Gene Symbol: igf1 Gene Name: insulin-like growth factor 1 (somatomedin C) Synonyms: IGF-I, Somatomedin, xigf1, igf-1, somatomedin-C Add Xenopus synonyms Gene Function: growth factor Interactants: ins(67) , igf2(8) , insr(8) , mapk1(8) , akt1(7) , pik3ca(7) , sgk1(7) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >XM_002936829|PREDICTED: Xenopus (Silurana) tropicalis insulin-like growth factor I-A-like (LOC100486334), mRNA AACTTTGCCAGAAGAGGGAGAGAGAGAGAAGGGAACTATTCTCCCAGCTGTTTCCTGTCTACAGTGTCTGTGTAAATGTAGATAAATGTGAGGCTTTTCTGTAAATCCCTCTTCTGTTTGCAAAATCTGACTGTCACTGCTAAAATCAGAGCAGATAGTCTACGCAATGGAACAAAGTCCTCTATATTGAAATGTGACATTGCTCTGAACATCTCCACTGGATTCCTCTTATTATCACAGCTGACAATTCCATTCCCAGTCTCTGCTCCTAAGAAGCCATGGAAAAAAACAACAGTCTTTCAACACAATTATTTAAGTGCTACTTTTGTGATTTCTTAAAGCTGAAGATGCACAAAATGTCCTACATTCATCTGCTCTACCTGGCTTTGTGTTTCCTGACTTTAACCCATTCAGCAGCTGCTGGACCAGAGACCCTCTGTGGAGCCGAACTGGTAGACACTCTTCAGTTTGTATGTGGAGACAGAGGCTTCTATTTTAGCAAGCCAACAGGGTACGGATCCAGCAATCGAAGATCGCATCACAGAGGAATAGTAGATGAGTGCTGTTTCCAAAGCTGTGATTTCAGAAGGCTGGAGATGTACTGCGCTCCTGCCAAGCCAGCCAAATCAGCACGTTCTGTACGTGCTCAACGTCACACTGACATGCCAAAAGCCCAGAAGGAAGTACACCTAAAGAATGCAAGTCGAGGAAACACAGGGAGTCGAGGATTCCGAATGTAAATGCTGCCACTAAAAGTCTCAGAGTATGAATGTACCATCTGCAGGATACTTTTACTGTATGGAAAAGAAACAAAAAAAACAGTGGAAGATATCAAACATTGTCTGACTATGAACAAGCTTGACAACATCTCAACCAATGGGCATTCTCCCTCTAAACGAATCAAATACACATTCCAATGTTAAAAAACATTCTTGCCAGCT	Refseq >NM_001163393|Xenopus laevis insulin-like growth factor 1 (somatomedin C) (igf1), mRNA AACTTTGCCAGAAGAGGGAGAGAGAGAGAAGGCAAATGCTCCCCCAGCTGTTTCCTGTCTACAGTGTCTGTGTAATGTAGATAAATGTGAGGATTTTCTCTAAATCCCTCTTCTGTTTGCTAAATCTCACTGTCACTGCTAAAATCAGAGCAGATAGTCTACGCAATGGAACAAAGTCCTCTATATTGAAATGTGACATTGCTCTGAACATCTCCACTGGATTCCTTTTATTATCACAGCTGACCATTCCATTCCCAGTCTCTGCTCTCCTCAGAAGCCATGGAAACAAACAACAATCTTTCAACACAATTATTTAAGTGCTACTTTTGTGATATCTTAAAGCTGAAGATGCACAAAATGTCCTGCATTCATCTGCTCTACCTGGTTTTGTGTTTCCTGACTTTAACCCATTCAGCAGCTGCTGGACCAGAGACCCTCTGTGGTGCTGAACTGGTAGACACTCTTCAGTTTGTCTGTGGAGACAGAGGCTTCTATTTTAGCAAGCCAACAGGGTACGGATCCAACAATCGAAGATCGCATCACAGAGGAATAGTAGATGAGTGCTGTTTCCAAAGCTGTGATTTCAGAAGGCTAGAGATGTACTGCGCTCCAGCCAAGCCAGCCAAATCAGCACGTTCTGTACGTGCTCAACGTCACACTGATATGCCAAAAGCCCAGAAGGAAGTACACCCGAAGAATACAAGTCGAGGAAACACAGGAAGTCGAGGATTCCGAATGTAAATGCTGCCACTAAAAATCTTGGAGTATGAATGTACCATCTGCAGGATACTTTTACTGTATGGAAAAGGAACAAAAAACAGTGGAAGATATCAAACAATTATCTGACTATGAACAAGTTTTAACAACATCTCAACCAATGGGCATTCTCCCTCTAAACAATTCAAATACACATTCCAATGTTATAAACATTCTTGCCAGCT
Protein		NCBI Protein >XP_002936875|PREDICTED: insulin-like growth factor I-A-like [Xenopus (Silurana) tropicalis] MEKNNSLSTQLFKCYFCDFLKLKMHKMSYIHLLYLALCFLTLTHSAAAGPETLCGAELVDTLQFVCGDRGFYFSKPTGYGSSNRRSHHRGIVDECCFQSCDFRRLEMYCAPAKPAKSARSVRAQRHTDMPKAQKEVHLKNASRGNTGSRGFRM	Refseq >NP_001156865|insulin-like growth factor I-A precursor [Xenopus laevis] METNNNLSTQLFKCYFCDILKLKMHKMSCIHLLYLVLCFLTLTHSAAAGPETLCGAELVDTLQFVCGDRGFYFSKPTGYGSNNRRSHHRGIVDECCFQSCDFRRLEMYCAPAKPAKSARSVRAQRHTDMPKAQKEVHPKNTSRGNTGSRGFRM UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC
Synteny		Metazome

Expression		tropicalis	laevis
UniGene			Xl.23602
Unigene EST Profile			EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	IGF1	OMIM:608747
mouse		MGI	Igf1	All(12) Targeted, knock Out(7) Targeted, other(5)
zebrafish		ZFIN	igf1

Publications
First:		Nucleotide sequence and expression of a cDNA clone encoding a fetal rat binding protein for insulin-like growth factors. [J Biol Chem 1989]
Most recent:		Xenopus laevis insulin receptor substrate IRS-1 is important for eye development. [Dev Dyn 2011]
		View All Papers 6 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		hormone activity
Biological:		physiological process
Cellular Component:		extracellular region
EC:
KOG:

Reagents		tropicalis	laevis
Clones			EXRC - 1 clone(s)
			open biosystems
			geneservice/RZPD imagenes
Affymetrix 1.0		StrEns.5158.1.S1_at	Xl.23602.1.S1_at
Affymetrix 2.0			Xl2.23602.1.S1_at

Symbol legend[+]

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