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Summary Expression Gene Literature (9) GO Terms (7) Nucleotides (143) Proteins (14) Interactants (383) Wiki
XB-GENEPAGE-940705
Gene Symbol: prkra

Gene Name: protein activator of interferon induced protein kinase EIF2AK2

Synonyms: rax , pact , dyt16 ( Add synonyms , Nomenclature history )

Gene Function: Staufen and related double-stranded-RNA-binding proteins

Protein Function :
Activates eif2ak2/pkr in the absence of double-stranded RNA (dsRNA), leading to phosphorylation of eif2s1/efi2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA product...[+]

Interactants: Loading ...
Disease Ontology: dystonia 16

OMIM Diseases: DYSTONIA 16; DYT16

 
Xenbase Gene ID XB-GENE-940706 XB-GENE-940708 XB-GENE-17343860
Gene Symbol prkra prkra.L prkra.S
Chromosome Chr09 chr9_10L
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein RefSeq TrEMBL TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine prkra prkra.L prkra.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards PRKRA OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Prkra MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR prkra ZFIN Ensembl
chicken
fruit fly
worm
WORMBASE
Publications
First A conserved double-stranded RNA-binding domain., Proc Natl Acad Sci U S A 1992  
Most Recent The role of Xenopus Rx-L in photoreceptor cell determination., Dev Biol 2009              
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 7 terms 0 term
PANTHER prkra
KEGG Pathways K18420
KOG [UK] Staufen and related double-stranded-RNA-binding proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
ORF prkra.L ORF1
Affymetrix 1.0 Str.5894.1.S1_at [+] Xl.852.1.S1_at
Affymetrix 2.0 Xl2.852.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.12.0


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