Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (6) GO Terms (16) Nucleotides (212) Proteins (54) Interactants (87) Wiki
XB-GENEPAGE-5914028
Gene Symbol:
birc7

Gene Name:
baculoviral IAP repeat containing 7

Synonyms:
xEIAP , XLX , kiap , livin , mliap , rnf50 , ml-iap , birc7-a , birc7-b ( Add synonyms , Nomenclature history )

Gene Function:
apoptosis inhibitor

Protein Function :
Weak apoptotic suppressor. Has E3 ubiquitin-protein ligase activity. Weak inhibitor of caspase activity.



Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-5914029 XB-GENE-6256117 XB-GENE-5914085
Gene Symbol birc7 birc7.L birc7.S
Chromosome Chr10 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100127811
108702033
398387
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine birc7 birc7.L birc7.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards BIRC7 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Birc7 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Birc7 Ensembl
zebrafish
ZFIN, AGR birc7 ZFIN Ensembl
chicken
GEISHA BIRC7 Ensembl
fruit fly
worm
Publications
First Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition., Nat Cell Biol 2002  
Most Recent Concomitant exposure to benzo[a]pyrene and triclosan at environmentally relevant concentrations induces metabolic syndrome with multigenerational consequences in Silurana (Xenopus) tropicalis., Sci Total Environ 2019  
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 14 terms 3 terms 8 terms
PANTHER birc7
KEGG Pathways K16061 K16061
KOG [DR] Apoptosis inhibitor IAP1 and related BIdomain proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks birc7
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info