCTTTTTATAAGAACCAATAATAATAATTCTGAGCCAATTACTTGAATGATGGGATGAGGGGGAGGAGCACCCTGCATGTTCCTCATTCATTTTGCACAGTCTTTTTGTACCTTCAGCACTTTCCTGTTTTTGCTCTTTGCAGAAAATAAGCCCCAGTAGTGATGGGAGTTAGTTTCACTATAAACCTAGCCCTAACCCTAATCCTAACCCTAATGCACTTACCATAACCCCTAACCCTTATACACCAACCCTAACCCTTATATACCAACCCTAACATTTAACCCTTATACACCAACCCTAACCCCTATCCCTTATACACCAACCCTAACCCCTATCCCTTATACACCAACCCTAACCCTGGGATCTGATGAGATTTCACTAACCTTTTGCCCCCTTTCCTCCTTCGCCTTTATTTTTATGGCTGCCTGTCTGCTTATGTCACCCCCATGTTCTCCATGTTTCTGCCTCCATGTGCACTGTGCCCTCCCCCTATTATTCCAAGCACGCCTCTTCTTAAAGAATAAAACCCAATAACAAGTGAAAAAAAAAAAAAAAA
Protein	Refseq >NP_001003659\|alpha-N-acetylneuraminide alpha-2,8-sialyltransferase [Xenopus (Silurana) tropicalis] MKLQGSRMWLCPRTRLPVGASALGFLILCWLYVFPGYRLPGHKEMVREVLRFGPGWRKNRTEMDSFRKLLQDCCDPPHLFSLTKVNTPLGENLWFDGEFFHSLTIDNSTRSLFPQDTPFKLPLKRCSVVGNGGILKNSRCGEQIDEADFVMRCNLPPLSREYTEDVGTRTQLVTVNPSIIDKRYQNLLWSRKSFVENLRVYQQSYVYMPAFSTKRGTDPSLRVYYTLADFGTNQTVLFANPNFLRNVGKFWKSRGIHSKRLSTGLFMVSAALSLCEEVTIYGFWPFQMDLGGRYISHHYYDNTLPLSGVHAMPEEFLQLWLLHKSGVLQMQLDQCKKDVSSQKPH UniProtKB	Refseq >NP_001083088\|alpha-N-acetylneuraminide alpha-2,8-sialyltransferase [Xenopus laevis] MWGRWRGAGGRRGVAQPVIPQMKLLGGRVPLGASALGLLIVCWFYIFPGGERLPGHKEMIRQVLQFGPRWGRNRSSGDSFRKLLQDCCDPPRLFSMTKANTALGENLWYDGEFFQSLTIDNTTRSLFPQDTPIKLPLKRCSVVGNGGILKNSRCGEQIDEADFVMRCNLPPLSREYTDDVGTKTQLVTVNPSIIDKRFQNLLWSRKSFVESVSVYKQSYVYMPAFSTKRGTDPSLRVYYTLEDFGTNQTVLFANPNFLRNVGKFWKSKGVHSKRLSTGLFMVSAALSLCEEVTIYGFWPFQMDLGGRHISHHYYDNMLPLSGVHAMPEEFLQLWHLHKSGVLQMQLDQCKKDVSSKKPH UniProtKB

Genomic	tropicalis
Genome Browser	Xenbase JGI Ensembl UCSC	Xenbase

Synteny	Metazome

Expression	tropicalis	laevis
UniGene	Str.24556	Xl.29879
Unigene EST Profile	EST Profile	EST Profile
GEO data		GEO
Images	1 expression image(s) for tropicalis and laevis

Orthology	MOD	Entrez Gene	Genetic Phenotypes	Morphants
human	OMIM:Gene, HGNC	ST8SIA1
mouse	MGI	St8sia1	All(5) Targeted, knock Out(1) Targeted, other(3)
zebrafish	ZFIN	st8sia1	1 Lines(s)

Publications
First:		Cloning and functional characterization of two key enzymes of glycosphingolipid biosynthesis in the amphibian Xenopus laevis. [Dev Dyn 2008]
Most recent:
		View All Papers

Functional Ontologies
GO: Molecular:		alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity sialyltransferase activity
Biological:		metabolic process protein amino acid glycosylation
Cellular Component:		membrane
EC:		a-N-acetylneuraminate a-2,8-sialyltransferase
KOG:		[G] Sialyltransferase

Reagents	tropicalis	laevis
Clones	open biosystems	open biosystems
	geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0	Str.24556.1.S1_at	Xl.16346.1.A1_at
Affymetrix 2.0		Xl2.29879.1.S1_a_at [+] Xl2.29879.2.S1_a_at Xl2.29879.1.S2_at

Symbol legend[+]