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Summary Expression Gene Literature (2) GO Terms (6) Nucleotides (50) Proteins (20) Interactants (55) Wiki
XB-GENEPAGE-946666
Gene Symbol: lrrc6

Gene Name: leucine rich repeat containing 6

Synonyms: ( Add synonyms , Nomenclature history )

Gene Function: Protein phosphatase 1, regulatory subunit, and related proteins

Protein Function :
May play a crucial role in regulating cilia motility in pronephric tubules, cloaca and neural tube. May be required for establishing left-right asymmetry of the body plan; controls cell fate and conver...[+]

Interactants: Loading ...
Disease Ontology: primary ciliary dyskinesia 19

OMIM Diseases: CILIARY DYSKINESIA, PRIMARY, 19; CILD19

 
Xenbase Gene ID XB-GENE-946667 XB-GENE-6487993 XB-GENE-17331602
Gene Symbol lrrc6 lrrc6.L lrrc6.S
Chromosome Chr06 chr6L
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene: 394985
Entrez Gene: 108719416
mRNA RefSeq NCBI Nucleotide
Protein RefSeq TrEMBL TrEMBL Swiss-Prot NCBI Protein
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine lrrc6 lrrc6.L lrrc6.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards LRRC6 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Lrrc6 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR lrrc6 ZFIN Ensembl
chicken
GEISHA LRRC6 Ensembl
fruit fly
worm
WORMBASE
Publications
First ZMYND10 is mutated in primary ciliary dyskinesia and interacts with LRRC6., Am J Hum Genet 2013    
Most Recent A liquid-like organelle at the root of motile ciliopathy., Elife 2018                              
All View All Papers 1 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 6 terms 0 term 0 term
PANTHER lrrc6
KEGG Pathways K19753
KOG [T] Protein phosphatase 1, regulatory subunit, and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon
Affymetrix 1.0 Str.20506.1.S1_at
Affymetrix 2.0

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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