mcm3 Summary [species: Xenopus laevis and Xenopus tropicalis]

Summary

Expression

XB-GENEPAGE-5857844

[provisional- machine annotated only]

Gene Symbol: mcm3 [Predicted: Source is Human Entrez Gene]

Gene Name: minichromosome maintenance complex component 3 [Predicted: Source is Human Entrez Gene]

Synonyms: Xmcm3, mmcm3 Add Xenopus synonyms

Gene Function: DNA replication licensing factor, MCM3 component

Interactants: mcm2(14) , mcm5(6) , mcm7(5) , cdc6(4) , mcm6(4) , mcm6.2(4) , cdc7(3) View All

XB-GENE-5857845

XB-GENE-5857895

Molecules	tropicalis	laevis
Gene	JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
	Entrez Gene	Entrez Gene
mRNA	NCBI Nucleotide >BC166313\|Xenopus tropicalis hypothetical protein LOC100158601, mRNA (cDNA clone IMAGE:7538928), partial cds CACGGGGCTGGGTTTGAGGATCATGAGCTGCGGGAGGCACAGAGGGAATATCTAGATTTCCTGGATGATGATCAAGATCAAGGCCTTTACCATGGCAAGGTTAGAGACATGATTGGCTCCAACGAGCACCGGCTGATCATCAACCTGAATGATGTGAGACGGAAGAATGAGAAGAGAGCAAACCTGTTGCTGAATAACGCGTTTGGAGAAACTATCGCTTTTCAGCGGGCATTAAAAGATCTGGTGGCTTCCATTGATGCAACGTATGCCAAGCAGTTTGAGGAGTTCAGCGTTGGATTTGAAGGCAGTTTTGGCAGCAAGCATGTCTCTCCCCGCACCCTAACAGCCAGTCTCCTGGGCTCTTTGGTTTGTGTGGAAGGGATAGTGACCAAATGTTCCTTGGTAAGACCCAAAGTGTTGCGTAGTGTCCATTATTGTCCGGCAACAAAAAAAACCCTTGAAAGGAAATACACAGACCTGACATCCCTGGAAGCATTCCCTTCCAGCTCCATTTATCCTACAAAGGATGAGGAAAACAACCCCCTGGAAACAGAATATGGGCTGAGCACTTACAGAGACCATCAGACTTTGAGCATTCAAGAAATGCCAGAAAAGGCCCCGGCTGGGCAGCTTCCCCGCTCTGTTGACATTATTGCAGATGACGATCTAGTGGATAAATGTAAACCGGGTGACAGAGTGCAGATAGTAGGAATATACCGTTGCCTACCATCCAAACAAGGGGGCTTCACATCTGGAACTTTCAGGACCATTTTATTGGCTAATAACATTAAACTGATGAGTAAGGAGATTGCTCCAACATTTTCAGCTGATGATGTAGCTAAAATCAAGAAATTCTGCAAAGCTCACTCCAAAGACATATTTGAACATTTAAGCAAATCCCTGGCACCCAGTATTCATGGCCACGAGTACATTAAGAAGGCCATTTTGTGTATGCTTCTTGGGGGAAATGAGAAGGTTCTTGACAATGGCACACGTATAAGAGGAGATATTAATGTTCTCTTAATAGGAGATCCCTCTGTTGCCAAGTCTCAGCTATTGCGGTATGTACTGTACACAGCTCCGCGAGCCATCCCTACCACTGGTAGAGGGTCCTCTGGAGTAGGGTTAACAGCAGCTGTCACAACTGATCAGGAAACTGGGGAAAGGCGCTTGGAAGCTGGGGCCATGGTGCTTGCAGACAGAGGTGTGGTGTGCATTGATGAATTTGACAAAATGTCTGATATGGACAGGACTGCAATCCATGAGGTGATGGAGCAGGGTCGTGTAACAATTGCGAAAGCAGGGATCCAAGCACGATTAAACGCCCGATGTAGTGTACTGGCAGCAGCAAATCCTGTTTATGGAAGGTATGATCAATATAGAACTCCCATGGAGAACATTGGTTTGCAAGATTCTCTGCTTTCAAGATTTGACTTGCTTTTTATTGTCCTGGACAAAATGGATGCAGACAACGATCGAGAAATTGCTGACCATGTTCTGAGGATGCATAGATATAGAACTCCAGGGGAACAAGATGGTTATGCATTGCCTCTTGGATGCAGTGTTGAGATCTTTGCTACAGATGATCCAAATGCCTCAGATGTTACAGATCAAGAGCTGCAGATTTATGAGAAACATGACAATTTACTTCATGGGCCACGTAAAAACAAGTCAAAGATTGTGAGCATGCAGTTTATTCGGAAGTATATCCATGTTGCTAAACTGATTAAGCCTGTCCTGACTCCCGAGGCTGCTGACTACATATCTCAGGAATATTCCAAGATCCGGAACCACGATCAGATAAATAATGATAGTGCCAGGACTATGCCAGTTACTGCCAGAGCACTGGAAACCATGATCAGATTGGCCACTGCTCACGCTAAGGTCAGAATGAGCAAAACCATTGAGCGACAGGATGCTGAAACTGCCCTTGAGCTGGTACAGTTTGCTTATTTCAAGAAGGTCTTAGCAAAGGATAAAAAGAAAACTGACAAGGATCTGCATGATGAAATCTTAAGTCAAGACTCGGCAAGCCAAGAGAGCATTCGGAAAAGTTCTAGGCGTGCAGGAAAAATTGCTGACTCTCAAGATGATTCGATGGACCCGTACTCTTTTAGTGAGCAAGATAGCAGTCTAAATGAAACCCTTTCTCAGAGTTTGCGACCTCAACGGAAAAAAGCAGAAAGTCAAGATATCAAGCGCTCCTTGAGTCAAAACAGAACCAAAGAATTTAAAGCTGCACTTCTGAAAACCTTCAAGACCACCCGGTCACAGTCAGTTGCAGTCAGTCAGCTGTTTGAGCTCATCAACAAGGGGAATTCAGAGCCTTTTGAACTGAGTGAAGTGAAGGAAGCGCTGGACAATATGCAGAATGACAACCAAGTCATGGTGTCAGATGATGTTGTTTTCCTAATCTAATTTATATACTAAATTTATATTTATGAAAATAGATAACCAAAAATATTTTAAGTCCTATTAAATGTTTTTGTATACAAATCCTAAATAAACTCAGAGCAAACAGTCAAAAAAAAAAAAAAA	Refseq >NM_001087943\|Xenopus laevis minichromosome maintenance complex component 3 (mcm3), mRNA GCAATGGATTACGGAGGTGGGTTTGAGGATCATGAGCTGCGGGAGGCGCAGAGGGAATATTTAGATTTCCTAGATGATGATCAAGATCAAGGCCTTTACCATGGGAAGGTGAGGGACATGATTGGCTCCAATGAGCACCGGCTGATCGTCAACCTGAATGATGTGAGGAGGAAGAATGACAAAAGAGCCAACCTGATGCTGAATGATGCGTTTGCAGAAACTATTGCTTTTCAGAGGGCATTAAAAGATCTGGTGGCTTCCATTGATGCAACATATGCCAAGCAGTTTGAGGAGTTCAGTGTTGGATTCGAAGGCAGCTTTGGCAGCAAGCATGTCTCTCCCCGTACCCTAACAGCCAGTCTCCTGGGCTCTTTGGTTTGTGTGGAAGGGATCGTGACCAAATGTTCCTTGGTTAGACCCAAAGTAATGCGCAGTGTCCATTATTGTCCAGCCACCAAAAAAACCCTTGAAAGGAAATACTCTGACCTTACATCCCTGGAAGCATTTCCTTCTAGCTCCATTTATCCTACAAAGGATGAGGAAAACAACCCACTGGAAACAGAATATGGACTGAGCACTTACAAGGACCACCAAACCTTGAGTATCCAAGAAATGCCAGAAAAGGCCCCAGCTGGGCAGCTTCCTCGTTCTGTTGACATTATTGCAGATGATGATCTAGTAGATAAATGTAAACCAGGTGATAGAGTGCAGATAGTAGGGATATACCGTTGCCTTCCTTCCAAGCAAGGGGGCTTCACATCTGGAACTTTCAGGACCATATTATTGGCTAATAACATTAAGTTGATGAGTAAGGAGATTGCGCCAACATTTTCAGCTGATGATGTAGCTAAAATCAAGAAATTCTGCAAAGCTCATTCCAAAGACATATTTGAACATTTAAGCAAATCGTTGGCCCCCAGTATTCATGGCCATGAGTATATTAAGAAGGCCATTTTGTGTATGCTTCTTGGGGGCAATGAGAAGGTTCTTGAGAATGGCACACGTATAAGAGGAGATATCAATGTTCTCCTAATAGGAGATCCCTCAGTTGCCAAGTCTCAGCTATTGCGCTATGTACTGCACACAGCTCCACGAGCCATCCCTACTACTGGTAGAGGATCCTCTGGAGTAGGGTTAACGGCAGCTGTCACAACGGACCAGGAAACTGGGGAGAGGCGCTTGGAAGCTGGGGCTATGGTGCTTGCAGACAGAGGAGTGGTGTGCATTGATGAATTTGACAAAATGTCTGATATGGACAGGACTGCAATCCATGAAGTGATGGAGCAGGGCCGAGTGACAATTGCAAAAGCAGGGATCCAGGCACGATTAAATGCCCGATGTAGCGTACTGGCAGCAGCAAATCCTGTTTATGGAAGGTATGACCAATATAGAACTCCAATGGAGAACATTGGGTTGCAGGATTCTCTGCTTTCAAGATTTGACTTGCTTTTTATTGTCCTGGACAAAATGGATGCAGACAATGATCAAGAAATTGCTGACCATGTTCTGAGGATGCACAGATATAGGACTCCAGGGGAACAAGATGGTTATGCATTGCCTCTTGGATGCAGTGTTGAGATCTTTGCCACAGATGATCCAAATGCCTCTGATGTTACAGATCAAGAGCTGCAAATTTATGAGAAACATGATAATTTACTCCATGGGCCACGGAAAAACAAGTCAAAGATTGTGAGCATGCAGTTTATTCGGAAGTATATCCATGTTGCTAAACTGATAAAGCCCGTCCTGACTTCCGAAGCTGCTGACTACATATCTCAGGAATATGCAAAGATCAGGAACCACGATCAGATAAATAATGATAGTGCCAGGACAATGCCAGTTACTGCCAGAGCGCTGGAAACCATGATCAGATTGTCTACTGCTCACGCTAAGGTCAGAATGAGCAAAACCATTGAGCGCCAGGATGCTGAAACTGCACTTGAGCTGGTCCAGTTTGCCTATTTCAAGAAGGTCTTGGCAAAAGAAAAGAAAAAAACAGACAAGGATCTGCATGATGAAAACTTAAGTCAAGACACACTTAGCCAAGAGAGTGTTCGGAAAAGTTCTAGACGTGCAGGAAAAATTGCTGACTCTCAAGATGATTCAATGGACCCATACTCTTTTAGTGAGCAAGATAGCAGTCTAAATGAAAACCTTTCTCAGAGTTTAAGACCTCAACGGAAAAAAGCAGAAAGTCAAGATGGCAAGCGGTCCTTGAGTCAAAACAGGACCAAAGAGTTTAAAGCTGCCCTCCTGAAAGCCTTTAAGAGCAGTCGGTCACAGTCTGTTGCGGTCAGTCAGCTGCTGGAGCTCATCAACAAGGGGAATCCAGAGCCTTTTGAACGGAGTGAAGTAAAGGAGGCCTTGGACAATATGCAGAATGACAATCAGGTCATGGTGTCAGAAGATGTGGTTTTCCTAATCTAATTTATATTCTAAATTATATTTAAAAAATGGATTTCTAAAAATTAATCTATTTTTAAGTCCTAATATATGATTTTGTATACATGAGCTAAATAAACACAGAGCAGTTAAAAAAAAAAAAAAA
Protein	NCBI Protein >AAI66313\|LOC100158601 protein [Xenopus (Silurana) tropicalis] HGAGFEDHELREAQREYLDFLDDDQDQGLYHGKVRDMIGSNEHRLIINLNDVRRKNEKRANLLLNNAFGETIAFQRALKDLVASIDATYAKQFEEFSVGFEGSFGSKHVSPRTLTASLLGSLVCVEGIVTKCSLVRPKVLRSVHYCPATKKTLERKYTDLTSLEAFPSSSIYPTKDEENNPLETEYGLSTYRDHQTLSIQEMPEKAPAGQLPRSVDIIADDDLVDKCKPGDRVQIVGIYRCLPSKQGGFTSGTFRTILLANNIKLMSKEIAPTFSADDVAKIKKFCKAHSKDIFEHLSKSLAPSIHGHEYIKKAILCMLLGGNEKVLDNGTRIRGDINVLLIGDPSVAKSQLLRYVLYTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIQARLNARCSVLAAANPVYGRYDQYRTPMENIGLQDSLLSRFDLLFIVLDKMDADNDREIADHVLRMHRYRTPGEQDGYALPLGCSVEIFATDDPNASDVTDQELQIYEKHDNLLHGPRKNKSKIVSMQFIRKYIHVAKLIKPVLTPEAADYISQEYSKIRNHDQINNDSARTMPVTARALETMIRLATAHAKVRMSKTIERQDAETALELVQFAYFKKVLAKDKKKTDKDLHDEILSQDSASQESIRKSSRRAGKIADSQDDSMDPYSFSEQDSSLNETLSQSLRPQRKKAESQDIKRSLSQNRTKEFKAALLKTFKTTRSQSVAVSQLFELINKGNSEPFELSEVKEALDNMQNDNQVMVSDDVVFLI	Refseq >NP_001081412\|maternal DNA replication licensing factor mcm3 [Xenopus laevis] MDYGGGFEDHELREAQREYLDFLDDDQDQGLYHGKVRDMIGSNEHRLIVNLNDVRRKNDKRANLMLNDAFAETIAFQRALKDLVASIDATYAKQFEEFSVGFEGSFGSKHVSPRTLTASLLGSLVCVEGIVTKCSLVRPKVMRSVHYCPATKKTLERKYSDLTSLEAFPSSSIYPTKDEENNPLETEYGLSTYKDHQTLSIQEMPEKAPAGQLPRSVDIIADDDLVDKCKPGDRVQIVGIYRCLPSKQGGFTSGTFRTILLANNIKLMSKEIAPTFSADDVAKIKKFCKAHSKDIFEHLSKSLAPSIHGHEYIKKAILCMLLGGNEKVLENGTRIRGDINVLLIGDPSVAKSQLLRYVLHTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIQARLNARCSVLAAANPVYGRYDQYRTPMENIGLQDSLLSRFDLLFIVLDKMDADNDQEIADHVLRMHRYRTPGEQDGYALPLGCSVEIFATDDPNASDVTDQELQIYEKHDNLLHGPRKNKSKIVSMQFIRKYIHVAKLIKPVLTSEAADYISQEYAKIRNHDQINNDSARTMPVTARALETMIRLSTAHAKVRMSKTIERQDAETALELVQFAYFKKVLAKEKKKTDKDLHDENLSQDTLSQESVRKSSRRAGKIADSQDDSMDPYSFSEQDSSLNENLSQSLRPQRKKAESQDGKRSLSQNRTKEFKAALLKAFKSSRSQSVAVSQLLELINKGNPEPFERSEVKEALDNMQNDNQVMVSEDVVFLI UniProtKB

