spast Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Nucleotides (137)

Interactants (0)

XB-GENEPAGE-947838

[provisional- machine annotated only] Gene Symbol: spast [Predicted: Source is Human Entrez Gene] Gene Name: spastin [Predicted: Source is Human Entrez Gene] Add Xenopus synonyms Gene Function: AAA+-type ATPase Interactants:

XB-GENE-947839

XB-GENE-947846

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001016453\|Xenopus (Silurana) tropicalis spastin (spast), mRNA GCGGAGCTGTAGCTCACTGTTCCCGGTGTTATGGCTGTGGGCCCCGTGAATGAATTCTCCGGGCGGAAGAAACGACAAGAAGAAACCGGTGACCCCAGCGGCGGAGACTGGTCCCGGCCCGCCGACGCCTCCTCCTCCTCCAGCAGAGACGCAGGTCCTGCTCGCCCCGCCCTCACTGCATAAGCGGAACCTTTACCTGTTCTCCTACCCCCTGCTCGCCGCTTTCTCCCTGCTACGCTTCCTGGCTTTTCAGCTGGGGCTGCTGTTCGTTTGGTTTTGTGAGCGGCTTTCCCGTAGGGTCATGGCGGACAAAGGGAGTACGGCGGCCCGCACAGCAGCGGCTCCAGCTCAGGACAGGCCCCAGGAGCCTGAGGTAGTGAGGAGCTATCACCAGCAGGCCTTCCAGTACATCTCTATGGCGCTGCGCATCGACGAGGAGGAGAAAGATCAAAAGGAGCAAGCCATTCAGTGGTACAAGAAGGGTATTGAGGAACTGGAGAAAGGAATAGCTGTAACTATAACTGGCAAAGGTGAACAATATGACAGAGCCCGTCGTTTACAAGCTAAAATGTCAACAAACTTGTTAATGGCAAAGGATCGCTTACAGCTACTAGAAAAAGGGGCTGTTCCCAAAAAAAAAGATCCACCATCGATTTCAAGTAACTCTTATTCTCGTGTAAAGGCTGCTCCTAAGAGCGGGTCATTGGGCAACAGAATACCTAACTGTACTGGTGTATCATCTTCAGCTAGGCAAGCTGGTCCAAATGCACCTTCTAACAGGGGAGCGGCAGGAAAGAACAACACAAGAACAAATAAACCAACAACACCCACTACTGCAGTACGGAAAAAAGACATGAAAAATTTAAGAAATGTAGATAGTAATCTTGCAAACTTGATTTTGAATGAAATTGTGGATAGTGGTCCTACTGTCAAGTTTGCTGACATTGCTGGACAAGATCTAGCCAAGCAAGCCTTGCAGGAGATAGTTATTCTTCCTTCTATACGACCCGAGTTATTTACTGGGCTAAGAGCGCCTGCACGAGGATTGCTGCTGTTTGGTCCTCCAGGGAATGGAAAGACTATGCTGGCAAAAGCTGTTGCTGCTGAATCAAATGCAACATTCTTCAACATAAGTGCAGCGAGTCTGACTTCAAAATATGTGGGAGAAGGTGAAAAGCTGGTGCGTGCACTCTTTTCTGTGGCTAGAGAATTGCAACCTTCCATTATATTTATAGATGAGGTTGATAGTCTTTTATGTGAAAGAAGAGAAGGGGAGCATGATGCAAGCAGAAGACTGAAAACTGAATTTCTAATAGAGTTTGATGGTGTACAATCTGGGGGAGATGACAGAGTTCTTGTTATGGGAGCAACTAACAGACCACAGGAACTTGATGATGCAGTTCTCAGGAGATTCACCAAGAGGGTTTATGTATCTTTACCAAATGAAGAGACTAGACTCTTACTTCTCAAAAATCTTCTGAGTAAACAAGGTAACCCACTTAATGAGAAGGAACTGACTCAGTTATCTAGGCTGACAGAAGGATACTCTGGGAGTGATATAACAGCTTTGGCAAAAGATGCTGCTTTGGGACCAATCAGAGAGTTAAAACCTGAACAAGTCAAAAATATGGCTGCTAGTGAGATGAGAAATATAAAATATTCAGATTTTCTAAGTTCATTAAAGAAGATAAAGTGCAGTGTGAGCCCTTCAACCTTGGAATCTTATATAAGGTGGAATAAGGAATTTGGCGATACTACAGTTTGAAAGACAGACCATCTTATTCAGGGATTAAGCGATGCTGGATGAGATTGTTACGCAGAAATTCACCGCCAAGAAACTTTGCGTATCTTTTGCTTTCAAAACAAAGAAAACTTTAAAAAAAAGCAAACCTCAGATGTGTGCACTAAACTTCTAGAAACTGAATGAGCGAGCAGAAGAAAAGTACTTTATACAAAAAGCTGGCGATATTAACAACTCATGGGGCACTAACTGTAACTTTGAGCGCTTATAACTGCAATTACAGCCTTTGGTTGAAAAGGAACCTTCACACTGTGTGCAAAATTAAGGCTACTCGGAGGAAATGTGGCATATTGGTACTGCTTTCTACCAGTTTGGCTGTGGGAAGACCTGTGCCTTTGCTTTATGTTTCAGGCTTATTTGTGCCTGCCCCTTGTTTGTAATAAATTAATGTTAGACACTCCTTCATACGTACTAATTGCAACTTTTTGTAAATTTATAGAGTTTCTTTAGGGTTGGGTTGGTCAGGGGAAAAGTTGACATGCTTAACGTTAAAGAGTTTTTTATTTCATTATGTGCCAAATGCAAAGACAGAATTGGTTAAAAACGGACTGCCTTACTTGTGCAATAACACCAGTGGTATGGTTTATTAAGGTGACTGAAATCATTTTAGTTTTTCCCTGTAAATGTACTACCAAGAGTAATTTATAGAGTAACCTGGCATAATGATCAAGCACAACTTGCATGCACAGCGGGTCATTTTGTTTCTTTTTTTTTTTCCTTTATTGATGGTGTTAGATCAGTTCTCCTATTAAAAAGCAAGGGTTGGTCAACTGTGAAATAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001093256\|Xenopus laevis spastin (spast), mRNA CCCACGCGTCCGGTGTTATGGCTGTGGGCCCCGTGAATGAATTCTCCGGGCGGAAGAAACGACAAGAAGAAACCGGTCACCCCAGCGGCGGAGACTGGTCCCGGCTCGCCGACGACTCCCCCTTCGACAGAGACGCAGGTCGTGCTCGCCCCGCCCTCACCGCATAAGCGGAACCTTCACCTGTTCTCCTACCCGCTGCTGGCCGTATTCTCCCTGCTGCGCTTCCTGGCCTTTCAGCTGGGGCTGCTTTTCGTCTGGTGTTGTGAACTGCTGTCCCGTAGTGTCATGGCGGACAAAGGACGTACGGTGGCCAGCACAGCAGCGGCTCAGGACAGGCCCCAGGAACCCGAGGTGGTGAGGAGCTATCATCAGCAGGCCTTCCAGTACATCTCTTTGGCCCTGCGCGTTGATGAGGAGGAGAAAGATCAAAAGGAGCAAGCCGTTCAATGGTATAAGAAGGGTATTGAGGAGCTGGAGAAAGGAATAGCTGTACCTATAAGTGGTAAAGGTGAACAATATGACAGAGCCCGTCGTTTACAAGCGAAAATGTCAACAAACTTAATTATGGCAAAAGATCGCTTACAGCTACTAGCAAAGCTGCAAGCAGACATACAAGGTCCGCACTCGCAAATGGAGGTCTGTAGTGACAATACTAACTTACCATGCCGCAATGGACTTCTCAAGCCAGAAAAAGGCGCTGTTCCCAAAAAGAAAGATCCACCACCGATTACAAGTAACTCTTATTCTCGTACAAAGGCACCTCCTAAGAGCGGGTCATTAGGCAACAGGATACCGAATTGTACTTCTGTACCAACTTCAGCTAGGCAAGCTGGTGCACATACACCTTCTAACAGGGGTGCAACCGGAAAGAACAACACAAGAACAAATAAGCCAGCAACACCCACTACTGCAGTACGGAAAAAGGACATGAAAAATTTACGAAATGTAGATAGTAATCTTGCAAATTTGATTTTGAATGAAATTGTGGATAGTGGTCCATCTGTCAAGTTTGCTGACATTGCCGGACAAGATCTAGCCAAACAAGCCTTGCAGGAGATCGTTATTCTTCCTTCTATACGACCCGAGCTATTTACTGGGTTGAGAGCTCCTGCACGAGGATTGCTGCTGTTTGGTCCTCCAGGAAATGGAAAGACTATGCTGGCAAAGGCTGTGGCTGCTGAATCAAATGCAACTTTCTTCAATATAAGTGCAGCAAGTCTGACCTCAAAATATGTGGGAGAAGGTGAAAAGCTAGTACGTGCACTCTTTTCTGTCGCCAGAGAATTGCAACCTTCCATTATTTTCATAGATGAGGTTGATAGTCTTTTATGTGAAAGAAGAGAAGGGGAGCATGATGCAAGCAGACGACTGAAAACAGAGTTTCTAATAGAATTTGATGGTGTACAGTCTGGAGGAGATGACAGAGTTCTTGTTATGGGAGCAACTAACAGACCACAGGAACTAGATGATGCAGTTCTCAGGAGATTCACCAAGAGGGTATATGTAGCTTTACCAAATGAAGAGACTAGACTAGTACTTCTCAAAAATCTTCTGAGTAAACAAGGCAACCCACTGAGTGAGAAGGAACTGACTCAGTTATCTAGGCTGACGGAAGGATACTCTGGGAGCGATATAACAGCTTTGGCAAAAGATGCTGCTTTGGGACCAATCAGAGAGTTAAAACCCGAACAAGTGAAAAATATGGCTGCTAGTGAGATGAGAAATATGAAGTATTCAGATTTCCTGGGTTCATTAAAGAAGATAAAGTGCAGTGTGAGCCATTCAACCCTGGAATCTTACATTCGGTGGAATCAGGACTTTGGTGATACTACTGTTTAAAAGACTAGACTGTTCAACTTATTCAGGGATCAAGCGATGCTGGATGAGATTGTTACAAAGAAATTCACCGCAAAGAGACTTTGCATAAGTTTAGCTTTCAAAACAAAGAAAACTTTAAAAAAAAAGCAAACCTCAGATGTGTGCACTAAACTTCTAGAAACTGAGTAAGCAAGCAGAAGAAAGGTACAAAAAGCCTGTGATATTAACAACTCGTGGGGCACTAACTAACTTTGAGCGCTTATAACTGAAATTACAGCCTTTGGTTCAAAATTAAGTCTACTCGGAAAAACGCGGGATATTGGTATATGCCGTAGAGTTGTTGATCTCTACCAGTTTGGCTATGGGAAGACCTGTGCCTTGGCTTTATGTTTCAGGCTTATTTGTGCCTGCCCCTTGTTTGTAATAAATTAATGTTAGGCACTCCTTCATATGTACTAATTGCAACTTTTTGAAAATTCATAGAGTTTCCTTAGGGTTGGGTGGGGTAGGGTAAAACTGTTGTAGATTTTTTTATTACGTGCCAAGGATTTTCAGATGCACAGAATTGGTTAAACACATAGTGCATTAAGTATGCAAATATGCACAAGTGATGACCCAGGTGGCATGCTTTACTACAGAAATTGAAATCCTTTTAGGTTCTTCCTGTAAATATACTACCAAGAGTAATTCACGGAGTATCCTGACATAATCATAATGCACAGCAGGTCATATATTGCCTGCCTTGATGGTGTTTGTTTTTCTATTAAAAAGTAAGGGTTGGTCAACTGTGATCTGTTTTTATTTTTTTCTCTCTCTATCGAAAAAAATGGCCCTAGAAGATACAAAATATCAGATTTTTCATAATTGTTTTTTTTCCGTAAATCGTACCACAGGACTGTTCTTGAAAAAATCCTTGTGTTTTGTAGCAAGCTAGGATCCAAATCTAACCTGCAGTGAGATTGGAAGGGAACCTTATTCAGTCTCTTTACATTTTTAATATAATTCATTAGATTAGATTTCCGAAGTTGCCTCACGAAGTTCGGGGATATTGTCGCCACGAAGAAGAGGCGATTAGTCGTCAAGTGACTAAATCTCCCCCTATCTTCCTGTGTGCTAAAGCCATTAATAGGATGTTACTGCTCAATAGCAGCCCTTAGTTCTGTCAGCCATCCCAATCCTTATGGTGGCCATACACTGGCAGATTTTGGGCCTGCCAGATCGATATCTTTTTAAAAAAAAAAAAAAAAGACAAAAAAAAAGAAAAAAAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACCTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001016453\|spastin [Xenopus (Silurana) tropicalis] MNSPGGRNDKKKPVTPAAETGPGPPTPPPPPAETQVLLAPPSLHKRNLYLFSYPLLAAFSLLRFLAFQLGLLFVWFCERLSRRVMADKGSTAARTAAAPAQDRPQEPEVVRSYHQQAFQYISMALRIDEEEKDQKEQAIQWYKKGIEELEKGIAVTITGKGEQYDRARRLQAKMSTNLLMAKDRLQLLEKGAVPKKKDPPSISSNSYSRVKAAPKSGSLGNRIPNCTGVSSSARQAGPNAPSNRGAAGKNNTRTNKPTTPTTAVRKKDMKNLRNVDSNLANLILNEIVDSGPTVKFADIAGQDLAKQALQEIVILPSIRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFSVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSGGDDRVLVMGATNRPQELDDAVLRRFTKRVYVSLPNEETRLLLLKNLLSKQGNPLNEKELTQLSRLTEGYSGSDITALAKDAALGPIRELKPEQVKNMAASEMRNIKYSDFLSSLKKIKCSVSPSTLESYIRWNKEFGDTTV UniProtKB	Refseq >NP_001086725\|spastin [Xenopus laevis] MNSPGGRNDKKKPVTPAAETGPGSPTTPPSTETQVVLAPPSPHKRNLHLFSYPLLAVFSLLRFLAFQLGLLFVWCCELLSRSVMADKGRTVASTAAAQDRPQEPEVVRSYHQQAFQYISLALRVDEEEKDQKEQAVQWYKKGIEELEKGIAVPISGKGEQYDRARRLQAKMSTNLIMAKDRLQLLAKLQADIQGPHSQMEVCSDNTNLPCRNGLLKPEKGAVPKKKDPPPITSNSYSRTKAPPKSGSLGNRIPNCTSVPTSARQAGAHTPSNRGATGKNNTRTNKPATPTTAVRKKDMKNLRNVDSNLANLILNEIVDSGPSVKFADIAGQDLAKQALQEIVILPSIRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFSVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSGGDDRVLVMGATNRPQELDDAVLRRFTKRVYVALPNEETRLVLLKNLLSKQGNPLSEKELTQLSRLTEGYSGSDITALAKDAALGPIRELKPEQVKNMAASEMRNMKYSDFLGSLKKIKCSVSHSTLESYIRWNQDFGDTTV UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.10574 [+] Str.44940 Str.54268	Xl.32426 [+] Xl.55459
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	SPAST	OMIM:182601
mouse		MGI	Spast	All(5) Targeted, knock Out(1) Targeted, other(2) Chemically Induced(1)
zebrafish		ZFIN	spast

Publications
First:
Most recent:
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Functional Ontologies
GO: Molecular:		ATP binding nucleoside-triphosphatase activity nucleotide binding
Biological:
Cellular Component:
EC:
KOG:		[O] AAA+-type ATPase (alt_id KOG:0740)

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.10574.1.A1_a_at [+] Str.44940.1.A1_at	Xl.19166.1.A1_at
Affymetrix 2.0			Xl2.55459.1.S1_at [+] Xl2.32426.1.S1_at Xl2.19166.1.A1_at

Symbol legend[+]