Gene Symbol: hdac8 [provisional] Gene Name: histone deacetylase 8 [provisional] Add Xenopus synonyms Gene Function: Histone deacetylase complex, catalytic component RPD3 Interactants:

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001126990|Xenopus (Silurana) tropicalis histone deacetylase 8 (hdac8), mRNA CACAAAAGGGGCGTGGTCAAAAAAATTTGCCAAAGTAAGGGAGTTTTAGTGCGGAATATAAGCTGCTCCATTCATACAGTTTATTGTGGCTGCAGCACATTTTCTCCCTCACTGTTTCCTGTTGGATCGGCACCTGTATGAAACCCAACCCTCCTGATCCTCTCCGACTGGATACACAGTAACAGCGCAGCTATCCACATAAAAGGAAGCAGGAGGTTGGACTAAGCAAGTGCACCCTATACAGCTATAAAGAGTGAGCTCTGGCGCCCCCCTGTGGCGCTGGGCTGAGCGATCCTCACATTGCGGGGAACTATAGGGTCGGAACCATTGAGCGTTTGAATGGTTTTCGGAGGGCTTCTGTGGCACAGAGAAACTTCCGGTCTTGGGCAAAATGGAGGAGTCGCTGCTTCCGGTTTACATTCACAGCGCCGAATATGTCGAATTGTGTGATAATGTGCAGAGCAAAGTGCCCCGGCGGGCCAGCATGGTGCATTCATTAATAGAGGCATATGGGCTGCTCAAAGAGATGAGGGTAGTGAAGCCAAAAGTTGCTTCTATGGAAGAAATGGCTGCATTTCACACTGATTCATATCTCCAGCATCTACATAAAGTCAGCGAGGAGGGCGACAATGATGATCCTGAAACCCTTGAATATGGACTAGGCTATGACTGCCCCATTACTGAAGGAATATATGACTATGCTGCTGCTGTGGGGGGAGCCACCTTAACTGCTGCTGAACAGCTTATGGCAGGCAAAACGCGCATTGCCATAAACTGGCCTGGTGGTTGGCATCATGCAAAGAAAGATGAAGCTTCTGGATTCTGTTACCTTAATGATGCTGTTCTGGGGATCTTGAAACTGCGGGAAAAATTTGACCGGGTGCTGTACGTAGATATGGATTTACATCATGGTGATGGGGTTGAAGACGCTTTTAGTTTCACTTCAAAAGTAATGACTGTTTCTCTTCATAAATTTTCCCCTGGATTTTTTCCTGGTACCGGTGATGTAAGTGACATTGGCCTGGGTAAGGGACGTTACTACAGTGTTAATGTACCATTGCAAGATGGAATACAGGATGAAAAATATTACCAAATCTGCGAGGGTGTCCTAAAAGAGGTTTTCACAACATTTAACCCTGAGGCAGTTGTCCTGCAGTTGGGAGCAGATACAATAGCTGGGGATCCCATGTGTTCCTTTAACATGACACCCCAGGGGATTGGAAAGTGCCTAAAATATGTTCTACAGTGGCAGCTTCCAACACTCATCCTGGGAGGAGGGGGCTACCATCTCCCAAACACAGCTCGTTGCTGGACATACTTGACCGCACTTATAGTTGGCAGAACTTTATCTTCTGAAATCCCAGACCACGAGTTCTTCACAGAATACGGACCTGACTATGTACTAGAGGTTACACCGAGCTGCCGGCCTGACCGCAATGACTCTCAGAAGGTTCAGGAAATCTTACAGTCTATTAAAGGTCACTTGAAACAAGTGGTTTAGAGTGGCGTTTCCCTACAGACAATGTTTTCTCCTGTCGTGTCTCAGTCCGCTGATGCATACTTTGCACGTAAAGACCAAGTGCAGTGTTGTCTGTGTGTATATGATGCCACAGCGCAACATGTCCTACTGCAATCACCCACATTCCTCTACTGTGTGTCCTGTGTGCTCCAAGAATATATATTTTTTAACTTGTTGCTTTTAACTGCTATTTTTAAACGAATATTAAACCATTGTTTATAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001092242|Xenopus laevis histone deacetylase 8 (hdac8), mRNA GAGCAATAAGGATCTTTCTGCAGCTCTGATATAGTGACAGTTTTAGGAGGATAGGAACGATTGTACATCCGTACTGCTTCGGAAGGGAGCTGTGGAACACAGACACTTCTGGTCCCGGGCAACATGGAGGAGTCGCAGCTTCCGGTTTATATACACAGCGCCGAATACGTGGAATTATGTGATAATTTGCTGAGCAAAGTGCCCCGGAGGGCCAGCATGGTGCACTCATTAATCGAGGCATATGGGCTGCTCAAAGAGATGAGGTGAGGTCAGATACTGCCATTATATAAGTCGCTCTCTGAAAGAAATATGTCCAGGGTAGTAAAGCCAAAAGTTGCATCTATGGAAGAGATGGCTGCCTTTCACACTGATGCATATCTCCAGCATCTACATAAAGTCAGTGAGGAAGGCGACAATGATGATCCTGAAACACTTGAATATGGACTAGGTTACGACTGCCCCATTACTGAAGGAATATATGACTATGCTGCTGCTGTGGGGGGAGCCACTTTAACTGCTGCTGAACAGCTTATAGAGGGCAAAACTCGCATTGCTGTCAACTGGCCTGGTGGTTGGCATCACGCAAAGAAAGATGAAGCTTCTGGATTCTGTTACCTTAATGATGCTGTCCTGGGTATTTTGAAACTGCGGGAAAAATTTGACCGGGTTTTGTACGTAGATATGGATTTACATCATGGTGATGGGGTTGAAGACGCTTTTAGCTTCACTTCAAAAGTAATGACTGTTTCTCTCCATAAATTTTCCCCTGGATTTTTTCCTGGCACTGGTGATGTAAGTGACATTGGCCTGGGTAAGGGACGTTACTACAGTATTAATGTGCCATTACAAGATGGAATACAGGATGATAAATATTACCAAATCTGCGAAGGTGTCCTAAAAGAGGTTTTCACAACTTTTAACCCTGAGGCAGTTGTCCTGCAGTTGGGAGCAGATACAATAGCCGGGGATCCCATGTGTTCTTTTAACATGACCCCAGAGGGGATTGGAAAGTGCCTAAAATATGTTCTACAGTGGCAGCTTCCAACACTCATACTGGGAGGAGGGGGCTACCATCTCCCAAACACAGCTCGTTGCTGGACATACTTGACCGCACTTATAGTTGGCAGGACTTTATCTTCTGAAATCCCAGACCACGAGTTCTTCACAGAATACGGACCTGACTATGTATTAGAGATTACACCGAGCTGTCGGCCTGACCGCAATGACACTCAGAAGGTTCAGGAAATCTTACAATCAATTAAAGGTAACTTGAAACGAGTGGTTTAACGTGAGGTTCCCTACAGAGACGGTGGTTTTTCCTATTGTTTCTCAGTCCACTGAAGCATACTTTGCACATAAAAACCAAGTGCAGTGTTGTCTGTGCATATAGGGTGCCACTGCATAGCAACATGTCTTGCTACACTCACCTCCACATTCCTCTACTGTGTGTCCCTTGTGCTCCAAGAAAAAATATATATATATTTTTTTTTTTAACTTGTTGCTTTTAACTGTTGTTTTTAAATGAATATTAAACCATTGTTTATAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001120462|histone deacetylase 8 [Xenopus (Silurana) tropicalis] MEESLLPVYIHSAEYVELCDNVQSKVPRRASMVHSLIEAYGLLKEMRVVKPKVASMEEMAAFHTDSYLQHLHKVSEEGDNDDPETLEYGLGYDCPITEGIYDYAAAVGGATLTAAEQLMAGKTRIAINWPGGWHHAKKDEASGFCYLNDAVLGILKLREKFDRVLYVDMDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDIGLGKGRYYSVNVPLQDGIQDEKYYQICEGVLKEVFTTFNPEAVVLQLGADTIAGDPMCSFNMTPQGIGKCLKYVLQWQLPTLILGGGGYHLPNTARCWTYLTALIVGRTLSSEIPDHEFFTEYGPDYVLEVTPSCRPDRNDSQKVQEILQSIKGHLKQVV UniProtKB	Refseq >NP_001085711|histone deacetylase 8 [Xenopus laevis] MSRVVKPKVASMEEMAAFHTDAYLQHLHKVSEEGDNDDPETLEYGLGYDCPITEGIYDYAAAVGGATLTAAEQLIEGKTRIAVNWPGGWHHAKKDEASGFCYLNDAVLGILKLREKFDRVLYVDMDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDIGLGKGRYYSINVPLQDGIQDDKYYQICEGVLKEVFTTFNPEAVVLQLGADTIAGDPMCSFNMTPEGIGKCLKYVLQWQLPTLILGGGGYHLPNTARCWTYLTALIVGRTLSSEIPDHEFFTEYGPDYVLEITPSCRPDRNDTQKVQEILQSIKGNLKRVV UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.52530	Xl.7001
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	HDAC8
mouse		MGI	Hdac8	All(4) Targeted, knock Out(1) Targeted, other(3)
zebrafish		ZFIN	hdac8	1 Lines(s)

Publications
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Most recent:
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Functional Ontologies
GO: Molecular:		acetylspermidine deacetylase activity histone deacetylase activity
Biological:		histone deacetylation
Cellular Component:		nucleus
EC:		acetylspermidine deacetylase
KOG:		[B] Histone deacetylase complex, catalytic component RPD3

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.49307.1.S1_at	Xl.7001.1.A1_at
Affymetrix 2.0			Xl2.7001.1.A1_at

Symbol legend[+]

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