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XB-GENEPAGE-948845
Gene Symbol:
xiap
Gene Name: X-linked inhibitor of apoptosis
Synonyms:
api3
,
ilp1
,
miha
,
xlp2
,
birc4
,
xxiap
( Gene Function: Apoptosis inhibitor IAP1 and related BIdomain proteins Protein Function
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Multi-functional protein which regulates not only caspases and apoptosis, but also acts as an E3 ubiquitin-protein ligase mediating ubiquitination and subsequent proteasomal degradation of its target p...[+]
Interactants:
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Diseases: Disease Ontology:
X-linked lymphoproliferative syndrome 1
OMIM:
LYMPHOPROLIFERATIVE SYNDROME, X-LINKED, 2; XLP2
External Links:
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Xenbase Gene ID | XB-GENE-948846 | XB-GENE-948852 | XB-GENE-17342551 | |||||
Gene Symbol | xiap | xiap.L | xiap.S | Chromosome | Chr8 | chr8L | ||
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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CDS |
Gene model
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Gene model
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Entrez Gene |
594971
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733235
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mRNA |
RefSeq
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | xiap | xiap.L | xiap.S | |||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway., EMBO J 1999 |
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Most Recent |
Mcl1 protein levels and Caspase-7 executioner protease control axial organizer cells survival., Dev Dyn 2020 ![]() |
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All | View All Papers 1 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 31 terms | 10 terms | 0 term | |||||
PANTHER | xiap | |||||||
KEGG Pathways | K04725 | K04725 | ||||||
KOG |
[DR] Apoptosis inhibitor IAP1 and related BIdomain proteins
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | xiap | |||||||
ORFs | xiap ORF1 | xiap.L ORF1 | ||||||
Clones | Horizon Source BioScience | Horizon Source BioScience | ||||||
Plasmids | Addgene | Addgene |
Symbol legend:



