Gene Symbol: tgm2 Gene Name: transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) Synonyms: tg2, tgc, gnah, g-alpha-h Add Xenopus synonyms Gene Function: Interactants: aga(1) , cga(1) , ercc3(1) , ptprd(1) , ptprf(1) , ptpru(1) , rho(1) View All

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		Refseq >NM_001130380|Xenopus (Silurana) tropicalis hypothetical protein LOC100170618 (LOC100170618), mRNA CGGGGAACGGGACCATGGCAGAAGAACTGTATCTAGAGAGCTTTGACCTGGACTGTAGCGGAAATAACCGCAGTCACCGAACCGCAGAAGCCACCTGTGAGCGCCTGATTGTCCGAAGAGGGCAGCCCTTTCAAATAACCCTCAACTTTTCCCCACGGGGTTATGAAGAAGGGGTGGATAAATTGTCGCTCAATGCTGTAACAGGTCCATGTCCCTCGGAAGAATCAGGCACCAGTAACCACATCCCAGTCTCAGATGCTCTGCAAGATGGAGCATGGAGCGCAGCTATTACCAGCACCGATGGCGGCACACTCATCCTTTCTATCACCTCACCCCCGGATGCCCGCATTGGCTACTATAACCTCTCCCTGGAGACCTCCACTGAATACCAAGGCTCCAGCTTTCAGCTTGGAAGTTTCACTCTGCTGTTTAACCCTTGGTGCCCAGAGGATTCTGTCTACTTGGAGACTGAAGAGGAAAGGAAAGAATATGTGCTATGCCAGCATGGGATCATTTTCCAAGGGACAAAGGACTCAGTTGAACATGTTCCCTGGAATTTTGGACAGTTTGAAGATGAGATTCTGGACATCACTCTCCAGGTTTTAGATACCAGCCCTAAGTTCCTAAATGACTCCAACCGTGACTGCTCCAGACGGAATGACCCGGTTTATATCAGTCGTGTGATTAGTGCCATGGTGAACTGTAATGATGACAGAGGGGTTCTCTTTGGACGCTGGGATAACAAATATGATGATGGCATCAGCCCCATGTTTTGGATGGGCAGTGTTGCAATCCTACGCCGCTGGAGGAAATTCAGTTGCCAGGCAGTGAAATATGGCCAGTGTTGGGTGTATGCTGCCGTGGCATGTACAGTATTACGGTGCCTGGGGATTCCAGCCCGGGTAATCACTAACTACAACTCAGCCCATGACACTAACAGCAACCTCCTGATTGAGCAGTACCTGGATGAGCACGGAAAGCGGCAGCCCAAGCAGAAAGAAATAATCTGGAACTATCACTGTTGGACTGAGGCATGGATGACACGTCCAGATTTGGGCGAGGCTTACAATGGATGGCAGGTTGTGGATCCAACACCACAGGAGAAAAGTGAAGGAACCTACTGCTGTGGACCAACTCCTGTGAAAGCTGTTAAGGAAGGAGACCTAAATCTGAAGTATGACGTCCCCTTTGTTTTTGCCGAGGTAAATGCAGATGTGGTCTATTTTGTACAGCAGAACGACGGATCTGTCAAGAAAACCCAATTTATTTCACTGGTGGGTCAGAAGATCAGTACTAAAGCAATCGGAAAAGATGAACGGGAAGACATAACGCTCAACTACAAGTACCCCGAAGGCTCAGAAGATGAAAGACGTGTGTTTGAGAAAGCCAATAAACAATCTGAAGCAGAAGAAGAAAGAGTTGAAACTCCTTCTGATTTCACTATCAAGATTAAAGTCTCTGAAGGGATGAACAAAGGTTCTGACTTTGATGTTTTTGCTGTCATCACCAACAACAGAGAGGAGGAGAAACAGTGCCGCCTCATGTTCTGCGCCCGCACTTGCAGCTACACTGGGGAGGTGGGGCCAGAGTGTGGCATGAAGGACCTTCTCAATCTCACATTGACACCCCAAGAAGAGAAGAGAGTGCCTCTGCGTATCCTATATGAGAAGTATGGCCCCACAATGACTGAGAACAACACGATCAAGCTGGTAGCCATGCTGTACGACTACTCATCTAAGGAGATTATCCTGGCTGTGAGAGACATCCATGTAAAGAATCCAAGCATCAAAATAAAGGTTCTGGGGGAGCCAAAGCAGAAGAGAAAGCTGGTGGCTGAGATCTCCCTAAAGAACCCTCTGGCGGAGCCATTAACAGGCTGCTGCTTCACTGTGGAGGGGGCTGGGCTGACGGCAGAACAACTGGTCAAAACACTTGATTGCCCAGTGGAGCCTGGGCAGGAAGCCAAGGTGAGGGTTGATCTGATGCCCCAGCTAGCCGGTAAGCTCTCTCTGGTTGTGGATTTCGAGAGCGACCTCCTGAAGGCTGTGAAAGGCTACAGGAACATCATCATTGCGCCCCTTCCAAAGTGAGGAGCTAAGGACTTCAGTGGGTGGTTTTCATTTTACTGTCCTAGAATGTGAGCCTTTTGTATTCCTGCGTATATACTATGAACATATCCATGCGCGTTTCTCCATGGCCCTGGAATCAACCTGCTTTTCTCCTTCACCCCCTCCCCCCCCCGCCCCACCCTCGGCACAATGATCTCTGCACAATGATATTTGGTGGTGCAGCCCAATACTGAGCGTCAGCCATCTCTATGCTCCCCTCTCAATGGACTGTCGTTGGCAGGATACAGGAGTCACCCCCAGGACTAAACACCCCCAAACTGAATCTCGGAGAGCTGTACATAACACATTGTATCCTTGTATTAAATGCACTGTTTCTATGAACCCGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001087443|Xenopus laevis protein-glutamine gamma-glutamyltransferase (tgm2), mRNA CTGGGAGATCACTGCTGGAAACGGGACCATGGCAGAAGAATTGTATCTGGAGAGCTTTGACCTGGACTGTAGCGGAAATAACCGCAGTCACCGAACAGCAGAAGCCAGCTGCGAGCAATTGATTGTCCGAAGAGGCCAACCCTTTCAGATAACCCTGAACTTTTCCCCAAGGGGTTATGAAGAAGGAGTGGATAAACTGTCGCTCAATGCTATAACAGGTCCATGCCCGTCTGAAGAATCAGGCACCAGGAGCCATATCCCTGTCTCAGATGCTCTGCAAGATGGAACATGGAGCGCAGCTGTCAAGAGCACGGATGGAGGCACAGTCATTCTTTCTATCACCTCGCCCCCTGACGCCCGTATTGGCGACTATAACTTCACCTTGGAGACCTCCACTGAATCCCAAGGATCCAGTTTCCAGCTTGGAAGTTTCAAACTGCTTTTTAACCCTTGGTGCCCAGAGGACTCTGTATACCTGGAGAATGAAGAAGAAAGAAAAGAATATGTGCTATGCCAGCATGGGATCATTTTCCAAGGGACAAAGGACTCAGTTGAACATGTTCCCTGGAATTTTGGACAGTTTGAAGATGGTATGTTGGAGATTGCTCTCCAGATTTTAGATACCAGCCCTAAGTTCCTAAATGACTCCAACCGTGACTGCTCCCGGCGGAACGACCCGGTGTATATCAGTCGTGTCATTAGTGCCATGGTGAATTGTAATGATGACAAAGGGGTTCTCTATGGACGCTGGGATAACAAATATGATGATGGAGTCAGCCCCATGTTTTGGATGGGTAGTGTCGCAATCTTACGCCGCTGGAGAAAATTTAGTTGCCAGGCTGTGAAATATGGACAATGTTGGGTCTTTGGTGCTGTGGCATGTACAGTATTAAGGTGCCTGGGGATCCCAGCCCGAGTAATCACTAACTACAATTCAGCACATGATACTAACAGCAACCTCCTGATTGAACAGTATCTGGATGAACAAGGGAAGAGGCAGGCGAAGCAGAAAGACATAATCTGGAACTACCACTGTTGGGTGGAGGCATGGATGGGACGTCCAGATCTGGGGGAAGCATACAATGGATGGCAGGTTGTGGATCCAACGCCACAGGAGAAAAGTGAAGGAACATACTGCTGTGGTCCAGCTCCTGTGAAAGCTGTAAAGGAAGGAGACCTGAATCTGAAGTATGATGTCCCCTTTGTTTTTGCGGAGGTAAATGCAGATGTGGCATATTATGTACAGCAGAACGATGGATCTGTCAAGAAAACCCAATTTATTTCACTGGTGGGCCAGAAGATCAGTACTAAAGCAATCGGAAAAGATGAACGGGAAGACATAACTCACAACTACAAGTACCCTGAGGGCTCAGAAGATGAAAGGCGTGTGTTTGAAAAAGCCAATAAACAATTTGGAGAAGGAGAAGTCAATGAAAAATCTCTTGATGTTTCTATTGAGATTAAAGTCTCTGAGGGGATGAACAAAGGCTTTGACTTTGACGTTTTTGCTGTCATCACCAATAACACAGAGGCGGAGAAACAGTGCCGCCTCATGTTCTGCGCCCGCACCAGCAGCTACAATGGAGAGGTGGGACCAGAATGTGGCATGAAGGACCTTCTCAATGTCACATTACCACCCCAGGAAGAGAAGAGGGTGCCTCTGCGTATCCTGTATGAGAAGTATGGCCCCACGATTACTGACAACAATATGATCAAGCTGGTAGCCATGCTGTTTGACTACTCATCTAAGGACATTATCCTGGCTATGCGAGATATCCATATTAAGAATCCAAGCATCAAAATAAAGATTCTGGGGGAGCCCAAGCAGAAGAGAAAGCTGGTGGCTGAGATTTCTCTAAAGAATCCTCTGGCCGAGCCACTGACAGACTGCTGCTTCACTGTGGAGGGGGCTGGGCTGACAGCAGAGCAACTGGTCCAAACACTTGATTGCCCCGTGGAGCCTGGGCAAGATGCCAAGGTGAGAGTCGATCTAATGCCCCAGCTACCCGGCAAGCTCAGTTTGGTAGTGAATTTCGAGAGCGACCTCCTGAAAGCCGTGAAAGGCTACAGGAACATCATCATTGCACCTCTTCCAAAGTGAGAACCGGAGGACTGTGGTGGAGTGGTTTCATATTACTGTCCTAGAATGTGAGCCTTTTATATTCCTGCATATATACAATCAACATATCCATGTGCATTTCTCTGTGGCCCTGGAACCTGCTTTTTTTCCCCTTCACTGCCCCTCAACCTTGGCAGGATGATCTCTGCAAAATGTTATTTGGTGGCACGGTCTATACGGTCATTAAACCCTAATACTGAGTGTCAGACATCTCTGTGCTCTCCCAATGGACTGTGTTGGCAGTATACAGGAGTCAAGTTATCTCCAGGACTAAACACCACCAAACTGAATATTGGAGAGCTGTAAATAACACATTGTATTCATGTATTAAAATCACTGCTTCTACGAGTGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA		Refseq >NM_001091941|Xenopus laevis transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) (tgm2), mRNA CCATGGCAGAAGAATTGTTTCTGGAGAGCTTTGACCTGGACTGTAGTGGAAATAACCGCAGTCACCGAACCGCAGAAGCCAGCTGCGAGCGTCTGATTGTCCGGAGAGGCCAGCCCTTTCAAATAACCCTGAACTTTGCCCCACGGGGCTATGAAGAAGGGGTGGATAGATTGTCACTCAATGCTATAACAGGTCCATGCCCCTCTGAAGAATCAGGCACCAGTAATAATTTCCCAGTCTCGGATGCTCTGCAAGATGGAGCATGGAGCGCAGCTATCAACAGCACTGATGGAGGCACAGTCATTCTTTCTATCACCTCGCCCCCTAATGCCCGCATTGGCTACTATAACCTCAGCTTGGAGACCTCCACTGAATACCAAGGATCCAGCTTCCAGCTTGGAAGTTTCACACTGCTGTTCAACCCATGGTGCCCAGAGGACTCTGTATACCTGGAGAAAAAAGACGAAAGAAAAGAATATGTACTATGCCAGCATGGGATCATTTTCCAAGGGACAAAGAACTCAACTGATCATGTTCCCTGGAATTTTGGACAGTTTGAAGATGGGATTTTGGAGATTGCTCTTCAGATTTTAGATACCAGCCCCAAGTTCCTAAATGACTCCAACCGGGACTGCTCCCGACGGAACGACCCGGTGTATATCAGTCGTGTGATTAGTGCCATGGTGAACTGTAATGACGACAAAGGGGTTCTCTATGGACGCTGGGATAACAAATATGATGATGGAGTCAGCCCCATGTTTTGGATGGGAAGTGTCGCAATCTTACGCCGCTGGAAGAAATTTGGTTGCCAGGCAGTAAAATATGGGCAGTGTTGGGTCTTTGCTGCTGTGGCATGTACAGTATTACGGTGCCTGGGAATTCCAGCCCGGGTCATCACTAACTACAACTCAGCACATGACACAAACAGCAACCTCCTAATTGAACAGTACCTGGATGAACATGGGAAGAGGCAGTCAAAGCAGAAAGACTTAATCTGGAACTACCACTGTTGGGTGGAGGTGTGGATGGCACGTCCAGATCTGGGCGAGGATTACAATGGATGGCAGGTTGTGGATCCAACTCCACAGGAGAAAAGTGAAGGAACATACTGCTGTGGCCCGGCTCCTGTGAACGCTGTGAAGGAAGGAGACCTGAATGTGAAATATGATGTCCCCTTTGTTTTTGCGGAGGTAAATGCAGATGTGATGTATTATGTACAACAGAACGATGGATCTGTCAAGAAAACCCATTCTATTTCACTGGTGGGTCAGAATATCAGCACTAAAGCGATTGGAAAAGATGAACGAGAAGACATAACTCACAACTACAAGTACCCTGAGGGCTCACAAGATGAAAGGCGTGTGTTTGAGAAAGCCAACAAACAATTTGTAGAAGCAGAAGAAGAAGAGGAAAAACCTCTCGATGTCACCATCAAGATTAAAGTCTCTGAGGGGATGAACATAGGCTCTGACTTTGATGTTTTTGCTGTGATCACTAATAACACAGAGGATGAGAAAAAGTGCCGCCTTATGTTCTGTGCTCGCACCACCAGCTACAATGGAGAAGTGGGACCAGAATGTGGCATGAAAGACCTTCTCAATCTCACATTGCCGCCCCAGGAAGAGAAGAGGGTGCCTCTGCATATCCAGTATGAGAAGTACGGCCCCACGATAACCGAGAACAACATGATCAAGCTGGTAGCCATGCTGTACGATTACTCTTCTAAGGACATTATCTTGGCCATGAGAGACATCCATATTAAGAATCCAAGCATCAAAATAAAGATTCTGGGGGAGCCCAAGCAGAAGAGGAAGCTGGTGGCTGAGATTTCTTTAAAGAATCCTCTGGCCGAGCCACTGACAGGCTGCTGCTTCACAGTGGAGGGGGCCGGGCTGACAGCAGAGCAACTGGTCCAAACTCTTGATTGCCCCATTGAGCCTGGGCAGGAAGCCAAAGTGAGAGTTGATCTAATGCCCCAGCTACCCGGTAAGCTCAGTCTGGTAGTGGATTTCGAGAGTGACCTCCTAAAAGCAGTGAAAGGCTACAGGAACATCATCATTGCACCCCTTCCAAAGTGAGAGCCGAAGCACTGCGGTGGGGTGGTTTCATATTACTGTCCTTGAATGTGAGCCTTTTGTATTCCTGCGTATACACAATCAACATATTCCATGCACATTTCTCTGTGGCCCTGGAGCTTGGAATGAAGCTGCTTTTTTCCCTTCTCCCTCAGCAGGATGAGGTCTGCACAATATTTGATGTTGCAGCCCATACTGTCATTAAGCCCCAATACTGTCAGCCATCGCTCTGCTCAGATCCACTCTCAATGGACTGGGTGTTGCCAGTATACGGGAGTCGAGTTACCTCCAGGACTAAACACCACCAAACTGAAACTCAGAGCTGTAAATAACACATTGTACCCATGTATTAAAAGCACTGTTTCTATGAAAAAAAAAAAAAAA
Protein		Refseq >NP_001123852|transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) [Xenopus (Silurana) tropicalis] MAEELYLESFDLDCSGNNRSHRTAEATCERLIVRRGQPFQITLNFSPRGYEEGVDKLSLNAVTGPCPSEESGTSNHIPVSDALQDGAWSAAITSTDGGTLILSITSPPDARIGYYNLSLETSTEYQGSSFQLGSFTLLFNPWCPEDSVYLETEEERKEYVLCQHGIIFQGTKDSVEHVPWNFGQFEDEILDITLQVLDTSPKFLNDSNRDCSRRNDPVYISRVISAMVNCNDDRGVLFGRWDNKYDDGISPMFWMGSVAILRRWRKFSCQAVKYGQCWVYAAVACTVLRCLGIPARVITNYNSAHDTNSNLLIEQYLDEHGKRQPKQKEIIWNYHCWTEAWMTRPDLGEAYNGWQVVDPTPQEKSEGTYCCGPTPVKAVKEGDLNLKYDVPFVFAEVNADVVYFVQQNDGSVKKTQFISLVGQKISTKAIGKDEREDITLNYKYPEGSEDERRVFEKANKQSEAEEERVETPSDFTIKIKVSEGMNKGSDFDVFAVITNNREEEKQCRLMFCARTCSYTGEVGPECGMKDLLNLTLTPQEEKRVPLRILYEKYGPTMTENNTIKLVAMLYDYSSKEIILAVRDIHVKNPSIKIKVLGEPKQKRKLVAEISLKNPLAEPLTGCCFTVEGAGLTAEQLVKTLDCPVEPGQEAKVRVDLMPQLAGKLSLVVDFESDLLKAVKGYRNIIIAPLPK	Refseq >NP_001080912|protein-glutamine gamma-glutamyltransferase [Xenopus laevis] MAEELYLESFDLDCSGNNRSHRTAEASCEQLIVRRGQPFQITLNFSPRGYEEGVDKLSLNAITGPCPSEESGTRSHIPVSDALQDGTWSAAVKSTDGGTVILSITSPPDARIGDYNFTLETSTESQGSSFQLGSFKLLFNPWCPEDSVYLENEEERKEYVLCQHGIIFQGTKDSVEHVPWNFGQFEDGMLEIALQILDTSPKFLNDSNRDCSRRNDPVYISRVISAMVNCNDDKGVLYGRWDNKYDDGVSPMFWMGSVAILRRWRKFSCQAVKYGQCWVFGAVACTVLRCLGIPARVITNYNSAHDTNSNLLIEQYLDEQGKRQAKQKDIIWNYHCWVEAWMGRPDLGEAYNGWQVVDPTPQEKSEGTYCCGPAPVKAVKEGDLNLKYDVPFVFAEVNADVAYYVQQNDGSVKKTQFISLVGQKISTKAIGKDEREDITHNYKYPEGSEDERRVFEKANKQFGEGEVNEKSLDVSIEIKVSEGMNKGFDFDVFAVITNNTEAEKQCRLMFCARTSSYNGEVGPECGMKDLLNVTLPPQEEKRVPLRILYEKYGPTITDNNMIKLVAMLFDYSSKDIILAMRDIHIKNPSIKIKILGEPKQKRKLVAEISLKNPLAEPLTDCCFTVEGAGLTAEQLVQTLDCPVEPGQDAKVRVDLMPQLPGKLSLVVNFESDLLKAVKGYRNIIIAPLPK		