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Summary Expression Gene Literature (2) GO Terms (4) Nucleotides (84) Proteins (32) Interactants (35) Wiki
XB-GENEPAGE-5861096
Gene Symbol:
zwilch

Gene Name:
zwilch kinetochore protein

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
Uncharacterized conserved protein

Protein Function :
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and mad1-mad2 complexes onto kinetochores.



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-5861097 XB-GENE-17332295 XB-GENE-5861117
Gene Symbol zwilch zwilch.L zwilch.S
Chromosome Chr03 chr3S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 548970
432018
mRNA RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine zwilch zwilch.L zwilch.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ZWILCH OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Zwilch MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Zwilch Ensembl
zebrafish
ZFIN, AGR zwilch ZFIN Ensembl
chicken
GEISHA ZWILCH Ensembl
fruit fly
FLYBASE Zwilch Ensembl
worm
Publications
First ZW10 links mitotic checkpoint signaling to the structural kinetochore., J Cell Biol 2005                
Most Recent Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly., J Cell Biol 2008                  
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 0 term 4 terms
PANTHER zwilch
KEGG Pathways K11579 K11579
KOG [S] Uncharacterized conserved protein (alt_id KOG:4803)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks zwilch
ORFs zwilch ORF1 zwilch.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience

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