|
XB-GENEPAGE-946666
Gene Symbol: lrrc6
Gene Name: leucine rich repeat containing 6 Synonyms: ( Add synonyms , Nomenclature history ) Gene Function: Protein phosphatase 1, regulatory subunit, and related proteins Protein Function ![]()
May play a crucial role in regulating cilia motility in pronephric tubules, cloaca and neural tube. May be required for establishing left-right asymmetry of the body plan; controls cell fate and conver...[+]
Interactants: Loading ... ![]() Disease Ontology: primary ciliary dyskinesia 19 OMIM Diseases: CILIARY DYSKINESIA, PRIMARY, 19; CILD19 |
|
Xenbase Gene ID | XB-GENE-946667 | XB-GENE-6487993 | XB-GENE-17331602 | |||||
Gene Symbol | lrrc6 | lrrc6.L | lrrc6.S | |||||
Chromosome | Chr06 | chr6L | ||||||
Molecules | tropicalis | laevis.L | laevis.S | |||||
Gene |
Genomic sequence
![]() |
Genomic sequence
![]() |
||||||
CDS |
Gene model
![]() |
|||||||
Entrez Gene: 394985
|
Entrez Gene: 108719416
|
|||||||
mRNA |
RefSeq
![]() ![]() |
NCBI Nucleotide
![]() ![]() |
||||||
Protein
![]() |
RefSeq
![]() ![]() |
NCBI Protein
![]() ![]() |
||||||
Genomic | tropicalis | laevis.L | laevis.S | |||||
Genome Browser | ||||||||
Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
|
|||||||
More Information |
|
|||||||
Proteomics | tropicalis | laevis.L | laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
|||||||
Data Mining | tropicalis | laevis.L | laevis.S | |||||
XenMine | lrrc6 | lrrc6.L | lrrc6.S | |||||
Phenotype | tropicalis | laevis.L | laevis.S | |||||
Smith Morpholino Screen | ||||||||
Orthology |
|
|||||||
human |
|
|||||||
mouse |
|
|||||||
zebrafish |
|
|||||||
chicken |
|
|||||||
fruit fly |
|
|||||||
worm |
|
|||||||
Publications | ||||||||
First |
ZMYND10 is mutated in primary ciliary dyskinesia and interacts with LRRC6., Am J Hum Genet 2013 ![]() |
|||||||
Most Recent |
A liquid-like organelle at the root of motile ciliopathy., Elife 2018 ![]() |
|||||||
All | View All Papers 1 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | tropicalis | laevis.L | laevis.S | |||||
GO | 6 terms | 0 term | 0 term | |||||
PANTHER | lrrc6 | |||||||
KEGG Pathways | K19753 | |||||||
KOG |
[T] Protein phosphatase 1, regulatory subunit, and related proteins
|
|||||||
Reagents | tropicalis | laevis.L | laevis.S | |||||
CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | |||||
Clones | ||||||||
Dharmacon | Dharmacon | |||||||
Affymetrix 1.0 | Str.20506.1.S1_at | |||||||
Affymetrix 2.0 |
Symbol legend:


