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Summary Expression Gene Literature (11) GO Terms (33) Nucleotides (136) Proteins (35) Interactants (398) Wiki
XB-GENEPAGE-945071
Gene Symbol:
foxo3

Gene Name:
forkhead box O3

Synonyms:
foxo3a , xfoxo3 ( Add synonyms , Nomenclature history )

Gene Function:
forkhead domain transcription factor

Protein Function :
Transcriptional activator that recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3' and regulates different processes, such as apoptosis and autophagy. Acts as a positive regulator of autophagy...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-945072 XB-GENE-945076 XB-GENE-17336905
Gene Symbol foxo3 foxo3.L foxo3.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100125025
444992
108717943
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine foxo3 foxo3.L foxo3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FOXO3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tppp2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Foxo3 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR foxo3b foxo3a ZFIN Ensembl
chicken
GEISHA FOXO3 Ensembl
fruit fly
worm
Publications
First The FoxO-subclass in Xenopus laevis development., Gene Expr Patterns 2004      
Most Recent The regulation of Akt and FoxO transcription factors during dehydration in the African clawed frog (Xenopus laevis)., Cell Stress Chaperones 2020  
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 18 terms 20 terms 4 terms
PANTHER foxo3
KEGG Pathways K09408 K09408 K09408
KOG [K] Transcription factor of the Forkhead/HNF3 family
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks foxo3
Morpholinos (on-target & off-target) foxo3 MO2 , foxo3 MO3 foxo3 MO1 , foxo3 MO2
ORFs foxo3.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info