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Summary Expression Gene Literature (178) GO Terms (42) Nucleotides (120) Proteins (41) Interactants (325) Wiki
XB-GENEPAGE-5921461
Gene Symbol:
kcnq1

Gene Name:
potassium channel, voltage gated KQT-like subfamily Q, member 1

Synonyms:
kv7.1 ( Add synonyms , Nomenclature history )

Gene Function:
voltage-gated potassium channel activity

Protein Function :
Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon. Associates with KCNE beta subunits that modulates current kinetics. Induces a volta...[+]



Interactants:
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Diseases: 


Disease Ontology:
familial atrial fibrillation [+]

OMIM:
ATRIAL FIBRILLATION, FAMILIAL, 3; ATFB3 [+]

External Links:
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Xenbase Gene ID XB-GENE-5921462 XB-GENE-5921471 XB-GENE-17332712
Gene Symbol kcnq1 kcnq1.L kcnq1.S
Chromosome Chr4 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100145329
373746
108715189
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More.. NCBI Protein TrEMBL
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine kcnq1 kcnq1.L kcnq1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards KCNQ1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Kcnq1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Kcnq1 Ensembl
zebrafish
ZFIN, AGR kcnq1.1 ZFIN Ensembl
chicken
GEISHA KCNQ1 Ensembl
fruit fly
worm
Publications
First Functional expression of two KvLQT1-related potassium channels responsible for an inherited idiopathic epilepsy., J Biol Chem 1998  
Most Recent Molecular Mechanism of Autosomal Recessive Long QT-Syndrome 1 without Deafness., Int J Mol Sci 2021              
All View All Papers 2 paper(s) referencing morpholinos 11 paper(s) referencing OMIMs 15 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 27 terms 20 terms 7 terms
PANTHER kcnq1
KEGG Pathways K04926 K04926 K04926
KOG [P] Voltage-gated K+ channel KCNQ
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks kcnq1
Antibodies Kcnq1 Ab1 , Kcnq1 Ab2 Kcnq1 Ab1 , Kcnq1 Ab2
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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