[provisional- machine annotated only] Gene Symbol: hk1 [Predicted: Source is Human Entrez Gene] Gene Name: hexokinase 1 [Predicted: Source is Human Entrez Gene] Synonyms: Hexokinase, Hexokinase 1 Add Xenopus synonyms Gene Function: Hexokinase Interactants: gck(3) , ins(2) , slc2a1(2) , bcl9(1) , cftr(1) , figla(1) , g6pd(1) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001102731|Xenopus (Silurana) tropicalis hexokinase 1 (hk1), nuclear gene encoding mitochondrial protein, mRNA GGCTGCTGTATAATTGGGCACAAGCACATTGGGTTCCTCTGCCAGTATATAGGCGCCTGTGAGCTCTGCCGTTACCGACAAGATGATTGCTGCCCAGCTGCTAGCATATTACTTCACAGAACTTAAAGATGATCAGCTGAAGAAGATTGATAAATATTTGTACTCTATGCGCCTCTCCGATGAAACCTTACTGGATATTATGGGGAGGTTCCGAGCAGAAATGGCAAATGGTCTTTCAAGGGACACAAATCCCACAGCAATTATCAAGATGCTGCCAACATTTGTAAGATCAATTCCTGATGGAACAGAAAAGGGAGATTTCATTGCTCTGGATTTGGGTGGATCTCATTTCCGCATTTTGAGAGTGAAAGTTTCGCATGAGAAGAAGCAGACGGTTCAGATGGAGAGTGAGATCTATGACACACCAGAGGATATTATCCATGGCAGTGGTACCCGACTTTTTGACCATGTTGCTGAATGCCTTGGAGACTTCATGCAGAAGAAGCAGATCAAAGACAAAAAGCTGCCTGTTGGATTTACCTTCTCCTTCCCTTGTATACAAACCAAAATAGATGAGGGTGTACTAGTTACCTGGACCAAGAGATTCAAAGCCAGTGGGGTTGAGGGAATGGATGTTGTGAAACTGCTAAATAAGGCGATCAAGAAACGCGGGGACTATGAGGCAGATATAATGGCTGTCGTGAATGACACAGTTGGGACAATGATGACTTGTGGGTTTGATGACCAGAGATGTGAAGTCGGTATAATTATAGGTACTGGGACCAATGCTTGCTACATGGAAGAGCTGAGGCACATTGATATGGTGGAAGGGGATGAGGGTCGAATGTGCATTAACACTGAGTGGGGAGCATTTGGTGACGATGGGTGTCTGGAGGACATCAGGTCGGAGTTCGACAGAGAGATAGACAGAGGTTCACTCAATCCAGGAAAACAGCTGTTTGAAAAGATGGTCAGCGGCATGTACATGGGGGAACTTGTCAGACTTATCCTGGTAAAAATGGCCAAAGAAGGACTCCTATTTGAAGGGAGAATTACTCCTGAACTTCTGACCAGAGGAAAATTTGAAACAAAGCATGTTTCTGCAATCGAGAAGAGCAAAGAAGGTTTAAGCAAAGCCAAAGACATACTGACCAGACTTGGGGTGGAGCCATCTCACGAAGACTGCATTGCTGTGCAGCATGTATGTACAATCGTGTCCTTCCGCTCTGCTAATCTAGTTGCTGCTACGCTTGGTGGAATCCTCATACGACTGAGGGACAATAAAGGGGTTCCCAGGCTGCGTACTACTGTGGGCATCGATGGATCCTTATACAAGATGCATCCACAATATGCCAGGCGCTTACACAAAACAGTAAGGCGACTGGTTCCTGAGTCGGATGTGAGATTCCTCTTATCAGAGAGTGGAAGTGGCAAAGGAGCTGCCATGGTGACTGCGGTGGCATACAGGCTGTCAGAGCAGAGAAGGCAGATCGATGAGACCTTAGAAGAGTTCAAGCTCAGCCGTGAACAGTTGCTTGAGGTTAAGAGGAGGATGCGGATTGAAATAGAGAATGGACTCAGGAAAAAGACCCATGAATCAGCAAAGGTTAAAATGTTGCCAACGTATGTAAGGAGTACACCCGATGGTACAGAAAATGGAGACTTTCTGGCTCTGGACCTTGGTGGCACAAACTTTAGAGTTTTACTTGTGAAAATTCGAAGTGGAAAAAGAAGAACCGTGGAAATGCACAATAAAATTTACGCCATCCCTATAGATGTCATGCAGGGGACAGGGGAAGAGCTCTTTGATCACATTGCTCATTGTATTTCTGATTTCCTGGATTACATGGGAATAAAGGGAGCAAGACTTCCGCTGGGCTTCACTTTCTCGTTCCCCTGCATGCAGACCAGCTTGGATGCTGGCATCTTAGTCACATGGACCAAAGGTTTCAAGGCCACTGATTGTGAAGGAGAAGATGTGGTTAATTTATTAAGAGAAGGAATTAAGAGAAGAGAGGAGTTTGACCTGGATGTGGTTGCGATTGTGAATGATACAGTAGGAACCATGATGACCTGTGCATATGAAGATCCAAACTGTGAAATTGGTCTCATTGTGGGGACTGGAAGCAATGCATGCTACATGGAAGAAACAAAGAATATAGAAATGGTGGACGGAGACCAGGGAAGAATGTGTGTGAACATGGAATGGGGAGCGTTTGGGGACAATGGTTGCCTTGATGATATCCGCACAGTCTATGATAAGGCTGTTGATGATTTGTCATTAAATTCAGGAAAACAGAGGTACGAGAAGATGATCAGTGGCATGTATTTAGGAGAAATTGTGCGCAACATATTAATTGACTTCACAAAAAGAGGATTTCTGTTCAGAGGGCAGATTAGTGAGGCACTGAAAACCACAAGTATCTTTGAAACCAAATTCCTTTCCCAAATTGAGAGTGATAGATTAGCGCTTCTCCAAGTCCGATCTATCCTTCAGCAACTAGGTCTAAACAGCACCTGCGATGACAGTATCATTGTAAAGGAGGTGTGTGGTGCTGTATCAAGAAGGGCAGCGCAGGTGTGCGGGGCAGGCATGGCAGCGGTCGTGGATAAAATCCGAGAGAACAGGGGCTTAGACCATCTGGACGTCACAGTTGGAGTTGATGGAACATTATATAAATTACATCCACACTTCTCCAAAATCATGCACCAAACAGTTAAAGACCTTGCCCCGAAGTGCAACGTTTCTTTCCTCCTCTCGGAGGATGGGAGCGGTAAAGGAGCGGCTCTGATCACTGCTGTGGCCTGCAGACTCCGCAGTAGTGAACAAAATTAGATCCTGAACATCTCCCTTGTATCGTCCTGCCTTTTTCAGCACTTTCATTTCAAGCTGTAACCGTAACAAGGCTGCTCAGTTCTAGCCATGATGTCCATAGGAAGATAATAAGGGGAATTAAGCGGTCACAGTAGAAAGTATGTGCTAGAAGACTGCACTCTGTGTATCGGTCCCCCATATAAGGGGGTTGTTTGCCATTAACTTAACTATTAGTATGTTATAAAATGTCCTGTTTTCAGCAATATTCCAACTGGTCTTCATTTTTTACATGCATTTTAGTTTTTGAATTATTGGTCCTTGTTTTCTGACTCTTCCAGGCTTCTCATGGGGGTCACAGACATGAGTAATGCTACTTTCTATTATTTATCTTTCTATCTATCTATCCATCTTTCAAACCACTGCCTGGTTGCTAGGGTACTTTGGACCCTAGCAACCAGACAGCTGCTGAAATTCCAAACTGGAGAGCTGCTGAACAAAAAATTCAAACATCATAACAAAAAAAATGAGGACCAATTGCAAATTGTCTCATAGTATCCCTGTCTCCATCATGACAAAAGTTATTTTAAAGGTGAACAACCCCTATAACATGCAGCCAACCTGTTGGTCAGTGATAATGATTTATAATTTATTCTTTTATATGTTATTTATCAGTTTGTAAGCGCCCAACAATGTAATATTCTGTTTCTTGCTCTTCATGAGTTCAGTCCATTTTTTTAAGTGCAACTGTTGTCACTGGAATTTCCTTAGCCGTAAACTTAGAAGACACGATATTCTGTGATATGCAGTGATTTTAGGCCAAATCTCATTTTACCTTTTAAACAAATCATTATTTGATAAATTATGTAGCCCCTCTGCATGTTGCTGAACTGCAAATCCCTGCAGCAGTTGATGGGAATAGTAGTTGAGTAAGTAGCAGAGGGGTGCAGGGTGGGATTAGAATGTATAACGGCTTGCATTCCTGAGCTCACAGAACATCTTCCCAAATCATGTACCACTGGGGACACGTCTGTTACATGTGCTACTATAGCAATTCCCAAAGCTTGTATGAATAGTGTTGTGTCAGTTGTATGTACCAAAGCCCATGCGTATGGTTTTGTTTCAGCTTGTTTATTTCCGGGGAGGCATCGTCATTGAACTGCACAAAGCAGGTCCCAGGAACTGAAAGGGTTGGACACTTTTATATGAATATTATTTGATTTTGCACTGTGATTGAATGTGTTGAGATGGTGTGAATTTCATTTTTAAATGTCTGTATTAGAAAACCAAGCCTGATAAATCCAGTGTAAAACAGAAAGAGATATATTTGCCACTCTAGGTCACTAATGTTATTTATCGACTTAATAAACTTTTTCCAATGTGAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001103186|Xenopus laevis hexokinase 1 (hk1), nuclear gene encoding mitochondrial protein, mRNA GATTTGGCTGCTGTATAACTGGGCACAAGCACATTGGGTCCCTCTGGCAGTCTATAGGCACCTGTGAGCTTAGACGATACCGACAGGATGATTGCTGCCCAGCTGCTGGCCTATTACTTCACTGAACTGAAAGATGATCAGCTCAAGAAGATTGATAAATATTTGTACGCTATGCGCCTTTCCGATGAAACCTTACTGGATATTACGGGGAGGTTCAGAGCAGAAATGGCAAATGGTCTTTCAAGAGACACAAACCCCACAGCAATTATTAAGATGTTGCCAACATTTGTAAGATCGATCCCCGATGGAACAGAAAAGGGAGATTTCATCGCTTTGGATTTGGGTGGATCTAATTTTCGCATTTTGAGAGTGAAGGTCTCGCATGAGAAGAAGCAGACAGTCCAGATGGAGAGTGAGATCTATGATACACCAGAGGACATTATCCATGGTAGTGGTACTAGACTTTTTGACCATGTTGCTGAATGCCTCGGAGACTTCATGCAGAAGAAACAGATCAAAGATAAAAAGCTGCCTGTTGGATTTACCTTCTCCTTCCCTTGTATACAAACCAAAATAGATGAGGGTGTACTGGTTACCTGGACCAAGAGATTCAAAGCCAGTGGGGTTGAGGGAATGGATGTTGTAAAACTGCTAAACAGGGCAATCAAGAAACGAGGGGACTACGAGGCAGATATAATGGCGGTCGTGAATGACACAGTTGGGACAATGATGACTTGTGGGTTTGATGACCAGAGATGTGAAGTTGGTATAATCATAGGTACTGGAACCAACGCTTGCTACATGGAGGAGTTGAGGCACATTGATATGGTGGAGGGGGATGAGGGTCGAATGTGCATTAACACTGAGTGGGGAGCATTTGGTGATGAAGGGTGTCTGGAGGACATCAGGACAGAATTTGACAGAGAGATAGACCGTGGTTCACTTAATCCAGGAAAACAGCTGTTTGAAAAGATGGTCAGCGGAATGTACATGGGGGAACTTGTCAGACTTATCTTGGTAAAAATGGCGAAAGAAGGACTCCTGTTTGAAGGAAGGATCACTCCGGAGCTTCTGACCAGAGGGAAATTTGAAACAAAGCACATCTCTGCAATTGAGAAGAGCAAAGAAGGTTTAAGCAAAGCTAAAGACATATTGACCAGGCTTGGGGTAGAGCCATCTCATGAAGACTGCATTGCTGTGCAGCATGTATGTACAATCGTTTCCTTCCGCTCTGCTAATCTAGTTGCTGCTACACTTGGTGGAATCCTGATACGGCTACGAGACAATAAAGGGGTCCCCAGGCTCCGTACTACTGTGGGCATTGATGGATCCTTGTACAAGATGCATCCACAATATGCCAGGCGCTTGCATAAAACAGTAAGACGATTGGTTCCAGACTCGGATGTGAGATTCCTCTTATCCGAGAGTGGCAGTGGTAAAGGAGCTGCCATGGTAACTGCGGTGGCATACAGGCTGTCAGAACAGAGACGGCAGATTGACGAGACCTTAGAAGAGTTCAAGCTCAGCCGTGAACAGTTGCTTGAAGTGAAGCGGAGGATGCGGATTGAAATGGAGAATGGACTCCGGAAAAAGACTCATGAATCTGCAAAGGTTAAAATGTTAGCGACATTTGTAAGGAGTACACCAGATGGCACAGAAAATGGAGACTTTCTGGCACTGGACCTTGGTGGTACAAACTTTAGAGTTTTACTTGTGAAAATTCGAAGTGGGAAAAGAAGAACCGTGGAAATGCACAATAAAATCTATGCCATCCCTACAGATGTCATGCAGGGGACAGGGGAAGAGCTGTTTGATCACATTGTTCATTGTATTTCTGATTTCCTGGATTACATGGGAATTAAGGGAGCAAGACTTCCCCTGGGCTTCACTTTCTCGTTCCCCTGCAAGCAGACCAGCTTGGATGCTGGCATATTAGTCACATGGACCAAAGGTTTCAAGTCCACTGATTGTGAGGGAGAAGATGTGGTTAATCTATTAAGAGAAGGAATTAAGAGAAGAGAGGAGTTTGACCTGGATGTGGTTGCGATTGTGAATGATACAGTAGGAACCATGATGACCTGTGCATATGAAGATCCAAACTGTGAAATTGGTCTGATCGTTGGGACTGGCAGCAATGCATGCTACATGGAAGAGACAAAGAACATAGAAATGGTGGATGGAGAACAGGGGAGAATGTGTGTGAACATGGAATGGGGAGCATTTGGGGACAATGGATGTCTTGATGATATCCGCACAGTCTATGACAAGGCTGTCGATGAATTGTCATTAAATTCAGGGAAACAAAGGTATGAGAAGATGATCAGCGGCATGTATTTAGGAGAAATTGTGCGCAACATATTAATTGACTTCACAAAAAGAGGATTCCTGTTCAGAGGACAGATTAGCGAGGCGCTGAAAACCACAAGTATCTTTGAAACCAAATTCCTTTCCCAAATTGAGAGTGACAGATTAGCTTTGCTCCAAGTCCGGTCTATCCTTCAGCAATTAGGTCTGAACAGCACCTGCGATGACAGTATAATTGTAAAGGAGGTGTGTGGAGCTGTATCTAGAAGGGCAGCCCAGTTGTGCGGTGCAGGCATGGCAGCCGTTGTGGATAAAATCCGAGAAAACAGGGGCTTAGACCATCTGGACGTCACAGTTGGAGTTGATGGAACATTATATAAATTACATCCACACTTCTCCAAAATCATGCACCAAACAGTTAAGGACCTCGCCCCGAAGTGCAATGTCTCTTTTCTCCTCTCGGAGGATGGGAGCGGTAAAGGAGCGGCTCTGATCACTGCTGTGGCCTGCAGACTCCGCACCGAACAAAACTAAATCCTGATCATCTTCCTTGTATGCTCCTGCCTTTTCAGCACTTTCATTTCAAGCAGTAACCGTAACAAGGCTGGTCAGCTCCAGCCATCATGTCCATAGGAAGATAATATGGGAAAATAGGAGGTCACAGTAGAAAGTACTTGCTAGAAACGTGCACTCCTCAGTATGAGTCCCACAGTTAAACAGGAAGTCTACCTTTAACTTAACTATTAGTATGTTATACAATGTCCTGTTTTAGCAATTTTTCAATCAGTCTTCATTTTTTAAAAAAAAAAAAAAA
Protein		Refseq >NP_001096201|hexokinase 1 [Xenopus (Silurana) tropicalis] MIAAQLLAYYFTELKDDQLKKIDKYLYSMRLSDETLLDIMGRFRAEMANGLSRDTNPTAIIKMLPTFVRSIPDGTEKGDFIALDLGGSHFRILRVKVSHEKKQTVQMESEIYDTPEDIIHGSGTRLFDHVAECLGDFMQKKQIKDKKLPVGFTFSFPCIQTKIDEGVLVTWTKRFKASGVEGMDVVKLLNKAIKKRGDYEADIMAVVNDTVGTMMTCGFDDQRCEVGIIIGTGTNACYMEELRHIDMVEGDEGRMCINTEWGAFGDDGCLEDIRSEFDREIDRGSLNPGKQLFEKMVSGMYMGELVRLILVKMAKEGLLFEGRITPELLTRGKFETKHVSAIEKSKEGLSKAKDILTRLGVEPSHEDCIAVQHVCTIVSFRSANLVAATLGGILIRLRDNKGVPRLRTTVGIDGSLYKMHPQYARRLHKTVRRLVPESDVRFLLSESGSGKGAAMVTAVAYRLSEQRRQIDETLEEFKLSREQLLEVKRRMRIEIENGLRKKTHESAKVKMLPTYVRSTPDGTENGDFLALDLGGTNFRVLLVKIRSGKRRTVEMHNKIYAIPIDVMQGTGEELFDHIAHCISDFLDYMGIKGARLPLGFTFSFPCMQTSLDAGILVTWTKGFKATDCEGEDVVNLLREGIKRREEFDLDVVAIVNDTVGTMMTCAYEDPNCEIGLIVGTGSNACYMEETKNIEMVDGDQGRMCVNMEWGAFGDNGCLDDIRTVYDKAVDDLSLNSGKQRYEKMISGMYLGEIVRNILIDFTKRGFLFRGQISEALKTTSIFETKFLSQIESDRLALLQVRSILQQLGLNSTCDDSIIVKEVCGAVSRRAAQVCGAGMAAVVDKIRENRGLDHLDVTVGVDGTLYKLHPHFSKIMHQTVKDLAPKCNVSFLLSEDGSGKGAALITAVACRLRSSEQN	