[provisional- machine annotated only] Gene Symbol: gad1.2 [Predicted: Source is Human Entrez Gene] Gene Name: glutamate decarboxylase 1 (brain, 67kDa), gene 2 [Predicted: Source is Human Entrez Gene] Synonyms: gad, scp, cpsq1 Add Xenopus synonyms Gene Function: Glutamate decarboxylase and related proteins Interactants: th(3) , mtnr1c(2) , rpe(2) , smad1(2) , smad2(2) , tgfb1(2) , zic1(2) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001126954|Xenopus (Silurana) tropicalis uncharacterized LOC100145511 (LOC100145511), mRNA GATTTCTCTACAGGTTCCAGTGGCATACGCAAAATGGAAAAAGTTGGTACATGTGCAGATGAAGGAAATAGTCAGCCCAAGCTACTCCATGAAAAACACATTTGTCAAGAGAAGGCCAATGAAGAGAGGATAATGCACAGTGAAAAATATATTTCTGATTTCTCAAACATTTATTCCACAGACCTACTCCCTACAAGAAATGGAGAAAAGTGCACAGAACAATTTTTAATTGAAGTTTTACGTATTCTTTTGAATCACATAAAAAAAACCTACGATGGGGAAAGTAAAGTTCTTGACTTCCATCATCCACACCAGCTACTAGAAGGATTAGAAGGATTTAATTTGGAATTATCTGACCAGCCAGAGCCTTTAGAGCAAATTCTTGTGGATTGTAGTGATACTCTTAAATACAGCATTAAAACAGGACATCCACGTTACTTTAATCAGCTCTCCTGTGGCCTTGATATAATTGGACTAGCTGGTGAATGGCTGACTGCAACTGCTAATACAAACATGTTTACATATGAAATTGCACCAGTGTTTATAATCATGGAAGAAATTGTGCTGAAAAAAATGCAAGAGATTATTGGATGGGGAGAAAATGAAGCAGATGGTATATTCTCTCCTGGTGGAACAATTTCCAACCTTTATAGCCTTCAAGCAGCTCGTTACAAATATTTTCCCATGGTGAAAACAAAAGGAATGGCAGCACTTCCACAGATTGTTATTTTTACATCTGAACAGAGTCACTACTCATTTAAAAAAGCATCTGCAATTCTTGGTATTGGAACTGACAATGTCATTGCAATAAAGTGTGATGAAAGGGGTAAAATGATTCCATCTGACTTGGAAGATAAAATTCTGAAAGCAAAAAGACAAGGACAACATCCATTTTATGTTAGTGCTACAGCTGGGACAACAGTATATGGTGCATTTGATCCCCTCATCACTATTGCTGACATTTGTAAGAGATATGGACTCTGGATGCATGTTGATGCAGCCTGGGGTGGTGGATTACTGTTGTCCAAAAAACATCGCTATAAAATGAATGGAATTGAGAGAGCTAATTCTGTCACTTGGAATCCCCACAAAATTATGGGAGTCCCACTACAATGCTCAGCAATCCTTATTCGACAAAAGGGTCTTCTGCAGGCATGTAACCAGCAATGTGCAGATTATCTCTTCCAAATGGACAAACCTTACGATACAGCTTATGATACAGGAGACAAGACAATCCAGTGTGGCCGACATGTGGATATCTTTAAACTCTGGTTAATGTGGAAGGCAAAGGGAAGCTGTGGCTTTGAACTTCAAATAAACAGATGCCTTGAACTTTCAGAATATTTGTACAATAAGCTACAATCAAAATCAAATTTTGAACTTGTCTTCCGTGATAAGCCGGAGTACACAAATGTCTGCTTCTGGTATATTCCACCTAGTCTGGAACATGTCCCAAGAGATAAGGAATGGAAAGCAAGGCTGCATAAGATTGCTCCGCAGATTAAAGCCCGTATGATGGAAGAAGGAACAGTTATGGTCAGTTACCAGCCTCAAGGAGACAAACCTAACTTTTTCAGGATGGTTTTCTCAAATCCAGCTTCTAAAAAATCTGATGTTGATTTTCTTCTCGAAGAAATTGAAAGATTAGGAAAAGGCTTGTGACATTCAGCACATTTACATTAATTTTATTTATTACATTTTAATGTAATAAATCTCCAAATTTAATAATTTAATCAGATTATTTCTTTATGAATCCTAACTGTATAGACTTATGGTTTTACAATAGAAAAAACTTGTTTTGTGTGTTACTTTTAACATTGACTTGTGAAATATACTGTTCCTGTTCCTATACATATTTATTTCCACAAAACCAAACAATAGATTGATTTTTAATGTTATGTTAAAATACTGTTGTTTTAGTTGTAAAGGATGGTATGTGCATTCATAGCTAAGTTTCTGAAGACTTCTTCAATATGAAACATCCTATGGCAGCAGCTGTACAGGCAAATAATGTTCCATAATCTGGGATTAGCAAAATAATTTCGCCACGTGGCCTTTGACGCGGGCATTGCTTTCTCTGACGTGTGCGTTGACTTTGGACATGCACATCTAAAGAATGACACACGCGTAAAAAATAAACAGACGCGTCAGAGAAAGTGACATCTGTGTCAGCCGCACAAATTATTTTGCCCATCTCTATAGTGCATGAATGTGCATGATACCTATTTTATGTTAACTAGTATCCCCATCTGTACATTATTTGAACTTTAAAACCACAGCGATTCTTAAACTTTTATAGAGATTTGCATGCAAGTGATTTAAATTATTTTTTTTTAATTTTATATGTAAAATGCATTGGGTTTGTTTTTTCCTGTGTGTTTACTTAAACATTTTAACATTTTTTTTTGTAGTTGAAATCTAAATAAACTCTGTTTTGGGTTGCAAAAAAAAAAAAAAAAAA	NCBI Nucleotide >BC157450|Xenopus laevis hypothetical protein LOC100137647, mRNA (cDNA clone IMAGE:8328787), partial cds CCCACGCGTCCGGGAATCTCCTGTTAGTGGGACATCAGTGGTGGATTTCTCTACAGTTTCCAGTGTCATACACAAAATGGAAAATGTTAGTACACACATGGATGAAGGAAAAAGTCCGTCCAAGATGCTACATGAAAAACACATTTGTCAAGAGTCTACCAGTGAAGATAGGCTAAAGAGCAATGAAAAATATATTTCTAATTTCTCAAACTTTTATTCCTCAGACCTGCTCCCTGCAAGAAATGGAGAAAAGTGCACAGAACAATTTTTAGCTGAAATCTTGCAAATTCTCTTCAATCATATTAAGAAGACCTATGACGGCAAAAGCAAAGTTCTTGACTTTCATCATCCACACCAGCTACTAGAAGGACTGGAAGGCTTTAATTTGGAATTATCTGACCAGCCAGAGCCTTTAGAACAAATTCTTGTTGATTGTAGTGGTACTCTAAAATATAGCATAAAAACAGGACATCCACGTTACTTCAATCAACTTTCCAGTGGCCTTGATATAATTGGACTAGCTGGTGAATGGCTGACTGCAACTGCTAACACAAACATGTTTACATATGAAATTGCACCAGTGTTTATAGCCATGGAGGAGATTGTGCTGAAAAAAATGCAAGAGATAATTGGATGGGGAGAAAATGAAGCAGATGGCATATTCTCTCCCGGTGGAACAATCTCCAATCTTTACAGCCTTCAAGCAGCTCGTTACAAATATTTCCCTTTAGTAAAAACAAAGGGAATGGCAGCACTTCCACAGATTGCGGTCTTTACATCAGAACAGAGTCACTACTCTTTTCGAAAAGCAGCCTCAGTTCTTGGTATTGGAACAGACAATGTCATTGCAGTAAAGTGTGATGAAAGGGGTAAAATGATTCCATCTGATTTGGAAGATAAAATTCAGAAAGCTGAAAGACAAGGACAACATCCATTTTATGTCAGTGCCACAGCTGGGACAACGGTGTTTGGTGCATTTGATCCCCTCGTCAGTATTGCTGATATTTGTAAAAGATATGGACTCTGGATGCATGTTGATGCAGCTTGGGGTGGTGGATTACTGTTGTCTAAAAAGCATCGCCATAAACTGAATGGAATTGAAAGAGCTAATTCTGTCACTTGGAATCCTCACAAAATTATGGGAGTCCCACTGCAATGCTCTGCAATACTTATTTGGCAAAAGGGTCTTCTGCAGTCATGTAACGAGCAATGTGCAGATTATCTTTTTCAAATGGACAAGCATTATGATACATCCTATGACACTGGAGACAAGACAATCCAGTGTGGCCGCCATGTGGATGTGTTTAAATTCTGGCTAATGTGGAAGGCAAAGGGTACCTGTGGCTTTGAGCTCCAAATAAACAAAATCCTTGAACTTGCAGAATACTTGTATAACAAGCTCAAATCGAAACCAAACTTTGAACTTGTCTTTCATGATAAGCCCGAGTGCACAAATGTCTGCTTCTGGTATATTCCACCTAGTCTGGAACATGCACCAAGAGATGAGGAATGGAACGCAAAACTGCATAAGGTTGCTCCACAGATTAAAGCCCGTATGATGGAAGAAGGTACAGTTATGGTCGGTTACCAGCCTCAAGGAGACAAACCTAACTTTTTCAGGATGGTTATTTCAAATCCAGCTTCTAAAAAATCTGATATTGATTTCCTTCTTGAAGAAATGGAAAGATTAGGAAAAGACTTGTAGCACGTGTATTTTACAAATTTTTATTTAAATTTATTTTAAGATGCTTTTATTAGTTGGAAGAACCGACTCTTAATTTTAGTCCTTGGTTGAATCTCAACAGCTCTACATTTTTAAAATGGGGAAAATTTCCTTGTATATTGGATTACCTTTTTAACAGCTGACAATGTTGTTATTGCTTCTTGTTACAACACACAACTTTGGCATCTTCCACAAAACTTAACAATAGATTGAATCTTCTTTTACAACTCAATTTGTTTTTAAAATAGGTTACAACTCTGTGGTTTTAGCTACAGTATATAGGTTAATTGTCTGTTATGTCATCTTGGCCATATAACCGAAGACTTCAATATGAAACAAATTGAGGTATATGGGAACAGCTGTACAGGCAAATGTCCAATAAATAGTGAGTGTATGTGTGCATACTGGACTGGTAATCATCTATTTGAATCTAAAACCACAATCCTGCTAAAATTTGTATACATTTAGATTTTTAGTTTTCCTTGAAAAGCTTAATAAATGATTTTATCTGTAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001120426|uncharacterized