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Summary Expression Gene Literature (0) GO Terms (6) Nucleotides (157) Proteins (31) Interactants (0) Wiki
XB-GENEPAGE- 5863425

Gene Symbol: hdac8

Gene Name: histone deacetylase 8

Synonyms:
Add Xenopus synonyms , Nomenclature history

Gene Function: Histone deacetylase complex, catalytic component RPD3

Protein Function:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

Interactants:

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-5863426 XB-GENE-5863488 XB-GENE-17346738
Genome X. tropicalis X. laevis L X. laevis S
Gene Symbol hdac8 hdac8.L hdac8.S
Chromosome Chr08 chr8L
Molecules tropicalis laevis .L laevis.S
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 GBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot Refseq Swiss-Prot
Genomic tropicalis laevis .L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis .L laevis.S
Ensembl Ensembl
UniGene Str.52530 Xl.7001
RNA-seq profile: Owens, Blitz et al. 2016 hdac8
Images 0 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis .L laevis.S
XenMine hdac8 hdac8.L hdac8.S
Phenotype tropicalis laevis .L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards HDAC8 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Hdac8 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN hdac8 ZFIN Ensembl
chicken
GEISHA HDAC8 Ensembl
fruit fly
worm
WORMBASE
Publications
First:
Most recent:
View All Papers
Functional Ontologies tropicalis laevis .L laevis.S
GO 6 terms 6 terms 0 term
EC acetylspermidine deacetylase
PANTHER hdac8
KEGG K11405 K11405
KOG [B] Histone deacetylase complex, catalytic component RPD3
Reagents tropicalis laevis .L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
ORF hdac8 ORF1
Affymetrix 1.0 Str.49307.1.S1_at Xl.7001.1.A1_at
Affymetrix 2.0 Xl2.7001.1.A1_at

Symbol legend[+]

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