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Summary Expression Gene Literature (31) GO Terms (3) Nucleotides (193) Proteins (31) Interactants (196) Wiki
XB-GENEPAGE-977813
Gene Symbol:
spr

Gene Name:
sepiapterin reductase

Synonyms:
xspr ( Add synonyms , Nomenclature history )

Gene Function:
Predicted dehydrogenase

Protein Function :
Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
sepiapterin reductase deficiency

OMIM:
DYSTONIA, DOPA-RESPONSIVE, DUE TO SEPIAPTERIN REDUCTASE DEFICIENCY

External Links:
 
Xenbase Gene ID XB-GENE-977814 XB-GENE-6253916 XB-GENE-17339198
Gene Symbol spr spr.L spr.S
Chromosome Chr01 chr1L
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100145068
380273
mRNA RefSeq RefSeq
Protein RefSeq RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine spr spr.L spr.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SPR OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Spr MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Spr Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR sprb spra ZFIN Ensembl
chicken
GEISHA SPR Ensembl
fruit fly
FLYBASE FLYBASE FLYBASE SPR Spread-d sprw Ensembl
worm
Publications
First Attenuation of agonist-induced desensitization of the rat substance P receptor by progressive truncation of the C-terminus., FEBS Lett 1994  
Most Recent Disruptive effects of two organotin pesticides on the thyroid signaling pathway in Xenopus laevis during metamorphosis., Sci Total Environ 2019  
All View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 3 terms 3 terms 0 term
PANTHER spr
KEGG Pathways K00072 K00072
KOG [Q] Predicted dehydrogenase
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks spr
ORFs spr.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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