Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (6) GO Terms (17) Nucleotides (79) Proteins (38) Interactants (200) Wiki
Gene Symbol: il6st

Gene Name: interleukin 6 signal transducer

Synonyms: xgp130 , gp130 ( Add synonyms , Nomenclature history )

Gene Function: signal transduction

Protein Function :

Interactants: Loading ...
Diseases:  External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
Xenbase Gene ID XB-GENE-855663 XB-GENE-17341582 XB-GENE-866605
Gene Symbol il6st il6st.L il6st.S
Chromosome Chr01 chr1L Scaffold33
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100489642
mRNA NCBI Nucleotide RefSeq RefSeq
Protein NCBI Protein TrEMBL TrEMBL RefSeq TrEMBL RefSeq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine il6st il6st.L il6st.S
MOD Entrez Gene Genetic Phenotypes Gene Expression
OMIM:Gene, HGNC, GeneCards IL6ST OMIM Ensembl, Protein Atlas, Allen Brain Atlas
MGI, AGR Il6st MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
il6st ZFIN Ensembl
fruit fly
First Peripheral nervous system defects in erbB2 mutants following genetic rescue of heart development., Genes Dev 1999  
Most Recent Conservation and divergence of protein pathways in the vertebrate heart., PLoS Biol 2019                                                      
All View All Papers 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 16 terms 2 terms 2 terms
KEGG Pathways K05060 K05060
KOG [T] Protein tyrosine phosphatase (alt_id KOG:4228)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks il6st
Clones Horizon Horizon Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.13.1
Major funding for Xenbase is provided by grant P41 HD064556