Refseq >NP_001085410|transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) [Xenopus laevis] MAEELFLESFDLDCSGNNRSHRTAEASCERLIVRRGQPFQITLNFAPRGYEEGVDRLSLNAITGPCPSEESGTSNNFPVSDALQDGAWSAAINSTDGGTVILSITSPPNARIGYYNLSLETSTEYQGSSFQLGSFTLLFNPWCPEDSVYLEKKDERKEYVLCQHGIIFQGTKNSTDHVPWNFGQFEDGILEIALQILDTSPKFLNDSNRDCSRRNDPVYISRVISAMVNCNDDKGVLYGRWDNKYDDGVSPMFWMGSVAILRRWKKFGCQAVKYGQCWVFAAVACTVLRCLGIPARVITNYNSAHDTNSNLLIEQYLDEHGKRQSKQKDLIWNYHCWVEVWMARPDLGEDYNGWQVVDPTPQEKSEGTYCCGPAPVNAVKEGDLNVKYDVPFVFAEVNADVMYYVQQNDGSVKKTHSISLVGQNISTKAIGKDEREDITHNYKYPEGSQDERRVFEKANKQFVEAEEEEEKPLDVTIKIKVSEGMNIGSDFDVFAVITNNTEDEKKCRLMFCARTTSYNGEVGPECGMKDLLNLTLPPQEEKRVPLHIQYEKYGPTITENNMIKLVAMLYDYSSKDIILAMRDIHIKNPSIKIKILGEPKQKRKLVAEISLKNPLAEPLTGCCFTVEGAGLTAEQLVQTLDCPIEPGQEAKVRVDLMPQLPGKLSLVVDFESDLLKAVKGYRNIIIAPLPK

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene		Str.16090	Xl.21563		Xl.2480
Unigene EST Profile		EST Profile	EST Profile		EST Profile
GEO data			GEO		GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	TGM2
mouse		MGI	Tgm2	All(6) Targeted, knock Out(3) Targeted, other(3)
zebrafish		ZFIN ZFIN	tgm2b tgm2a	1 Lines(s)

Publications
First:		The time of origin of the mesencephalic trigeminal neurons in Xenopus. [J Comp Neurol 1979]
Most recent:		Identification of four single nucleotide polymorphisms in DNA repair genes: XPA and XPB (ERCC3) in Polish population. [Hum Mutat 2000]
		View All Papers

Functional Ontologies
GO: Molecular:		protein-glutamine gamma-glutamyltransferase activity
Biological:		peptide cross-linking
Cellular Component:
EC:		protein-glutamine g-glutamyltransferase
KOG:

Reagents		tropicalis	laevis a		laevis b
Clones		open biosystems	open biosystems		open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0		Str.6049.1.A1_at [+] Str.16090.1.A1_at	Xl.21563.1.S1_at		Xl.2480.1.A1_at
Affymetrix 2.0			Xl2.21563.1.S1_at		Xl2.2480.1.S1_at

Symbol legend[+]

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