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Summary Expression Gene Literature (2) Nucleotides (104) Proteins (20) Interactants (5) Wiki
XB-GENEPAGE- 922911

Gene Symbol: kmt2a

Gene Name: lysine (K)-specific methyltransferase 2A

Synonyms: mll1 , hrx , trx1 , all-1 , cxxc7 , htrx1 , knt2a , mll1a , mll/gas7 , tet1-mll
Add Xenopus synonyms , Nomenclature history


Gene Function: zinc finger transcription factor

Interactants: dot1l (1) , hist2h2ab (1) , hist2h2be (1) , hoxc8 (1) , kmt2b (1) , wdr5 (1) , View All

OMIM Disease Associations: HAIRY ELBOWS, SHORT STATURE, FACIAL DYSMORPHISM, AND DEVELOP...
 
Xenbase Gene ID XB-GENE-922912 XB-GENE-6256014 XB-GENE-17331414
Gene Symbol kmt2a kmt2a.L kmt2a.S
Chromosome: scaffold_7 chr7L Scaffold80
Molecules tropicalis laevis .L laevis.S
Gene GBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 GBrowse 7.2 GBrowse 6.0 GBrowse 9.1
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein
Genomic tropicalis laevis .L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis .L laevis.S
Ensembl Ensembl
UniGene Str.39536 Xl.34942 [+]
RNA-seq profile: Owens, Blitz et al. 2016 kmt2a
Images 0 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis .L laevis.S
XenMine kmt2a kmt2a.L kmt2a.S
Phenotype tropicalis laevis .L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards KMT2A OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Kmt2a MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
kmt2a ZFIN Ensembl
chicken
GEISHA KMT2A Ensembl
fruit fly
worm
WORMBASE
Publications
First: WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. [Cell 2005]
Most recent: One-pot refolding of core histones from bacterial inclusion bodies allows rapid reconstitution of histone octamer. [Protein Expr Purif 2015]
View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies
GO: Molecular: DNA binding   calcium ion binding   glucan 1,4-alpha-glucosidase activity   More[+]
      Biological: DNA recombination   DNA repair   regulation of transcription, DNA-templated  
      Cellular Component: nucleus  
EC: glucan 1,4-a-glucosidase
PANTHER: kmt2a
KOG: [K] Transcription factor TCF20
Reagents tropicalis laevis .L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
Affymetrix 1.0 Str.42957.1.A1_s_at [+]
Affymetrix 2.0 Xl2.48143.1.S1_at [+]

Symbol legend[+]

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