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Summary Expression Gene Literature (255) Nucleotides (513) Proteins (31) Interactants (834) Wiki
XB-GENEPAGE-484552

Gene Symbol: sox2

Gene Name: SRY (sex determining region Y)-box 2

Synonyms: XLSOX-2, Sox-2, XSox2, Xsox-2, anop3, mcops3 Add Xenopus synonyms

Gene Function: HMG-box transcription factor

Interactants: chrd(77) , snai2(72) , t(67) , otx2(65) , tubb2b(61) , nog(55) , bmp4(52) View All

Disease Associations: Microphthalmia, syndromic 3; Optic nerve hypoplasia and abno...
1/5
 
  XB-GENE-484553 XB-GENE-865099
Molecules tropicalis laevis
Gene JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1 JGI XL Genome 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq UniProtKB Refseq UniProtKB
Genomic tropicalis laevis
Genome Browser
GBrowse
tropicalis genome v7.1 gene model

GBrowse
laevis genome v6.0 gene model

Links
tropicalis 4.1 synteny Metazome
Expression tropicalis laevis
UniGene Str.6201 [+] Xl.188
Unigene EST Profile EST Profile EST Profile
GEO data GEO
Images 301 expression image(s) for tropicalis and laevis
Orthology
MOD Entrez Gene Genetic Phenotypes Morphants
human
OMIM:Gene, HGNC SOX2 OMIM:206900
mouse
MGI Sox2 All
zebrafish (a-gene b-gene)
ZFIN sox2
chicken
GEISHA SOX2
Publications
First: Preventing the loss of competence for neural induction: HGF/SF, L5 and Sox-2. [Development 1997]
Most recent: NEDD4L regulates convergent extension movements in Xenopus embryos via Disheveled-mediated non-canonical Wnt signaling. [Dev Biol 2014]
View All Papers 107 paper(s) referencing morpholinos
Functional Ontologies
GO: Molecular: DNA binding
      Biological: regulation of transcription, DNA-dependent
      Cellular Component:
EC:
KOG: [K] HMG-box transcription factor
Reagents tropicalis laevis
CRISPR / TALEN Design CRISPR / TALEN
Design CRISPR / TALEN
Clones EXRC - 2 clone(s) EXRC - 1 clone(s)  
Thermo Scientific Thermo Scientific
geneservice/RZPD imagenes geneservice/RZPD imagenes
Antibody Sox2 Ab1, Sox2 Ab2, Sox2 Ab3 Sox2 Ab1, Sox2 Ab3
Affymetrix 1.0 Str.43967.1.A1_at [+] Xl.188.1.S1_at [+]
Affymetrix 2.0 Xl2.188.1.S1_a_at [+]

Symbol legend[+]

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