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Summary Expression Gene Literature (11) GO Terms (13) Nucleotides (238) Proteins (40) Interactants (92) Wiki
XB-GENEPAGE-5936010
Gene Symbol:
nsf

Gene Name:
N-ethylmaleimide sensitive factor

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
vesicle-fusing ATPase

Protein Function :
Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems t...[+]


InterPro :
ATPase AAA core , CDC4 N-term subdom , AAA lid 3 , P-loop NTPase [+]

Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-5936011 XB-GENE-5936105 XB-GENE-17333370
Gene Symbol nsf nsf.L nsf.S
Chromosome Chr10 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 780249
100049722
779070
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine nsf nsf.L nsf.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards NSF OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Nsf MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Nsf Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR nsfb nsfa ZFIN Ensembl
chicken
GEISHA NSF Ensembl
fruit fly
worm
Publications
First An abundant and ubiquitous homo-oligomeric ring-shaped ATPase particle related to the putative vesicle fusion proteins Sec18p and NSF., EMBO J 1990  
Most Recent EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction., Mol Psychiatry 2018              
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 13 terms 6 terms 6 terms
PANTHER nsf
KEGG Pathways K06027 K06027 K06027
KOG [O] AAA+-type ATPase (alt_id KOG:0741)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks nsf
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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