protein LOC100145511 [Xenopus (Silurana) tropicalis] MEKVGTCADEGNSQPKLLHEKHICQEKANEERIMHSEKYISDFSNIYSTDLLPTRNGEKCTEQFLIEVLRILLNHIKKTYDGESKVLDFHHPHQLLEGLEGFNLELSDQPEPLEQILVDCSDTLKYSIKTGHPRYFNQLSCGLDIIGLAGEWLTATANTNMFTYEIAPVFIIMEEIVLKKMQEIIGWGENEADGIFSPGGTISNLYSLQAARYKYFPMVKTKGMAALPQIVIFTSEQSHYSFKKASAILGIGTDNVIAIKCDERGKMIPSDLEDKILKAKRQGQHPFYVSATAGTTVYGAFDPLITIADICKRYGLWMHVDAAWGGGLLLSKKHRYKMNGIERANSVTWNPHKIMGVPLQCSAILIRQKGLLQACNQQCADYLFQMDKPYDTAYDTGDKTIQCGRHVDIFKLWLMWKAKGSCGFELQINRCLELSEYLYNKLQSKSNFELVFRDKPEYTNVCFWYIPPSLEHVPRDKEWKARLHKIAPQIKARMMEEGTVMVSYQPQGDKPNFFRMVFSNPASKKSDVDFLLEEIERLGKGL	NCBI Protein >AAI57451|LOC100137647 protein [Xenopus laevis] PRVRESPVSGTSVVDFSTVSSVIHKMENVSTHMDEGKSPSKMLHEKHICQESTSEDRLKSNEKYISNFSNFYSSDLLPARNGEKCTEQFLAEILQILFNHIKKTYDGKSKVLDFHHPHQLLEGLEGFNLELSDQPEPLEQILVDCSGTLKYSIKTGHPRYFNQLSSGLDIIGLAGEWLTATANTNMFTYEIAPVFIAMEEIVLKKMQEIIGWGENEADGIFSPGGTISNLYSLQAARYKYFPLVKTKGMAALPQIAVFTSEQSHYSFRKAASVLGIGTDNVIAVKCDERGKMIPSDLEDKIQKAERQGQHPFYVSATAGTTVFGAFDPLVSIADICKRYGLWMHVDAAWGGGLLLSKKHRHKLNGIERANSVTWNPHKIMGVPLQCSAILIWQKGLLQSCNEQCADYLFQMDKHYDTSYDTGDKTIQCGRHVDVFKFWLMWKAKGTCGFELQINKILELAEYLYNKLKSKPNFELVFHDKPECTNVCFWYIPPSLEHAPRDEEWNAKLHKVAPQIKARMMEEGTVMVGYQPQGDKPNFFRMVISNPASKKSDIDFLLEEMERLGKDL

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.6300 [+] Str.45967	Xl.24790
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		1 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	GAD1	OMIM:603513
mouse		MGI	Gad1	All(15) Targeted, knock Out(3) Targeted, other(11)
zebrafish		ZFIN	gad1b	2 Lines(s)

Publications
First:		Inhibitory neurones of a motor pattern generator in Xenopus revealed by antibodies to glycine. [Nature 1986]
Most recent:		The spatio-temporal expression of ProSAP/shank family members and their interaction partner LAPSER1 during Xenopus laevis development. [Dev Dyn 2011]
		View All Papers

Functional Ontologies
GO: Molecular:		carboxy-lyase activity
Biological:		amino acid metabolic process
Cellular Component:
EC:
KOG:		[E] Glutamate decarboxylase and related proteins

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.45967.1.A1_at [+] Str.6300.1.S1_at	Xl.24790.1.A1_at
Affymetrix 2.0			Xl2.24790.1.S1_at

Symbol legend[+]

- Blast this sequence
   - Literature Or Expression Images