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Summary Expression Gene Literature (22) GO Terms (11) Nucleotides (181) Proteins (28) Interactants (108) Wiki
XB-GENEPAGE- 953945

Gene Symbol: fbxo5

Gene Name: F-box protein 5

Synonyms: emi1 , fbx5 , fbxo5-b , fbxo5-a
Add Xenopus synonyms , Nomenclature history


Gene Function:

Protein Function:
Regulates progression through early mitosis by inhibiting the anaphase promoting complex/cyclosome (APC). Binds to the APC activators cdc20 and fzr1/cdh1 to prevent APC activation. Can also bind direct...[+]


Interactants: YYY

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-953946 XB-GENE-6255898 XB-GENE-953951
Gene Symbol fbxo5 fbxo5.L fbxo5.S
Chromosome scaffold_5 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.44195 Xl.39598 Xl.11644
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 0 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine fbxo5 fbxo5.L fbxo5.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards FBXO5 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Fbxo5 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN fbxo5 ZFIN Ensembl
chicken
GEISHA FBXO5 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. [Cell 2001]
Most recent: Maternal Dead-End1 is required for vegetal cortical microtubule assembly during Xenopus axis specification. [Development 2013]
View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 11 terms 9 terms 9 terms
EC
PANTHER fbxo5
KEGG Pathways K10292 K10292 K10292
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
ORF fbxo5 ORF1 fbxo5 ORF2
Affymetrix 1.0 Str.10791.1.S1_at [+] Xl.11644.1.S1_at
Affymetrix 2.0 Xl2.39598.1.S1_at Xl2.11644.1.S1_s_at

Symbol legend[+]

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