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Summary Expression Gene Literature (81) GO Terms (8) Nucleotides (88) Proteins (31) Interactants (124) Wiki
XB-GENEPAGE-5842249
Gene Symbol:
slc22a6

Gene Name:
solute carrier family 22 (organic anion transporter), member 6

Synonyms:
oat1 , paht , roat1 , nkt ( Add synonyms , Nomenclature history )

Gene Function:
Synaptic vesicle transporter SVOP and related transporters (major facilitator superfamily)

Protein Function :
Involved in the renal elimination of endogenous and exogenous organic anions. Mediates the sodium-independent uptake of p-aminohippurate (PAH), cidofovir, adefovir, 9-(2-phosphonylmethoxyethyl) guanine...[+]


InterPro :
TMP21-related , GOLD dom

Interactants:
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Diseases: 


External Links:
1/2
 
Xenbase Gene ID XB-GENE-5842250 XB-GENE-17333734 XB-GENE-5842265
Gene Symbol slc22a6 slc22a6.L slc22a6.S
Chromosome Chr4 chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 100487511
447487
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine slc22a6 slc22a6.L slc22a6.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SLC22A6 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Slc22a6 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Slc22a6 Ensembl
zebrafish
ZFIN, AGR slc22a6l ZFIN Ensembl
chicken
fruit fly
worm
Publications
First Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney., J Biol Chem 1997  
Most Recent Dual actions on gout flare and acute kidney injury along with enhanced renal transporter activities by Yokuininto, a Kampo medicine., BMC Complement Altern Med 2019          
All View All Papers 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 8 terms 0 term 3 terms
PANTHER slc22a6
KEGG Pathways K08203 K08203
KOG [R] Synaptic vesicle transporter SVOP and related transporters (major facilitator superfamily)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks slc22a6
ORFs slc22a6.S ORF1
Clones Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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