Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (17) GO Terms (19) Nucleotides (49) Proteins (22) Interactants (73) Wiki
XB-GENEPAGE-5838892
Gene Symbol:
gria4

Gene Name:
glutamate receptor, ionotropic, AMPA 4

Synonyms:
glur4 ( Add synonyms , Nomenclature history )

Gene Function:
glutamate-gated ion channel receptor subunit

Protein Function :
Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neur...[+]


InterPro :
NAD(P)-bd dom sf , SDR fam , Sc DH/Rdtase CS , Znf C2H2 sf [+]

Interactants:
Loading ...

Diseases: 


OMIM:
NEURODEVELOPMENTAL DISORDER WITH OR WITHOUT SEIZURES AND GAIT ABNORMALITIES; NED

External Links:
 
Xenbase Gene ID XB-GENE-5838893 XB-GENE-6372208 XB-GENE-17334550
Gene Symbol gria4 gria4.L gria4.S
Chromosome Chr2 Scaffold45
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2
CDS Gene model Gene model
Entrez Gene 100125052
100294517
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine gria4 gria4.L gria4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards GRIA4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Gria4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Gria4 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR gria4b gria4a ZFIN Ensembl
chicken
GEISHA GRIA4 Ensembl
fruit fly
worm
Publications
First Cloning of a novel glutamate receptor subunit, GluR5: expression in the nervous system during development., Neuron 1990  
Most Recent Heterogeneity of the astrocytic AMPA-receptor transcriptome., Glia 2018  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 5 terms 0 term
PANTHER gria4
KEGG Pathways K05200 K05200
KOG [PET] Glutamate-gated AMPA-type ion channel receptor subunit GluR2 and related subunits
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks gria4
ORFs gria4 ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info