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Summary Expression Gene Literature (5) GO Terms (17) Nucleotides (173) Proteins (31) Interactants (44) Wiki
XB-GENEPAGE-853844
Gene Symbol:
kmt2b

Gene Name:
lysine methyltransferase 2B

Synonyms:
trithorax , hrx2 , mll2 , trx2 , wbp7 ( Add synonyms , Nomenclature history )

Gene Function:
zinc-finger-like PHD finger, transcription factor

Protein Function :



Interactants:
Loading ...

Diseases: 


OMIM:
DYSTONIA 28, CHILDHOOD-ONSET; DYT28

External Links:
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Xenbase Gene ID XB-GENE-853845 XB-GENE-17334205 XB-GENE-6486229
Gene Symbol kmt2b kmt2b.L kmt2b.S
Chromosome scaffold_37 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.1 Version 9.1
CDS Gene model
Entrez Gene 100144721
mRNA NCBI Nucleotide
Protein NCBI Protein NCBI Protein
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine kmt2b kmt2b.L kmt2b.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards KMT2B OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Kmt2d MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Kmt2b Ensembl
zebrafish
chicken
fruit fly
worm
Publications
First WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development., Cell 2005    
Most Recent The B-subdomain of the Xenopus laevis XFIN KRAB-AB domain is responsible for its weaker transcriptional repressor activity compared to human ZNF10/Kox1., PLoS One 2014              
All View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 0 term 0 term
PANTHER kmt2b
KEGG Pathways K01327 [+]
KOG [K] Transcription factor TCF20
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks kmt2b
Clones Horizon Source BioScience Source BioScience
Plasmids Addgene Addgene

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