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Summary Expression Gene Literature (2) GO Terms (12) Nucleotides (277) Proteins (31) Interactants (266) Wiki
XB-GENEPAGE-923355
Gene Symbol:
sae1

Gene Name:
SUMO1 activating enzyme subunit 1

Synonyms:
Aos , Aos1p , Sua1p ( Add synonyms , Nomenclature history )

Gene Function:
ubiquitin-protein ligase

Protein Function :
The heterodimer acts as an E1 ligase for sumo1, sumo2, and sumo3. It mediates ATP-dependent activation of sumo proteins followed by formation of a thioester bond between a sumo protein and a conserved ...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-923356 XB-GENE-923367 XB-GENE-17345580
Gene Symbol sae1 sae1.L sae1.S
Chromosome Chr08 chr8L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 549624
443558
mRNA RefSeq RefSeq
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine sae1 sae1.L sae1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SAE1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Sae1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Sae1 Ensembl
zebrafish
ZFIN, AGR sae1 ZFIN Ensembl
chicken
GEISHA SAE1 Ensembl
fruit fly
worm
Publications
First SUMO2/3 modification of cyclin E contributes to the control of replication origin firing., Nat Commun 2013          
Most Recent Genome-wide identification of thyroid hormone receptor targets in the remodeling intestine during Xenopus tropicalis metamorphosis., Sci Rep 2017              
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 12 terms 4 terms 0 term
PANTHER sae1
KEGG Pathways K10684 K10684
KOG [O] SMT3/SUMO-activating complex, AOS1/RAD31 component
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks sae1
ORFs sae1 ORF1 sae1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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