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Summary Expression Gene Literature (24) GO Terms (11) Nucleotides (633) Proteins (38) Interactants (537) Wiki
XB-GENEPAGE-919630
Gene Symbol:
skp1

Gene Name:
S-phase kinase-associated protein 1

Synonyms:
skp1a ( Add synonyms , Nomenclature history )

Gene Function:
ubiquitin ligase component

Protein Function :
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcriptio...[+]



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-919631 XB-GENE-919643 XB-GENE-17344373
Gene Symbol skp1 skp1.L skp1.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 549273
380538
108712619
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq RefSeq Swiss-Prot NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine skp1 skp1.L skp1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SKP1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Skp1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Skp1 Ensembl
zebrafish
ZFIN, AGR skp1 ZFIN Ensembl
chicken
GEISHA SKP1 Ensembl
fruit fly
worm
Publications
First The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin., Oncogene 1999  
Most Recent Claspin - checkpoint adaptor and DNA replication factor., FEBS J 2019  
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 9 terms 4 terms 0 term
PANTHER skp1
KEGG Pathways K03094 K03094
KOG [O] SCF ubiquitin ligase, Skp1 component
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks skp1
ORFs skp1 ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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