hsp90ab1 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (3)

Nucleotides (2369)

Interactants (10)

XB-GENEPAGE-495310

Gene Symbol: hsp90ab1 Gene Name: heat shock protein 90kDa alpha (cytosolic), class B member 1 Synonyms: hsp90beta, hsp90b, hsp90 beta Add Xenopus synonyms Gene Function: Endoplasmic reticulum glucose-regulated protein (GRP94/endoplasmin), HSP90 family Interactants: hsp90aa1.1(3) , hsp70(2) , araf(1) , cdc37(1) , hsf1(1) , map2k1(1) , mapk1(1) View All

XB-GENE-495311

XB-GENE-866421

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001030484\|Xenopus (Silurana) tropicalis heat shock protein 90kDa alpha (cytosolic), class B member 1 (hsp90ab1), mRNA CAATTCCCCAGCAGTGTTCGGCCGCGGAGATCCTTAAGCAGCCAAGATGCCTGAAGTCGCTCACAATGGAGAGGAGGAGGTGGAGACATTTGCCTTCCAGGCGGAGATTGCGCAGCTCATGTCCCTCATCATCAACACCTTCTACTCCAACAAAGAAATCTTCCTGCGAGAGTTGATCTCCAACGCCTCCGACGCCCTGGATAAGATCCGATACGAGAGTCTGACCGATCCCTCCAAGCTGGACAGCGGCAAAGACCTGAAGATCGACATCATTCCCAACCGCCAGGAGCGCACACTGACTGTCATCGACACCGGGATTGGCATGACCAAGGCCGACCTCATCAACAACCTGGGAACCATCGCCAAGTCCGGCACCAAGGCTTTCATGGAGGCCCTGCAGGCTGGTGCTGACATCTCTATGATTGGTCAGTTCGGTGTGGGTTTCTATTCTGCGTACTTGGTGGCAGAGAAGGTCTTGGTCATCACCAAACACAACGATGATGAACAGTACGCGTGGGAATCCTCCGCCGGCGGCTCTTTCACCGTGAAGACTGACCATGGTGAGCCCATTGGCCGTGGTACCAAAGTCATCCTCTACCTGAAGGAAGATCAGACCGAGTACCTGGAGGAGAAACGTGTCAAGGAAACCGTGAAGAAACACTCGCAGTTCATTGGCTACCCAATCACCCTCTATCTGGAGAAGGAGAGGGAAAAGGAGATCAGCGACGATGAGGCAGAGGAGGAGAAAGAGGAAGAAAAGAAGGAAGAGGAGGGAGAGAATGACAAACCTAAAATAGAGGACGTGGGCTCCGATGAGGAAGAGGAGGGGAAGGACAAGAAGAAAAAGACTAAGAAGATCAAGGAGAAGTACATCGACCAGGAGGAGCTGAACAAAACCAAGCCCATCTGGACCCGTAACCCCGACGACATCACCCAGGAAGAGTACGGAGAGTTCTACAAGAGCCTGACCAATGACTGGGAGGATCACTTGGCTGTGAAGCACTTCTCTGTGGAGGGGCAACTGGAGTTCCGCGCTCTGCTCTTCATTCCCCGCCGCGCCCCCTTTGATCTGTTTGAGAACAAGAAGAAGAAGAACAACATCAAGCTGTACGTGCGCCGCGTCTTCATCATGGATAGCTGCGACGAGCTGATCCCAGAGTATCTGAACTTCATCCGCGGGGTGGTGGATTCTGAGGATCTGCCCTTGAACATTTCCCGTGAAATGCTGCAGCAGAGCAAGATCCTGAAGGTGATCCGCAAGAACATTGTCAAGAAGTGCCTGGAGCTCTTCACCGAGCTGGCCGAGGACAAGGAGAACTACAAGAAGTTTTACGAGGCTTTCTCCAAGAACCTGAAGCTCGGCATCCACGAGGATTCTACCAACCGCAAGAAGCTGTCTGAGCTCCTCAGGTACCACACTTCCCAGACAGGCGACGAGATGGCCTCCCTAACAGAGTATGTGTCCCGTATGAAGGAGAACCAGAAAAGCATCTACTACATAACTGGTGAGAGCAAGGACCAGGTGGCCAACTCCGCCTTCGTGGAGCGGGTGAGGAAGCGTGGCTTCGAGGTGGTCTACATGACTGAGCCCATCGACGAGTACTGCGTGCAGCAGCTGAAGGAGTTCGACGGGAAGACGCTGGTGTCTGTGACCAAGGAGGGCCTGGAGCTGCCAGAGGACGAGGAAGAGAAGAAGATGATGGAAGAGAACAAGACCAAATTTGAGAGTTTGTGCAAACTGATGAAGGAAATTCTGGACAAGAAAGTAGAGAAGGTCACCGTGTCCAACAGACTCGTCTCCTCTCCCTGCTGTATCGTCACCAGCACCTACGGCTGGACCGCCAACATGGAGCGCATCATGAAAGCGCAAGCTCTGCGGGACAATTCCACCATGGGCTACATGATGGCTAAGAAGCACTTGGAGATCAACCCCGAGCACCCCATCGTGGAGACCCTGAGGCAGAAAGCGGAAACCGACAAGAACGACAAAGCAGTGAAGGACCTGGTGGTGCTGCTCTTCGAGACCGCGCTGCTGTCATCCGGCTTCTCCCTGGACGACCCCCAGACGCACTCAAACAGGATCTACAGGATGATCAAGCTGGGTCTGGGTATTGATGATGACGATGCAACGGTGGAGGAAACTTCCCCCTCGGTGGCAGACGAGATCCCACCCCTAGAGGGCGACGAAGATGCTTCTCGCATGGAGGAAGTCGACTAATCGGTTTGCTGCCCGCTCGTCCTGCCCCCTCCCACCCGCGTATGTGCACTGTCTGTAACTCGGTAGGGGGGCGACTTCTCCCTTGGACTCTAAATATCACATGATACTGGGGATGGACTTCCCTCCTTATAGAATATATTTGGGGGAGCTTCAAGACTGATGGCTGCTGACTTTAACCCTTTCCTCTGCACCCCCCTTGTTGTGTTCCAGTCTGAGCAGTTAGTTATGTAAGTTATTGTAGCAGTATGGCAGCTAGCTTGGCTTGAGGTAGCCCTGAGTTAGTGGCCCGCTGTTAGCCAGCTGCTGGGGGGGGGTCTGTTTGACTCTCTCAATGCACCTTACAGGCCCCCCCTCTAATCCTACCCTCTGCCACTATTGTAATGGGCGTGTCCCTCTGTGCCCCCCCTGAGGCACGGGGGGTACTTACTGGGAAGCTTTAGAGACCCCCCTGCTGCCTTCTCCCATTCACTTGCATGGGGGGGGCGATTGAATGTGCTGGTGTTTGCAAATAGAAACGCCAGGCCAGTCTGGGGGGGTGAGGTACTTCTGCCCAATGCTACCTCCATCTGTAGCACCCCCAAATCTGCTGAGTGGTAGCCCCCATCTCTCTGACTGGAATCTCGTGCCCCCGCCCCCAGGATGTCTTGAATGCTGAGACCCCACCCCCATCCTACACATCTCTCTATCGAGAGCCTCAATACGGAACTTTATTTTATTTTTTGTTGTTGTAAAGTTGAGAAATGTTGCGCAAAATAAAGATCTTTTTACAGTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001093155\|Xenopus laevis heat shock protein 90kDa alpha (cytosolic), class B member 1 (hsp90ab1), mRNA CCAATTCCCCAGTAGTCACCGGGAGCGGAGATCCACTAGCAGACAAGATGCCAGAAGTTGCCCACAATGGCGAGGAGGAGGTGGAGACATTTGCCTTCCAGGCGGAAATTGCGCAGTTGATGTCCCTGATCATCAATACCTTCTACTCCAACAAAGAGATCTTTCTGCGAGAATTAATCTCCAACGCCTCAGATGCCCTGGATAAGATCCGATATGAGAGCCTGACTGACCCATCTAAGCTGGACAGTGGCAAGGACCTGAAGATCGACATCATTCCTAACCGGTTGGAGCGCACACTGACTATGATTGATACCGGAATTGGCATGACCAAAGCTGACCTCATCAACAATCTGGGAACCATTGCCAAGTCCGGCACCAAGGCTTTCATGGAGGCACTACAGGCTGGTGCTGACATCTCCATGATTGGTCAGTTCGGTGTGGGTTTCTATTCTGCATACCTGGTGGCAGAGAAGGTTGTGGTCATTACCAAACACAATGATGATGAGCAATATGCTTGGGAATCTTCTGCTGGTGGCTCCTTCACTGTGAAGGTTGATACTGGTGAGCCCATTGGCCGTGGTACCAAAGTCATCCTGCATCTGAAGGAAGATCAGACTGAGTACCTGGAAGAGAAACGTGTCAAGGAAACTGTAAAGAAGCATTCCCAGTTCATTGGCTACCCTATCACCCTTTATCTGGAAAAGGAGCGGGAAAAGGAGATCAGTGATGATGAGGCAGAGGAGGAGAAAGAAGAAAAGAAGGAAGAGGAAGGAGAGAACGACAAACCTAAAATAGAGGATGTGGGCTCTGATGAGGAAGAGGAAGGGAAAGATAAGAAGAAAAAGACCAAGAAGATCAAGGAAAAGTACATTGATCAGGAGGAGCTGAACAAAACCAAGCCCATCTGGACCCGCAACCCTGATGATATTACACAGGAAGAGTATGGAGAGTTCTACAAGAGTCTGACCAATGACTGGGAGGATCACCTGGCTGTAAAGCATTTCTCTGTGGAAGGGCAGCTGGAGTTCCGTGCTCTGCTATTCATCCCCCGCCGTGCTCCCTTTGACCTTTTTGAGAACAAGAAGAAAAAGAACAACATCAAACTGTATGTGCGCCGTGTGTTCATCATGGATAGCTGCGATGAGCTGATCCCAGAGTATCTGAACTTTGTCCGTGGGGTGGTCGATTCTGAGGATCTGCCCTTGAACATTTCCCGTGAGATGCTCCAGCAGAGCAAGATTCTGAAGGTGATCCGCAAGAACATTGTCAAGAAGTGTCTGGAGCTCTTCTGTGAGCTGGCTGAGGACAAGGAGAACTACAAGAAATTCTACGAGGGTTTCTCAAAGAACCTGAAGCTTGGTATCCATGAGGACTCCACAAACCGCAAGAAGCTGTCTGAGCTCCTGAGGTACCACACTTCCCAGACAGGTGATGAGATGGCCTCTCTAACAGAGTATGTGTCCCGGATGAAGGAGAACCAGAAGAGCATCTATTACATAACCGGTGAGAGCAAGGACCAGGTTGCAAACTCTGCCTTTGTGGAGCGAGTAAGGAAGCGCGGCTTCGAGGTGGTGTATATGACTGAGCCAATCGATGAGTACTGTGTGCAGCAGCTGAAGGAGTTTGACGGGAAGACTCTAGTGTCTGTGACCAAGGAGGGCCTTGAGCTTCCTGAAGATGAGGAGGAAAAGAAGACCATGGAGGAGAACAAGACTAAATTTGAGAGTTTGTGCAAACTGATGAAGGAAATCTTGGACAAGAAAGTTGAGAAGGTCACCGTGTCCAACAGACTCGTCTCATCTCCTTGCTGCATTGTGACCAGCACCTACGGCTGGACCGCAAATATGGAACGCATCATGAAAGCTCAAGCTCTTCGGGACAATTCCACAATGGGCTACATGATGGCTAAGAAGCACTTGGAAATCAACCCCGAGCACCCCATTGTGGAGACACTGAGGCAGAAGGCAGACACTGACAAAAATGACAAAGCCGTGAAGGACCTAGTGGTGCTGCTCTTTGAGACTGCGCTGCTGTCGTCTGGCTTCTCACTGGATGATCCCCAGACACACTCAAACAGAATCTACAGGATGATCAAGCTCGGTCTGGGTATTGATGACGATGATGCACCTATAGAAGAAGCGTCACCCTCTGTGCCAGATGACATCCCACCTCTGGAGGGTGAAGAAGACGCTTCTCGCATGGAGGAAGTCGATTAATCCGTTTGCTGTAATTAATACCTGTCCTGCCCCCTCCCACCTGCATATGTGCACTGTCTGTAAACTCAGTAGGGGGACGACTTCTCCCTTGGACTTTAAATGTCACGTGATACTGGGGATGGATTTCCTTCCTTATAAAATATATTTGGGGAAGCTTCAAGACGATGGCTGCTGTATCCTTTCTCTGCACCCCATTTTTGTGTTCCAGTCTCTGAGCAGTTTAGTTCTGTAAGTTATTGTAGCAGTATGGCAGCTAGCTTGGCTTGTGATAGCCCTGTGTTAGTGGCCAGTTGGTTACTGAGCTACCGGTGGGTCTGTTAGAATCTGTAAACACATGATCTTACAGGCTTGCCTCTAATCCTACCCTGTGCTGCTACAGTAATGGGCATGGTGGATTAATATGTTCTAATATGGTGCAGGGCCACTTACCTGGCTGAGAAGCTTTAGTAATCATCCTGCTGCCCCTCTCATTCACTTGCATGGGGAATGACTAATGTGCTGCTGACTGTCAGGCCTTGTGCTACCTGCCATTTTCATTCAGTCAGTGGGAGGAAACCTGGTGCTTGTCAGCCAATGCTGCCTACATCTGTAGCACCGCAGTGTCACCCCCCTCCCCCCCAAATCTGACCTGTGTCGAGTGTTAGCCCCTCTCAGACTGGAATCTCTTGCCCCTCCCCAGATGTCTTGAATGCTCTATCACCCCAGTCCTACACCTCTCTATAGAGAGCCTCAATACGGAAACTTTATTTTATTTTTTGTTGTAAAGTTAAAAATGTTGCGCAAAATAAAGATCTTTTTACAGTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001025655\|heat shock protein 90kDa alpha (cytosolic), class B member 1 [Xenopus (Silurana) tropicalis] MPEVAHNGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKDLKIDIIPNRQERTLTVIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVLVITKHNDDEQYAWESSAGGSFTVKTDHGEPIGRGTKVILYLKEDQTEYLEEKRVKETVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKEEEKKEEEGENDKPKIEDVGSDEEEEGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFTELAEDKENYKKFYEAFSKNLKLGIHEDSTNRKKLSELLRYHTSQTGDEMASLTEYVSRMKENQKSIYYITGESKDQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEEEKKMMEENKTKFESLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPEHPIVETLRQKAETDKNDKAVKDLVVLLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDDDDATVEETSPSVADEIPPLEGDEDASRMEEVD	Refseq >NP_001086624\|heat shock protein 90kDa alpha (cytosolic), class B member 1 [Xenopus laevis] MPEVAHNGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKDLKIDIIPNRLERTLTMIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVKVDTGEPIGRGTKVILHLKEDQTEYLEEKRVKETVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKEEKKEEEGENDKPKIEDVGSDEEEEGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFVRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFCELAEDKENYKKFYEGFSKNLKLGIHEDSTNRKKLSELLRYHTSQTGDEMASLTEYVSRMKENQKSIYYITGESKDQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEEEKKTMEENKTKFESLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPEHPIVETLRQKADTDKNDKAVKDLVVLLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDDDDAPIEEASPSVPDDIPPLEGEEDASRMEEVD

