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Summary Expression Gene Literature (13) GO Terms (32) Nucleotides (121) Proteins (33) Interactants (150) Wiki
XB-GENEPAGE-948845
Gene Symbol:
xiap

Gene Name:
X-linked inhibitor of apoptosis

Synonyms:
api3 , ilp1 , miha , xlp2 , birc4 , xxiap ( Add synonyms , Nomenclature history )

Gene Function:
Apoptosis inhibitor IAP1 and related BIdomain proteins

Protein Function :
Multi-functional protein which regulates not only caspases and apoptosis, but also acts as an E3 ubiquitin-protein ligase mediating ubiquitination and subsequent proteasomal degradation of its target p...[+]


InterPro :
WAP dom , Anosmin-1 Cys box , Anosmin-1 , FN3 dom [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
X-linked lymphoproliferative syndrome 1 [+]

OMIM:
LYMPHOPROLIFERATIVE SYNDROME, X-LINKED, 2; XLP2 [+]

External Links:
 
Xenbase Gene ID XB-GENE-948846 XB-GENE-948852 XB-GENE-17342551
Gene Symbol xiap xiap.L xiap.S
Chromosome Chr8 chr8L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 594971
733235
mRNA RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine xiap xiap.L xiap.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards XIAP OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Xiap MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Xiap Ensembl
zebrafish
ZFIN, AGR xiap ZFIN Ensembl
chicken
GEISHA BIRC8 Ensembl
fruit fly
worm
Publications
First XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway., EMBO J 1999  
Most Recent Mcl1 protein levels and Caspase-7 executioner protease control axial organizer cells survival., