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Summary Expression Gene Literature (4) GO Terms (15) Nucleotides (121) Proteins (32) Interactants (84) Wiki
XB-GENEPAGE-922911
Gene Symbol:
kmt2a

Gene Name:
lysine methyltransferase 2A

Synonyms:
mll1 , hrx , trx1 , all-1 , cxxc7 , htrx1 , knt2a , mll1a , mll/gas7 , tet1-mll ( Add synonyms , Nomenclature history )

Gene Function:
zinc finger transcription factor

Protein Function :



Interactants:
Loading ...

Diseases: 


OMIM:
LYSINE-SPECIFIC METHYLTRANSFERASE 2A; KMT2A [+]

External Links:
 
Xenbase Gene ID XB-GENE-922912 XB-GENE-6256014 XB-GENE-17331414
Gene Symbol kmt2a kmt2a.L kmt2a.S
Chromosome Chr07 chr7L Scaffold80
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100135006
403379
108705229
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. TrEMBL NCBI Protein TrEMBL
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine kmt2a kmt2a.L kmt2a.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, KMT2A Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Kmt2a MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Kmt2a Ensembl
zebrafish
kmt2a Ensembl
chicken
GEISHA KMT2A Ensembl
fruit fly
worm
Publications
First WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development., Cell 2005    
Most Recent Cryo-EM structure of the human MLL1 core complex bound to the nucleosome., Nat Commun 2019  
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 15 terms 0 term 5 terms
PANTHER kmt2a
KEGG Pathways K09186
KOG [K] Transcription factor TCF20
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks kmt2a
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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