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Summary Expression Gene Literature (365) Nucleotides (32) Proteins (15) Interactants (526) Wiki
XB-GENEPAGE-483208

Gene Symbol: nodal

Gene Name: nodal growth differentiation factor

Synonyms: Xnr-4, Xnr4, nr4, nodal4, Nodal homolog 4 Add Xenopus synonyms

Gene Function: transforming growth factor beta and bone morphogenetic protein related protein

Interactants: tgfb1(93) , t(75) , nodal1(68) , cer1(58) , gsc(57) , chrd(50) , smad2(49) View All

Disease Associations:
 
  XB-GENE-483209 XB-GENE-864954
Molecules tropicalis laevis
Gene JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1 JGI XL Genome 6.0
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein Refseq UniProtKB
Genomic tropicalis laevis
Genome Browser
GBrowse
tropicalis genome v7.1 gene model

GBrowse
laevis genome v6.0 gene model

Links
tropicalis 4.1 synteny Metazome
Expression tropicalis laevis
UniGene Xl.378
Unigene EST Profile EST Profile
GEO data GEO
Images 2 expression image(s) for tropicalis and laevis
Phenotype tropicalis laevis
Smith Morpholino Screen tgas097d22      
Orthology
MOD Entrez Gene Genetic Phenotypes Morphants
human
OMIM:Gene, HGNC NODAL OMIM:601265
mouse
MGI Nodal All
zebrafish (a-gene b-gene)
ZFIN ndr2 All
Publications
First: Effects of ionic concentration on permeability properties of nodal membrane in myelinated nerve fibres of Xenopus laevis. Potential clamp experiments. [Acta Physiol Scand 1973]
Most recent: Commitment to nutritional endoderm in Eleutherodactylus coqui involves altered nodal signaling and global transcriptional repression. [J Exp Zool B Mol Dev Evol 2014]
View All Papers 68 paper(s) referencing morpholinos
Functional Ontologies
GO: Molecular: growth factor activity
      Biological: growth
      Cellular Component: extracellular region
EC:
KOG: [T] Transforming growth factor beta, bone morphogenetic protein and related proteins
Reagents tropicalis laevis
CRISPR / TALEN Design CRISPR / TALEN Design CRISPR / TALEN
Clones EXRC - 1 clone(s) EXRC - 1 clone(s)  
Thermo Scientific
geneservice/RZPD imagenes
Affymetrix 1.0 StrEns.4645.1.S1_at Xl.378.1.S1_at
Affymetrix 2.0 Xl2.378.1.S1_at

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