rps6ka6 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (3)

Nucleotides (111)

Interactants (6)

XB-GENEPAGE-487732

Gene Symbol: rps6ka6 Gene Name: ribosomal protein S6 kinase, 90kDa, polypeptide 6 Synonyms: rsk4, pp90rsk4 Add Xenopus synonyms Gene Function: serine/threonine kinase Interactants: ikzf1(2) , kcnn4(2) , arfgap1(1) , mapk1(1) , rps6ka1(1) , rps6ka3(1) , View All

XB-GENE-487733

XB-GENE-6487851

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >XM_002938544\|PREDICTED: Xenopus (Silurana) tropicalis ribosomal protein S6 kinase alpha-6-like (LOC100488417), mRNA CGCTGATAGCTTGCTGGATAGGAGCTCTCTGTAGCAGGAAGCAGGGGAGATTAAAAAGGCCAAAGTGTGCTATAGAGGGAACAGCCTGGGCAGGGTGCTTGTGAGATTCCCCGCAGGCACGCCTTTTTTTCTTTCTTTGTTGCTGTTGCTTTAAGAACTCTTGCTGATTTCTTCTTCGCCACTGCTGTGCTTATCACAGGAGCGCACCTCTTCCTGCATTGCCTAGCAACCGGACTCACCGCCTCCTCAGAAGGAGGGGAGCCGGCTTCTTCACACAGCACACTCTGCTCTCCGGTCTGCTGACACAGCGCTGCAATCCAAGCACGATCGTCATGGCCCGCCTTTTCCAACCATTGCAGGACGTGCTGTAGGGAGATGGGGTCTTGCACTGCCATTGCTGTTCCTCCAACGCCCCCTCGCCGAGTCCCCTGCTCCGTTCAGGCACTTCAGTTCTCCTCTTCACCGCTGGAAGCGCTCCTGGATGTCAGGCTGCACTGCTCCCGGATCCCCTAAACGCTCATCCCCCCCCTTCTGGGTGCCTTTCTCTGTCCTGAGAGGAGCAGGCGGGTCATGCCTGGACCAAACCACCTGTGAAAGAAGGGGTGTTGTGGGGATGCCGCAGCGGCTCAGCCAACTGGAGAATCCGTGGCAGAAAATGGAGGTGTATGTGACCGGCAGCAGCGAGTTAAATGGATTGAAGATGATGGATGAGCCAATGGAGGAAGGGGAGTCTTTATTACCTTATGTAAATTTCACACAGACTTTTTTTATGCTATTAAAGAGGGCCTCATTTAAAGTAAGAGACAGAGTACGGACAAAGATGGAGAGAGATATCCTTGTGGAAGTTAACCATCCATTTATTGTGAAGTTGCACTACGCCTTTCAAACAGAAGGGAAGTTATATCTGATTCTGGATTTTCTCAGGGGAGGAGATGTATTCACGCGGTTATCCAAAGAGGTTATGTTTACAGAGGAAGATGTGAAGTTTTACCTGGCAGAACTGGCTCTTGCTTTGGACCATCTTCACAGCTTGGGAATCGTGTACAGAGATCTGAAACCAGAAAACATTTTGCTTGATGAAGCAGGACATATCAAGTTAACAGACTTTGGCCTCAGTAAAGAATCGGTGGATCATGAAAAAAAAGCCTATTCATTCTGTGGTACAGTAGAGTATATGGCACCAGAAGTTGTAAACCGGCGAGGTCACACACAAAGTGCTGACTGGTGGTCTTTTGGTGTTCTAATGTTTGAGATGCTCACTGGTACATTGCCTTTCCAAGGCAAAGATCGGAATGAAACAATGAATATGATTCTTAAATCAAAGCTTGGGATGCCACAATTTTTAAGCCCTGAAGCCCAAAGCCTGCTGAGGATGTTGTTTAAAAGAAATCCTTCAAATAGATTAGGTGCTGGCTTGGATGGTGTTGAAGAAATCAAGCGACATCCATTTTTTTCAACTATTGATTGGAATAAGTTGTATAGGCGTGAAATACAGCCCCCATTTAAACCTGCATCCGGAAAGCCAGAGGACACTTTTTGCTTTGATCCGGAGTTTACAGCAAAAACACCTAAAGATTCTCCGGGAGTTCCACCCAGTGCTAATGCCCATCAGCTTTTTAAAGGCTTTAGCTTTGTTGCTCCGTCTTCTGTTGAAGAACATAAGATTTCTTCTATTGCAAATGTCTTGCCAATTGTACAGCAATTCCATGGAAGCAGAGCTCAATTTACAGATGTTTACGATCTTAAAGAAGATATTGGTGTTGGTTCCTATTCTGTATGCAAACGCTGTGTCCACAGGGCAACAAATATGGAGTTTGCTGTTAAGATCATCGATAAAAGTAAGAGAGATCCATCCGAAGAGATCGAAATTCTTATGCGTTATGGACAGCATCCAAACATTATTACATTAAAAGATGTGTACGACGACAATGGCAGATATGTTTATCTCGTTACTGAGCTGATGAAAGGAGGAGAATTGCTCGATCGGATACTCAGGCAGAAATATTTTTCAGAACGTGAAGCCAGTGCTGTGCTGTACACCATCACCAAAACTGTAGACTACTTGCACTGTCAAGGAGTGGTTCACCGTGACCTTAAACCCAGCAACATTCTTTATATGGATGACTCAAGCAATGCAGACTCTATACGAATATGTGATTTTGGATTTGCCAAGCAATTGCGGGGAGACAATGGCCTGCTTTTGACACCATGTTACACTGCCAATTTTGTGGCGCCAGAGGTTCTAATGAGGCAAGGATATGATGCTGCATGTGATATCTGGAGCCTAGGGGTCCTGCTGTATACAATGTTGGCAGGATATACACCTTTTGCCAATGGACCCAATGATACCCCTGAGGAAATCTTACTGCGGATAGGCAGTGGAAACTTCTCACTTAGTGGAGGGAACTGGGACACTGTTTCAGATGCTGCAAAGGACTTGTTATCCCATATGCTTCATGTTGATCCTCATCAGCGATATACAGCTGAGAAAGTATTAAAACATTCCTGGATTGCATGTAGAGATCAGCTTCCACATTACCAACTGAACAGACAAGATGCACCTCATCTCGTGAAGGGAGCAATGGCTGCAACATATTCTGCTCTGAATCAGAAGACGTTTCAACCCATTCTAGAACCTGTTGCAGCCTCCAACTTAGCACAGCGTCGCAGTATGAAAAAGAGAACGTCAACGGACTTGTAG	Refseq >NM_001091841\|Xenopus laevis ribosomal protein S6 kinase, 90kDa, polypeptide 6 (rps6ka6), mRNA CAGACACGAAGGAGTGTACATTAAAGGAGAAACACAAGGCGCTATAGTGGGATAAAGCACCGGCTGCGTAGACACCACGTATAAGGAACATTTATCGATAGTAACTTAAACAGTGACTGAAGGCTGGAGCGTTGACATTTAATAATTTTACATTAAAAACGTGGAGTGCCGCCGCTGTGTCTCTGCTTGACGTTGTGCAGCACCTGAGACAACGCTTTGAGGATGCCGCTGGCACAGCTGGTGAATCTTTGGCCCGAGGTTGCGGTGGTTCATGAGGACCCGGAGAATGGACATGGCAGTCCAGAAGAAGGTGGACGGCATACCTCTAAGGATGAGGTGGTGGTTAAAGAATTCCCGATCACTCATCATGTTAAAGAAGGTTCGGAGAAGGCCGATCAGTCAGATTTTGTTTTACTCAAAGTCTTAGGACAGGGCTCTTTTGGGAAGGTTTTCCTGGTCCGGAAAATAACGCCACCTGATGCCAACCAGCTCTATGCTATGAAAGTGCTGAAAAAGGCCACACTCAAAGTGCGTGACCGAGTTAGAACCAAGATGGAGCGAGATATTCTAGCTGATGTGCACCATCCCTTTGTTGTAAGGCTACACTATGCTTTTCAGACTGAGGGGAAACTTTACTTAATCCTGGATTTTCTGCGGGGAGGAGATCTATTTACACGTCTGTCCAAAGAGGTGATGTTCACAGAAGAAGATGTGAAGTTTTACCTAGCTGAATTGGCTTTGGGTCTTGATCATTTGCACAGCCTAGGGATCATCTACCGTGACCTAAAACCTGAAAACATTCTCTTGGACGAAGAGGGCCATATAAAGCTTACTGATTTTGGACTTAGTAAAGAAGCAATAGACCATGAAAAAAAGGCTTATTCTTTTTGTGGGACTGTGGAATACATGGCTCCTGAAGTGGTGAATCGACAGGGACACTCACACAGCGCAGACTGGTGGTCTTATGGCGTGCTCATGTTTGAGATGCTGACAGGATCCCTGCCATTCCAGGGCAAAGACCGTAAGGAAACCATGACTCTAATCCTAAAAGCCAAACTAGGGATGCCTCAGTTTCTTAGCAATGAAGCACAAAGTCTATTACGCGCTCTGTTCAAAAGGAATCCTACTAACCGTTTAGGATCTGCCATGGAAGGGGCTGAAGAGATTAAGCGCCAACCCTTTTTCTCAACCATTGATTGGAATAAATTATTCCGCAGGGAGATGAGCCCACCCTTTAAACCAGCAGTTACCCAGGCAGATGATACCTATTACTTTGACACAGAATTTACATCTCGAACTCCAAAAGACTCTCCTGGTATACCACCTAGTGCTGGAGCCCACCAGCTTTTCCGAGGGTTTAGTTTTGTGGCTCCAGCATTGGTAGAGGAAGATGCAAAAAAAACAAGCAGTCCTCCTGTACTTTCAGTGCCAAAGACACACAGTAAAAATATTCTTTTTATGGATGTGTACACTGTGCGGGAAACTATTGGTGTTGGATCGTACTCTGTGTGCAAGCGATGTGTTCATAAAGGAACCAACATGGAGTATGCAGTAAAGGTTATAGACAAAACAAAGAGAGACCCATCAGAGGAAATTGAGATCTTGAGGCGATATGGGCAGCATCCCAACATCATTGCATTAAAAGATGTTTATAAAGAGGGTAACAGTATCTACGTTGTAACAGAGTTGATGCGAGGTGGGGAGCTCCTGGACCGCATTCTAAGGCAAAAATTCTTCTCTGAAAGAGAAGCCAGTTCTGTCCTTTTTACAGTCTGCAAAACAGTGGAGAATTTACACTCTCAAGGGGTAGTTCATAGAGACCTGAAGCCTAGCAATATTCTGTATGTGGATGAATCAGGTGATCCAGAGTCAATCAGAATATGTGATTTTGGATTTGCTAAACAGCTACGAGCAGATAATGGATTGCTCATGACTCCGTGCTACACAGCCAATTTTGTTGCACCAGAGGTATTGAAGCGACAGGGCTATGATGAGGGCTGTGACATCTGGAGCTTAGGCATTCTCCTTTATACTATGCTTGCAGGTTACACGCCATTTGCAAATGGACTAGGAGACACTCCTGAAGAGATACTAGCTCGTATCGGTAGTGGGAAATTTACACTGAGGGGTGGAAACTGGAATACTGTGTCTGCTGCTGCAAAGGACTTGGTTTCACGAATGCTGCATGTAGACCCTCATAAGAGGCTCACTGCTAAACAAGTTCTACAGCATGAATGGATCACAAAAAGAGACGCGTTACCTCAGAGCCAACTGAACCGACAGGATGTACATCTAGTTAAAGGAGCAATGGCTGCAACATACTCTGCCTTAAACAGCTCCAAGCCGACACCTCTGCTGCAGCCCATTAAATCGTCTATTCTGGCACAGCGGCGGGTCAAGAAGCTGCCTTCTACTACTCTTTAGCTGGAGCCTTGTATAAGGGAATTCTTCCCTCTGTGCATAACTTCTCACAAAAACTTGCCGATACAGCCTTACTTTCCTGTTGTACCTCCTTTGATCCCTATTGCTATGGTAGAAGAATGCCTGGTTCTCCAGCTGATACTTCACACTGTGGTAGGCGGAACTGTGGGGCTGTGTGCTTTGGGCAGCGGTCAAGAAAACATGATTGTATACTTGTAGTGGAAGGTTCCATTCTTCTTGGATACCAATGTGTCCACTGCCATCATATCCTTACATACTGTCAAGCACTATCTCAGGGCTGTCTGTAGTCCTACCTCCTTGACACAGGAAAGTGCTACATTTTATTACTTTGTTGTGGGTCATTTCTTTTGCTTTTTGCTGCATTTACACTAAATTAGCCCATTGTTTTTACACTCCTTTGCAATTACTCTTTCCCATATAATATTTCAGTTATCTGCCATTAGAAAATAATAGGTGCTGCCTTTTGCACACCAAAAGGGCTGTATCCCTTACTGTGTATCCCTTATCAGGTCTATTACAAAGAACGTAATATGTGTTGTGCTACCAAGGGCACTTTAAAAGTTACTATATTAGCCTCACCTCTTACCTGTCAGATTCTCAAACTGTGAATTTGCAAATGAGAATTTTAGAGCTCAAGAAACCAATCTCATGCTTCAGTATCAATAAAAACTGCTGGAATACAGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		NCBI Protein >XP_002938590\|PREDICTED: ribosomal protein S6 kinase alpha-6-like [Xenopus (Silurana) tropicalis] MSGCTAPGSPKRSSPPFWVPFSVLRGAGGSCLDQTTCERRGVVGMPQRLSQLENPWQKMEVYVTGSSELNGLKMMDEPMEEGESLLPYVNFTQTFFMLLKRASFKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIVYRDLKPENILLDEAGHIKLTDFGLSKESVDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRNETMNMILKSKLGMPQFLSPEAQSLLRMLFKRNPSNRLGAGLDGVEEIKRHPFFSTIDWNKLYRREIQPPFKPASGKPEDTFCFDPEFTAKTPKDSPGVPPSANAHQLFKGFSFVAPSSVEEHKISSIANVLPIVQQFHGSRAQFTDVYDLKEDIGVGSYSVCKRCVHRATNMEFAVKIIDKSKRDPSEEIEILMRYGQHPNIITLKDVYDDNGRYVYLVTELMKGGELLDRILRQKYFSEREASAVLYTITKTVDYLHCQGVVHRDLKPSNILYMDDSSNADSIRICDFGFAKQLRGDNGLLLTPCYTANFVAPEVLMRQGYDAACDIWSLGVLLYTMLAGYTPFANGPNDTPEEILLRIGSGNFSLSGGNWDTVSDAAKDLLSHMLHVDPHQRYTAEKVLKHSWIACRDQLPHYQLNRQDAPHLVKGAMAATYSALNQKTFQPILEPVAASNLAQRRSMKKRTSTDL	Refseq >NP_001085310\|ribosomal protein S6 kinase 2 alpha [Xenopus laevis] MPLAQLVNLWPEVAVVHEDPENGHGSPEEGGRHTSKDEVVVKEFPITHHVKEGSEKADQSDFVLLKVLGQGSFGKVFLVRKITPPDANQLYAMKVLKKATLKVRDRVRTKMERDILADVHHPFVVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSNEAQSLLRALFKRNPTNRLGSAMEGAEEIKRQPFFSTIDWNKLFRREMSPPFKPAVTQADDTYYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVAPALVEEDAKKTSSPPVLSVPKTHSKNILFMDVYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVIDKTKRDPSEEIEILRRYGQHPNIIALKDVYKEGNSIYVVTELMRGGELLDRILRQKFFSEREASSVLFTVCKTVENLHSQGVVHRDLKPSNILYVDESGDPESIRICDFGFAKQLRADNGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGLGDTPEEILARIGSGKFTLRGGNWNTVSAAAKDLVSRMLHVDPHKRLTAKQVLQHEWITKRDALPQSQLNRQDVHLVKGAMAATYSALNSSKPTPLLQPIKSSILAQRRVKKLPSTTL UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene			Xl.856 [+] Xl.42153 Xl.19569
Unigene EST Profile			EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	RPS6KA6
mouse		MGI	Rps6ka6	All(3) Targeted, other(1) Targeted, knock Out(1) Gene Trapped(1)
zebrafish

