kmt2a Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (1)

Nucleotides (106)

Interactants (3)

XB-GENEPAGE-922911

Gene Symbol: kmt2a Gene Name: lysine (K)-specific methyltransferase 2A Synonyms: mll1, hrx, trx1, all-1, cxxc7, htrx1, knt2a, mll1a, mll/gas7, tet1-mll Add Xenopus synonyms Gene Function: zinc finger transcription factor Interactants: hoxc8(1) , kmt2b(1) , wdr5(1) , View All

XB-GENE-922912

XB-GENE-6256014

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >BC155710\|Xenopus tropicalis myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog), mRNA (cDNA clone IMAGE:7642164), partial cds CAAAATGGCGCACAGCTGTCGGTGGCGGTTCCCTGCTCGGCCCGGGACTGGCCGGAGGCTGGGGGCCCGGCACCGATTATCAGCTATACTGATAGACGATGTGAGCGAGTACAGAAGCAACCCTGGCGCCTCTGGGAGCGCTGGCGCAAGCTCTGCGGGCACATTGGCCCCCGGGGGCCCTGGGAACTGTTTGGGGGTTGCACTCGGGTTTGATGCAGCGCTGCAGGTGTCGGCGGCAATTGGAAACAACCTGAGAAGATTTAGGGACGTGTCCGGAGGAAGCAGCGGAGAGGAGGAGCAGTTTCTAGGATTTGGCTCAGATGAGGAAGTTAAAGGTCGCAGCCCTGCAAAATCACCCAAAGACCAGACAACACAAAGAAAACCTCGCGGTAGACCCCGCAACAGTCTGTCCCGGTGTTCTGATGCGTCATCCAATCTTTGTGAAAACACCACATCAACCCTAAATAAACAGGAGACCAGACTCTTAGATAAAGTAAAGAAGCCTGAGAGTAAAACAGAAGAGAAAAAACGGGGAAGACCCCCAGCACATGGCAATGTTAAGTTTAAACTGCCACAGGAGAAAAGGGATGGCACTGAATCCATCAAAGCTCCCTGTGAAGAAAAATCAAAAAGGAGAAAACCATCTGCCACATTCCAGCATGCTGCCAAAATCAAGAAGCTCAGAGCAGGCAAACTATCTCCTTTAAAGTCAAAGTTTAAGAGCAATAAATTAAAGTTAGGTAGAAAAGGAGGGGTCTCTATTGTCCGAAGGCGTGGAAGACCACCATCTTCTGAAAGGTTCAAGACAGACACTCATGGTTCATTTCCAAAGCAGGTTCCCACAGATCGAAGTCAACGGGGTAATAAGGATGTGTCGCCACAACCTTCAAAAGAAGATACCAGAGTGTCAGTAAGGCAGAGCCCACGTAGAATGAAGCCTGTGAGGATTATTCCTTCCTCCAAGAGGACAGACACTGCCATTGCCAAGCAACTTTTGCAGAAGGCCAAAAAAGGGGCTCAGAAAAAAATGGAGTTGGAAGCAGCAAAACTTCAAGGCCGCAAGGGTGGGACGCAGTTAAAGAATATACGTCAGTTCATTATGCCTGTAGTTAGCACAGTCTCATCCCGTATCATCAAGACACCAAGAAGGTTTATTGAAGATGAGGACTATGAACCTCCAATAAAGATAGCTCGTTTAGAATCAGCCCCCAACGGTAGTCGATTTAGCACTGCCTCATGTGGATCCAGTGAGAAGTCAAGTGCTGCATCTCAGCAGTCTTCACAAGCCACCTCAGATGACTCTCGCTCTAGCAGTCCTAGTGTCGACACCTCAACAGAGTCTCAAGCCTCAGAGGAGACACCAGTTGTGTCTGAGCCACAGGGACGAGTTGCTGAGACCATTACATCAGTCCCAACCCAACAACAGCCCCTAGAAAGTAATGGTGTAAGGACCCGAAGGTTACCTGTCTGCAATAAGAACTTTAGTTCAAGGCCGGCTAAGAAGATAGTTTTACGTCCATCTTTTCAGCAAAAGTCCTCTGTGTCTCCACCTCCCCCACTTCTAAGTCCACCCACACCTCTACAGCCTTCTGCCAGCCTCCCTGATCACACACCTTGGTTGATGCCCGCTATTCCTATGGCAACACCTTTTATCTCTGCCTCACGCATGCACGAGAAACGAAGGTCTATATTACGGGAACCAACTTTCCGCTGGACTTCCCTTAAACATTCCAGATTAGAGTCTCAGTACTTTTCTTCTGCTAAATATGCCAAAGAAGGACTCATAAGGAAACCAATCTTTGACAATTTTAGACCACCTCCTCTAACTCCAGAAGATGTAGGATTAGCTACTGCATCAGGATTCCCTTCACATACTGTTGTGGGGCCCGGAAGACTCTTTTCACATATCCATTCTTCAGGTGCTAGGTTTGATGTGCACAAAAGAAGCCCTCTTCTTCGTGCACCCAGGTTCACTCCTAGTGAAGCACATTCTCGCATATTTGAATCAGTCACCCTTCCACCTTCTGCTGGTCGTGCCAGCGGGACATCTTCCATGATGGGCATTTCTCGGAGAAGTAAAAGGAGGGTTTTTAATCCCATCCGCAGCTCTGAGCCTAAATCACCATCTCACTCCATGAGGACACGGAGCAGGAGAGTAGGCAACAGCAGTTTGTCTGTGCTTGCTTCACCTCCATCCAGTTCACTTACAGACATTTCAGTAAGTCCCCTTGCCACCAGTGCCTTAAACCCTAGTTTCCCTTTCTCCTCCTCTTCAGTTACTCCAGCATCTGTAGATATTGCAGAGAAAATTCAGAAACCGCGAAAACCAACCAGCACTCCTGCAGAACACTTTACTTCTTCACCCAGCAGCTCTCCAGCCCTCTTCCCATGGTTCCCTTCAAGTGTACAGATGGAGAAAGGAAAAAGTAAAAATAGGGGATCAGTGGAATCTTCCAAAGAAAGGGAAGTTGAGAAAAACAGGGAGAAAGACCGTGAAAAAGAAAATTCCCGTGATTCCAGGAGGGATAAACGAAAAAAGAGCTCAGACTCTGGGTGTAAAATAAGCAGGGAGAGAAATGATGAAGAAGGAATCGTGACTGCCACTCAGATTAAAATGTCAGTGAGAAAGAAGCCTGTCACAGTGGAATCTAATGTAGATATTTCTCCAGCCTCAATCCATACAGATCAGATACCTGCCAAAAACAAAATATCAAAAAAAGGCAGGCCAGTATCTGAAAAGACCGAGCTGGATACCTGTGCCAAATCTCCTACAGCAGAGACTCAAGCACAGCTCCCAGCCCAACCTGTCAGTGCCCTAAAGCATCCCTCTACATCTATTAGCTCTATGCTGGCTCAAGCAGACAAGTTTCCTGTCTCTGACAAACATGTGGCTACTCTTCTGAGAAAGGCAAAAGCCCAGCTGTGTAAGATTGAGAAGAGCAAGTTTCTGAAACAAACAGACCAGCCCAAGGCTCAGGGCCAAGAAAGTGACTCCTCAGAGGCATCTGTTCGTGGTCCAAGGATAAAACATGTTTGTCGTCGAGCTGCTGTAGCCTTGGGGCGCAAAAGGGCAGTTTTTCCAGATGACATGCCGACATTGAGTGCCTTACCTTGGGAGGAAAGAGAGAAGGTCCTGTCTTCCATGGGAAATGATGACAAGTCCTCCATTGCTGGATCAGAGGATGCTGATCAGCCAGCTCCACCTCTCAAACCCATCAAACAAATCACACGCAACAAGGCACAGCAAGAGCCTCCTGTGAAAAAGGGGCGCAGATCACGGCGCTGTGGACAGTGTCCAGGCTGCCAGGTTCCTGATGACTGTGGCATATGTACTAACTGTCTTGATAAACCTAAATTTGGTGGACGCAACATAAAAAAACAGTGTTGCAAGATGCGGAAATGCCAGAACTTGCAGTGGATGCCATCTAAGGCTTATCTTCAGAAGCAGGCTAAAGCTGCAAAGAAGAAAGAAAGAAAATGCAAGGTGACTGAAAAGAAAGAATTGCCACCTGTTAAGAGCCCTTCGGAACTCATTGTAAAACCTGTCTCAGCACCTGGCACCAGCTCTCCCCCTGTGCAAGAAGAACCTGCAACCCCATCTCTGCCTCAAAAAAAGAATGAACCTCCCAAGAAACAGACTGAGGAAAAATCAGAAGAACAAATTCCTGCTGCTTCCACAAGTGAAACCAAGCAATCTCCTAATTCCCGTAAAACCACCAAGCAGCCTCCTTCACAGCCTTCCACTACCATTGCAATGACCCCATTAACTGCCACACCATCTACAAAGAAAGAGGCTCCTAAGCCAATTCCTCCAGAATCGAGGAAAAAGCAGCCACCAGTGCTCCCAGACAATACCTCAACTGAACAGAACAAACAGAAAAAGTTGGCAATGAGGCTTGGGGCTCTGCTGAAATCCAAAGGAAAGGAGAAGGACAAGCCTCAACCCCCCAGCAAGCCTGAAGTCAGTTTTAATTTGTTGAACACTTTATGTAATGGTGGAATCACCAAACAGAAGCCACCTTCTGATGGGGTACACAGAATTCGTGTAGATTTTAAGCACGATTGTGAAGTAGAGAATGTATGGGACATGGGAGGTATCAGCCTGCTGACAACTGCACCTGTCACCCCACGTGTTGTCTGCTTTCTCTGTGCCAGCAGTGGTCATGTTGAGTTTGTTTATTGCCAGGTGTGCTGTGAACCATTTCACCGGTTCTGCCTAGAGGAAAGAGAGAGACCTTCTGAAGACCAGATTGAAAACTGGTGTTGCCGTCATTGCAAGTTCTGTCATGTATGTGGGAGACAGCAGCAGGCTACCAAGGAGAGCATCGGCAGGCAAAACACTATTTCTGACATGAGCCTAAAGCAGTTACTGGAGTGTAACAAGTGCCGCAACAGCTACCATCCGGAGTGCCTCGGACCAAATTACCCTACCAAACCAACCAAGAAGAAGAGAGTATGGATTTGCACAAAATGTGTAAGATGTAAGAGTTGTGGTTCCACTACACCTGGGAAGGGCTGGGATGCACAGTGGTCACATGACTTCTCCCTGTGCCATGACTGTGCCAAACTGTTTGCTAAGGGAAACTTCTGCCCTTTGTGTAATAAGTGCTATGATGATGATGATTATGAAAGCAAGATGATGCAGTGTGGGAAGTGTGACCGCTGGGTACATTCCAAATGTGAGAACCTGACAGATGAAATGTATGAGATTCTCTCAAATCTTCCGGAAAGTGTGGCCTACACTTGTATAAACTGTACAGAGAGACACCCTGCTGAGTGGAGGATGGCACTGACAAATGAACTGCAGGCCTCCCTCAGATATGTACTAACAGCACTTCTGAATTCCCGTACCTCTAGCCACCTGCTGCGCTGTCGGCAGGCAGCAAAACCACCTGATTTAAATCCAGAACCAGATGAGAATATGCCATCCCGTAGCTCTGCTGAAGGACCAGACCCTCCTATTCTGACTCAGGTCGGCAAGCAAGATGAGCAGCCACCTCTCGATCTAGAGGGAGTTAAAAGGAAAATGGACCACGGCAAGTACAAATCAGTGCTGGAGATGAGTGATGACATTGTGAGAATTATCCAGGCTGCGATGAATGCAGATGGGGGCCAGCCAGAGCTGAAGAAGGCAAACAGTATGGTGAAATCTTTCTTTACAAGGCAAATGGAGCGTGTTTTTCCATGGTTTAGTGTGAAGAAGTCAAGGTTTTGGGAGCCTAACAAAGTTACTAGCAACAGCAGCATGTTGCCCAATGCAGTGCTTCCCCCATCTCTGGACCACAACTATGCTCAGTGGCAGGAAAGGGAAAACAGATTGGCAATGCAGCCAGTGCTGATGAAGAAAATAATCCCTGCTCCAAAGCCTAGATCTCCAGGGGACCCAGAATCTCCACAGCCAGTACAACCATCAACCCCACCAGCACCAACCACAGAGCTCAACAGGGAGGAGAGTCCAGAACTTCCTCCTCCACCAGGGTTGGAAGATAACCGGCAGTGTGCTTTGTGCCTAAAGTATGGTGATGACAATGCCAATGATGCTGGTCGGCTGCTTTATATAGGACAGGATGAGTGGACACATGTAAACTGTGCCTTGTGGTCAGCAGAGGTATTTGAAGATGATGATGGCTCTCTAAAAAATGTTCACATGGCTGTTATCAGAGGCAAGCAGCTGCGTTGTGAATTGTGCCTAAAGTTGGGTGCCACAGTTGGCTGCTGCCTAACTTCTTGTACTAGCAACTACCATTTTATGTGCTCACGGAAAAAGAACTGTGTATTCTTAGAAGACAAAAAGGTTTACTGCCAGAAACACAAGGATTTAATTAAAGGAGAGATTGTTTCTGATAATGGCTTTGAGGTCCTACGGAGAGTTTTTGTTGATTTTGAAGGGATCACCCTACGCAGAAAGTTTCTAAATGGGTTGGAACCAGATAATATCCACATAATGATTGGTTCCATGACCATTGACTGCCTTGGAATTCTGAGTGATCTCTCAGACTGTGAGCAGAAACTTTTCCCCATTGGATATCAGTGTTCCCGTGTGTACTGGAGTACAACAGATGCCCGTAAGCGTTGTGTGTATACATGCAAGATTCTTGAATGTCGCCCTCCACCTGCTGATCCTGATATTAACAGCACAGTACAACATGAGGAGAACCGCACAATTGCACACAGCCCCCAAAGCCTCCATAGTGATGTACAGGAAAATCAGAGCACAGATGGTATAAAATGTATTGAGACTCTTTGCCTCTCATCTCCGGATTCAGTCAGTGCCGCCTCAGTTACCAAACCCTGGGAAGTAGGACGACCTTCTGGATGTAGAACCCATATACCTCGCTATTCCCCATCACAAAGGTCACCTGGATCTCGACCTCTGCCATCAGCTGGAAGTCCATCTCCAGTTACTCATGAGATTGTGACTGTTGGGGACCCGCTTCTATCTTCTGGCCTACGCAAAATTGGTTCAAGAAGGCATAGTTCCTCCTCTTTATCACCCCAGCAGCATAAAAAAATCTTCTCCCCTCATCCACAGACTGATATATCTAGATTTGGCCAACCTCTGCAAGGTATTCCGGTAAACTCTCTTGAAAACAGTGGAAATGGAGACCCTGTGTGTATAGGAGCATCTACAATATCAAGTAAGAGTAGTTGTTCACCAAACACTGGCCAGAAAGCCATAGAATGTAAACTGGAGAAGGCACCAGAAGCAAGACGAACTGGTTTCCTGGAAACCCCTTCAAAAGTCTCCACCCCCAAAACAGAAAAGGTAAAAACAGCTAGTCCAAGAGTTTCTGATCCTTCCTCTGAACATCCAAGCCCCAAGGTTCCCTCTCAAGTGCAGGAGATGACAGCAGATGCTAGCAAAAACAAAGCTGGGTGTTTGAAGGACAGTTCTCCAGCACTTTTAAACTTTAAAACTTCATCCAATATGCAGCACCAAAAAAAAAAAAAAA	NCBI Nucleotide >AF373874\|Xenopus laevis Mll protein (Mll) mRNA, partial cds CGTATCGACGATTCTGAGGTGGTCGATGCCACAATGCATGGAAACGCAGCTCGCTTTATCAACCACTCTTGTGAGCCCAACTGCTACTCTAGAGTCATCCCTATCGATGGTCAGAAGCACATTGTCATCTTTGCCATGCGAAAAATTTACAGAGGGGAGGAGCTTACTTATGACTACAAGTTTCCCATTGAGGATGCAAACAACAAGTTGGCCTGTAACTGCGGGACCAAGAAATGTCGCAAGTTCCTGAACTAAACTACGATTCTTCTGTCACCTAAATTAAGTACAAAGTAGGCATTTGCTCTGTTACTTACACAGGTCTGGCCTGTTTCTTTTTAAATAAGCAGTCCGTACCTTCACTGCTTCAGTGGCCATGAATGCAACGCTACTCTGTCTACTTCTAAATAACACACAGTGCTGTATAGTGATGCTGAGTATATTTATACACTATAGGGAGCATGCTGTGCTGTATAATTATGCTAGAGTATTGCCTGTACATCATTTTGATGTCCTTTGGC
Protein		NCBI Protein >AAI55711\|mll protein [Xenopus (Silurana) tropicalis] MAHSCRWRFPARPGTGRRLGARHRLSAILIDDVSEYRSNPGASGSAGASSAGTLAPGGPGNCLGVALGFDAALQVSAAIGNNLRRFRDVSGGSSGEEEQFLGFGSDEEVKGRSPAKSPKDQTTQRKPRGRPRNSLSRCSDASSNLCENTTSTLNKQETRLLDKVKKPESKTEEKKRGRPPAHGNVKFKLPQEKRDGTESIKAPCEEKSKRRKPSATFQHAAKIKKLRAGKLSPLKSKFKSNKLKLGRKGGVSIVRRRGRPPSSERFKTDTHGSFPKQVPTDRSQRGNKDVSPQPSKEDTRVSVRQSPRRMKPVRIIPSSKRTDTAIAKQLLQKAKKGAQKKMELEAAKLQGRKGGTQLKNIRQFIMPVVSTVSSRIIKTPRRFIEDEDYEPPIKIARLESAPNGSRFSTASCGSSEKSSAASQQSSQATSDDSRSSSPSVDTSTESQASEETPVVSEPQGRVAETITSVPTQQQPLESNGVRTRRLPVCNKNFSSRPAKKIVLRPSFQQKSSVSPPPPLLSPPTPLQPSASLPDHTPWLMPAIPMATPFISASRMHEKRRSILREPTFRWTSLKHSRLESQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGLATASGFPSHTVVGPGRLFSHIHSSGARFDVHKRSPLLRAPRFTPSEAHSRIFESVTLPPSAGRASGTSSMMGISRRSKRRVFNPIRSSEPKSPSHSMRTRSRRVGNSSLSVLASPPSSSLTDISVSPLATSALNPSFPFSSSSVTPASVDIAEKIQKPRKPTSTPAEHFTSSPSSSPALFPWFPSSVQMEKGKSKNRGSVESSKEREVEKNREKDREKENSRDSRRDKRKKSSDSGCKISRERNDEEGIVTATQIKMSVRKKPVTVESNVDISPASIHTDQIPAKNKISKKGRPVSEKTELDTCAKSPTAETQAQLPAQPVSALKHPSTSISSMLAQADKFPVSDKHVATLLRKAKAQLCKIEKSKFLKQTDQPKAQGQESDSSEASVRGPRIKHVCRRAAVALGRKRAVFPDDMPTLSALPWEEREKVLSSMGNDDKSSIAGSEDADQPAPPLKPIKQITRNKAQQEPPVKKGRRSRRCGQCPGCQVPDDCGICTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAAKKKERKCKVTEKKELPPVKSPSELIVKPVSAPGTSSPPVQEEPATPSLPQKKNEPPKKQTEEKSEEQIPAASTSETKQSPNSRKTTKQPPSQPSTTIAMTPLTATPSTKKEAPKPIPPESRKKQPPVLPDNTSTEQNKQKKLAMRLGALLKSKGKEKDKPQPPSKPEVSFNLLNTLCNGGITKQKPPSDGVHRIRVDFKHDCEVENVWDMGGISLLTTAPVTPRVVCFLCASSGHVEFVYCQVCCEPFHRFCLEERERPSEDQIENWCCRHCKFCHVCGRQQQATKESIGRQNTISDMSLKQLLECNKCRNSYHPECLGPNYPTKPTKKKRVWICTKCVRCKSCGSTTPGKGWDAQWSHDFSLCHDCAKLFAKGNFCPLCNKCYDDDDYESKMMQCGKCDRWVHSKCENLTDEMYEILSNLPESVAYTCINCTERHPAEWRMALTNELQASLRYVLTALLNSRTSSHLLRCRQAAKPPDLNPEPDENMPSRSSAEGPDPPILTQVGKQDEQPPLDLEGVKRKMDHGKYKSVLEMSDDIVRIIQAAMNADGGQPELKKANSMVKSFFTRQMERVFPWFSVKKSRFWEPNKVTSNSSMLPNAVLPPSLDHNYAQWQERENRLAMQPVLMKKIIPAPKPRSPGDPESPQPVQPSTPPAPTTELNREESPELPPPPGLEDNRQCALCLKYGDDNANDAGRLLYIGQDEWTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCELCLKLGATVGCCLTSCTSNYHFMCSRKKNCVFLEDKKVYCQKHKDLIKGEIVSDNGFEVLRRVFVDFEGITLRRKFLNGLEPDNIHIMIGSMTIDCLGILSDLSDCEQKLFPIGYQCSRVYWSTTDARKRCVYTCKILECRPPPADPDINSTVQHEENRTIAHSPQSLHSDVQENQSTDGIKCIETLCLSSPDSVSAASVTKPWEVGRPSGCRTHIPRYSPSQRSPGSRPLPSAGSPSPVTHEIVTVGDPLLSSGLRKIGSRRHSSSSLSPQQHKKIFSPHPQTDISRFGQPLQGIPVNSLENSGNGDPVCIGASTISSKSSCSPNTGQKAIECKLEKAPEARRTGFLETPSKVSTPKTEKVKTASPRVSDPSSEHPSPKVPSQVQEMTADASKNKAGCLKDSSPALLNFKTSSNMQHQKKKK	NCBI Protein >AAQ02781\|Mll protein [Xenopus laevis] RIDDSEVVDATMHGNAARFINHSCEPNCYSRVIPIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDANNKLACNCGTKKCRKFLN

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.39536	Xl.34942 [+] Xl.48143 Xl.68477
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	KMT2A
mouse		MGI	Mll1	All(18) Targeted, knock Out(4) Targeted, other(12)
zebrafish			mll

Publications
First:		WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development. [Cell 2005]
Most recent:
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		DNA binding calcium ion binding glucan 1,4-alpha-glucosidase activity More[+] zinc ion binding
Biological:		DNA recombination DNA repair regulation of transcription, DNA-dependent
Cellular Component:		nucleus
EC:		glucan 1,4-a-glucosidase
KOG:		[K] Transcription factor TCF20

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.42957.1.A1_s_at [+] Str.49146.1.S1_s_at Str.49146.2.S1_s_at Str.39536.1.S1_at Str.24660.1.S1_s_at Str.49223.1.A1_at StrEns.1379.1.S1_s_at
Affymetrix 2.0			Xl2.48143.1.S1_at [+] Xl2.34942.1.A1_at Xl2.34942.1.S1_at

Symbol legend[+]