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Summary Expression Gene Literature (24) Nucleotides (345) Proteins (26) Interactants (110) Wiki
XB-GENEPAGE-5830281

[provisional- machine annotated only]
Gene Symbol: gad1.2 [Predicted: Source is Human Entrez Gene]

Gene Name: glutamate decarboxylase 1 (brain, 67kDa), gene 2 [Predicted: Source is Human Entrez Gene]

Synonyms: gad, scp, cpsq1 Add Xenopus synonyms

Gene Function: Glutamate decarboxylase and related proteins

Interactants: th(5) , slc17a7(4) , actl6a(3) , smad1(3) , smad2(3) , trhd(3) , act3(2) View All

Disease Associations: CEREBRAL PALSY, SPASTIC QUADRIPLEGIC, 1; CPSQ1
 
Xenbase Gene ID XB-GENE-5830282 XB-GENE-5830385
Current JGI Annotation gad1.2 gad1.2.L
Molecules tropicalis laevis
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq NCBI Nucleotide
Protein Refseq NCBI Protein
Genomic tropicalis laevis
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v7.2 gene model
Links
tropicalis 4.1 synteny Metazome
Expression tropicalis laevis
UniGene Str.6300 [+] Xl.24790
Unigene EST Profile EST Profile EST Profile
GEO data GEO
Images 1 expression image(s) for tropicalis and laevis
Phenotype tropicalis laevis
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Morphants
human
OMIM:Gene, HGNC GAD1 OMIM:603513
mouse
MGI Gad1 All available mutants
zebrafish
ZFIN gad1b All
chicken
Publications
First: Inhibitory neurones of a motor pattern generator in Xenopus revealed by antibodies to glycine. [Nature 1986]
Most recent: Methylmercury exposure during early Xenopus laevis development affects cell proliferation and death but not neural progenitor specification. [Neurotoxicol Teratol 2015]
View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies
GO: Molecular: carboxy-lyase activity
      Biological: amino acid metabolic process
      Cellular Component:
EC:
KOG: [E] Glutamate decarboxylase and related proteins
Reagents tropicalis laevis
CRISPR / TALEN CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
Affymetrix 1.0 Str.45967.1.A1_at [+] Xl.24790.1.A1_at
Affymetrix 2.0 Xl2.24790.1.S1_at

Symbol legend[+]

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