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.34175 [+] Str.63738	Xl.29353
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	HSP90AB1
mouse		MGI	Hsp90ab1	All(4) Gene Trapped(1) Targeted, other(2) Targeted, knock Out(1)
zebrafish		ZFIN	hsp90ab1	2 Lines(s)

Publications
First:		Evaluation of stress-inducible hsp90 gene expression as a potential molecular biomarker in Xenopus laevis. [Cell Stress Chaperones 1996]
Most recent:		Expression of hsp90 alpha and hsp90 beta during Xenopus laevis embryonic development. [Iran Biomed J 2010]
		View All Papers

Functional Ontologies
GO: Molecular:		ATP binding unfolded protein binding
Biological:		protein folding
Cellular Component:
EC:
KOG:		[O] Endoplasmic reticulum glucose-regulated protein (GRP94/endoplasmin), HSP90 family

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.6671.1.S2_x_at [+] Str.34175.1.A1_at Str.6671.2.A1_a_at Str.43692.1.A1_at Str.6671.1.S1_at Str.6671.4.A1_a_at	Xl.26082.1.S1_at
Affymetrix 2.0			Xl2.26082.3.S1_a_at [+] Xl2.29353.3.S1_a_at Xl2.29353.1.S1_x_at Xl2.29353.2.S1_at

Symbol legend[+]