Refseq >NP_001096656|hexokinase 1 [Xenopus laevis] MIAAQLLAYYFTELKDDQLKKIDKYLYAMRLSDETLLDITGRFRAEMANGLSRDTNPTAIIKMLPTFVRSIPDGTEKGDFIALDLGGSNFRILRVKVSHEKKQTVQMESEIYDTPEDIIHGSGTRLFDHVAECLGDFMQKKQIKDKKLPVGFTFSFPCIQTKIDEGVLVTWTKRFKASGVEGMDVVKLLNRAIKKRGDYEADIMAVVNDTVGTMMTCGFDDQRCEVGIIIGTGTNACYMEELRHIDMVEGDEGRMCINTEWGAFGDEGCLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYMGELVRLILVKMAKEGLLFEGRITPELLTRGKFETKHISAIEKSKEGLSKAKDILTRLGVEPSHEDCIAVQHVCTIVSFRSANLVAATLGGILIRLRDNKGVPRLRTTVGIDGSLYKMHPQYARRLHKTVRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLSEQRRQIDETLEEFKLSREQLLEVKRRMRIEMENGLRKKTHESAKVKMLATFVRSTPDGTENGDFLALDLGGTNFRVLLVKIRSGKRRTVEMHNKIYAIPTDVMQGTGEELFDHIVHCISDFLDYMGIKGARLPLGFTFSFPCKQTSLDAGILVTWTKGFKSTDCEGEDVVNLLREGIKRREEFDLDVVAIVNDTVGTMMTCAYEDPNCEIGLIVGTGSNACYMEETKNIEMVDGEQGRMCVNMEWGAFGDNGCLDDIRTVYDKAVDELSLNSGKQRYEKMISGMYLGEIVRNILIDFTKRGFLFRGQISEALKTTSIFETKFLSQIESDRLALLQVRSILQQLGLNSTCDDSIIVKEVCGAVSRRAAQLCGAGMAAVVDKIRENRGLDHLDVTVGVDGTLYKLHPHFSKIMHQTVKDLAPKCNVSFLLSEDGSGKGAALITAVACRLRTEQN

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.64346 [+] Str.60630	Xl.726
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		2 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	HK1
mouse		MGI	Hk1	All(1) Spontaneous(1)
zebrafish		ZFIN	hk1	1 Lines(s)

Publications
First:		Changes in activity of the regulatory glycolytic enzymes and of the pyruvate-dehydrogenase complex during the development of Xenopus laevis. [Exp Cell Biol 1986]
Most recent:		Comparative genomics approach to the expression of figalpha, one of the earliest marker genes of oocyte differentiation in medaka (Oryzias latipes). [Gene 2008]
		View All Papers

Functional Ontologies
GO: Molecular:		ATP binding hexokinase activity
Biological:		glycolysis
Cellular Component:
EC:		hexokinase
KOG:		[G] Hexokinase

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.30944.1.A1_at [+] Str.11721.1.S1_at	Xl.726.1.S1_at
Affymetrix 2.0			Xl2.726.1.S1_at [+] Xl2.726.1.S2_at

Symbol legend[+]

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   - Literature Or Expression Images