Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (42) Nucleotides (109) Proteins (20) Interactants (153) Wiki

[provisional- machine annotated only]
Gene Symbol: mcm3 [Predicted: Source is Human Entrez Gene]

Gene Name: minichromosome maintenance complex component 3 [Predicted: Source is Human Entrez Gene]

Synonyms: Xmcm3, mmcm3 Add Xenopus synonyms

Gene Function: DNA replication licensing factor, MCM3 component

Interactants: mcm2(21) , mcm7(11) , mcm5(9) , cdc6(7) , mcm4(7) , mcm6(7) , cdc45(6) View All

Disease Associations:
  XB-GENE-5857845 XB-GENE-5857895
Molecules tropicalis laevis
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 Ensembl 4.1 GBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein Refseq UniProtKB
Genomic tropicalis laevis
Genome Browser
tropicalis genome v8.0 gene model

laevis genome v7.2 gene model

tropicalis 4.1 synteny
Expression tropicalis laevis
UniGene Str.4149 Xl.4509 [+]
Unigene EST Profile EST Profile EST Profile
GEO data GEO
Images 0 expression image(s) for tropicalis and laevis
MOD Entrez Gene Genetic Phenotypes Morphants
MGI Mcm3 All
zebrafish (a-gene b-gene)
ZFIN mcm3 All
First: Fission yeast cdc21+ belongs to a family of proteins involved in an early step of chromosome replication. [Nucleic Acids Res 1992]
Most recent: Protein Phosphatase 2A and Cdc7 Kinase Regulate the DNA Unwinding Element Binding Protein DUE-B in Replication Initiation. [J Biol Chem 2014]
View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies
GO: Molecular: ATP binding
ATP-dependent DNA helicase activity
ATP-dependent RNA helicase activity
      Biological: DNA replication initiation
      Cellular Component: nucleus
EC: adenosinetriphosphatase
KOG: [L] DNA replication licensing factor, MCM3 component
Reagents tropicalis laevis
CRISPR / TALEN Design E-CRISP / Other tools
Design E-CRISP / Other tools
GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
Antibody Mcm3 Ab1 Mcm3 Ab1
Affymetrix 1.0 Str.4149.1.S1_at Xl.4509.1.S1_at
Affymetrix 2.0 Xl2.4509.2.S1_a_at

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [3.2.3]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556