Publications
First:		Molecular and functional characterization of the small Ca(2+)-regulated K+ channel (rSK4) of colonic crypts. [Pflugers Arch 1999]
Most recent:		Characterization of mouse Rsk4 as an inhibitor of fibroblast growth factor-RAS-extracellular signal-regulated kinase signaling. [Mol Cell Biol 2004]
		View All Papers

Functional Ontologies
GO: Molecular:		ATP binding cAMP-dependent protein kinase activity cAMP-dependent protein kinase regulator activity More[+] protein kinase CK2 activity protein kinase CK2 regulator activity protein kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity serine-type endopeptidase inhibitor activity
Biological:		protein amino acid phosphorylation
Cellular Component:		cAMP-dependent protein kinase complex protein kinase CK2 complex
EC:		now divided into EC:2.7.11.1, EC:2.7.11.8, EC:2.7.11.9, EC:2.7.11.10, EC:2.7.11.11, EC:2.7.11.12, EC:2.7.11.13, EC:2.7.11.21, EC:2.7.11.22, EC:2.7.11.24, EC:2.7.11.25, EC:2.7.11.30 and EC:2.7.12.1
KOG:		[T] Ribosomal protein S6 kinase

Reagents		tropicalis	laevis
Clones			open biosystems
			geneservice/RZPD imagenes
Affymetrix 1.0		Str.47422.1.A1_at [+] StrEns.6644.1.S1_at	Xl.856.1.A1_at
Affymetrix 2.0			Xl2.856.1.S1_at [+] Xl2.50607.2.A1_at Xl2.50607.1.S1_at Xl2.19569.1.A1_at Xl2.42153.1.S1_at

Symbol legend[+]