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Summary Expression Gene Literature (9) GO Terms (10) Nucleotides (190) Proteins (42) Interactants (243) Wiki
XB-GENEPAGE-922820
Gene Symbol:
dad1

Gene Name:
defender against cell death 1

Synonyms:
DAD-1 ( Add synonyms , Nomenclature history )

Gene Function:
negative regulator of programmed cell death

Protein Function :
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an...[+]


InterPro :
DAD/Ost2

Interactants:
Loading ...

Diseases: 


External Links:
1/2
 
Xenbase Gene ID XB-GENE-922821 XB-GENE-17344095 XB-GENE-922833
Gene Symbol dad1 dad1.L dad1.S
Chromosome Chr1 chr1L Scaffold131
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549694
108714902
397721
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein TrEMBL RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine dad1 dad1.L dad1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards DAD1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Dad1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Dad1 Ensembl
zebrafish
ZFIN, AGR dad1 ZFIN Ensembl
chicken
GEISHA DAD1 Ensembl
fruit fly
FLYBASE Dad1 Ensembl
worm
Publications
First Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells., Mol Cell Biol 1993  
Most Recent Asymmetric distribution of biomolecules of maternal origin in the Xenopus laevis egg and their impact on the developmental plan., Sci Rep 2018                  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 9 terms 4 terms 5 terms
PANTHER dad1
KEGG Pathways K12668 K12668 K12668
KOG [DO] Defender against cell death protein/oligosaccharyltransferase, epsilon subunit
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks dad1
ORFs dad1 ORF1 dad1.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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