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Summary Expression Gene Literature (299) Nucleotides (515) Proteins (32) Interactants (996) Wiki
XB-GENEPAGE-484552

Gene Symbol: sox2

Gene Name: SRY (sex determining region Y)-box 2

Synonyms: XLSOX-2, Sox-2, XSox2, Xsox-2, anop3, mcops3 Add Xenopus synonyms

Gene Function: HMG-box transcription factor

Interactants: chrd(87) , snai2(82) , t(82) , otx2(75) , tubb2b(74) , nog(67) , bmp4(65) View All

Disease Associations: MICROPHTHALMIA, SYNDROMIC 3; MCOPS3
1/5
 
Xenbase Gene ID XB-GENE-484553 XB-GENE-865099
Current JGI Annotation sox2
Molecules tropicalis laevis
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq UniProtKB Refseq UniProtKB
Genomic tropicalis laevis
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v6.0 gene model
Links
tropicalis 4.1 synteny Metazome
Expression tropicalis laevis
UniGene Str.6201 [+] Xl.188
Unigene EST Profile EST Profile EST Profile
GEO data GEO
Images 319 expression image(s) for tropicalis and laevis
Phenotype tropicalis laevis
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Morphants
human
OMIM:Gene, HGNC SOX2 OMIM:206900
mouse
MGI Sox2 All available mutants
zebrafish
ZFIN sox2
chicken
GEISHA SOX2
Publications
First: Neural crest formation in Xenopus laevis: mechanisms of Xslug induction. [Dev Biol 1996]
Most recent: Kcnip1 a Ca(2+-)dependent transcriptional repressor regulates the size of the neural plate in Xenopus. [Biochim Biophys Acta 2015]
View All Papers 123 paper(s) referencing morpholinos
Functional Ontologies
GO: Molecular: DNA binding
      Biological: regulation of transcription, DNA-dependent
      Cellular Component:
EC:
KOG: [K] HMG-box transcription factor
Reagents tropicalis laevis
CRISPR / TALEN CRISPR tools CRISPR tools
Clones EXRC - 2 clone(s) EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
Antibody Sox2 Ab1, Sox2 Ab2, Sox2 Ab3 Sox2 Ab1, Sox2 Ab3
Morpholino sox2 MO1, sox2 MO2, sox2 MO3, sox2 MO4, sox2 MO5 sox2 MO1, sox2 MO2, sox2 MO3, sox2 MO4, sox2 MO5
Affymetrix 1.0 Str.43967.1.A1_at [+] Xl.188.1.S1_at [+]
Affymetrix 2.0 Xl2.188.1.S1_a_at [+]

Symbol legend[+]

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