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Summary Expression Gene Literature (16) GO Terms (12) Nucleotides (261) Proteins (36) Interactants (46) Wiki
XB-GENEPAGE-5865854
Gene Symbol:
smc4

Gene Name:
structural maintenance of chromosomes 4

Synonyms:
xsmc4 , hCAP-C , XCAP-C ( Add synonyms , Nomenclature history )

Gene Function:
Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C)

Protein Function :
Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoi...[+]


InterPro :
SMC hinge sf , RecF/RecN/SMC N , P-loop NTPase , SMC [+]

Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-5865855 XB-GENE-5865892 XB-GENE-17345860
Gene Symbol smc4 smc4.L smc4.S
Chromosome Chr5 chr5L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 100145810
397799
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine smc4 smc4.L smc4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SMC4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Smc4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Smc4 Ensembl
zebrafish
ZFIN, AGR smc4 ZFIN Ensembl
chicken
GEISHA SMC4 Ensembl
fruit fly
worm
Publications
First A heterodimeric coiled-coil protein required for mitotic chromosome condensation in vitro., Cell 1994  
Most Recent Structural basis of HEAT-kleisin interactions in the human condensin I subcomplex., EMBO Rep 2019                    
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 9 terms 7 terms 0 term
PANTHER smc4
KEGG Pathways K06675 K06675
KOG [BD] Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks smc4
Morpholinos (on-target & off-target) smc4 MO1 , smc4 MO2 smc4 MO1 , smc4 MO2
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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