Genomic	tropicalis
Genome Browser	Xenbase	Xenbase JGI Ensembl UCSC	Xenbase

Synteny	Metazome

Expression	tropicalis	laevis
UniGene	Str.4149	Xl.4509 [+] Xl.83343 Xl.83385
Unigene EST Profile	EST Profile	EST Profile
GEO data		GEO
Images	0 expression image(s) for tropicalis and laevis

Orthology	MOD	Entrez Gene	Genetic Phenotypes	Morphants
human	OMIM:Gene, HGNC	MCM3
mouse	MGI	Mcm3	All(4) Targeted, knock Out(1) Gene Trapped(1) Targeted, other(2)
zebrafish	ZFIN	mcm3	6 Lines(s)

Publications
First:		Fission yeast cdc21+ belongs to a family of proteins involved in an early step of chromosome replication. [Nucleic Acids Res 1992]
Most recent:		A large scale screen for neural stem cell markers in Xenopus retina. [Dev Neurobiol 2012]
		View All Papers

Functional Ontologies
GO: Molecular:		ATP binding ATP-dependent DNA helicase activity ATP-dependent RNA helicase activity More[+] ATP-dependent helicase activity ATPase activity ATPase activity, coupled ATPase activity, coupled to transmembrane movement of ions ATPase activity, coupled to transmembrane movement of substances ATPase activity, uncoupled DNA binding DNA translocase activity DNA-dependent ATPase activity RNA-dependent ATPase activity nucleoside-triphosphatase activity nucleotide binding protein-transmembrane transporting ATPase activity single-stranded DNA-dependent ATP-dependent DNA helicase activity
Biological:		DNA replication initiation
Cellular Component:		nucleus
EC:		adenosinetriphosphatase
KOG:		[L] DNA replication licensing factor, MCM3 component

Reagents	tropicalis	laevis
Clones	open biosystems	open biosystems
	geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0	Str.4149.1.S1_at	Xl.4509.1.S1_at
Affymetrix 2.0		Xl2.4509.2.S1_a_at

Symbol legend[+]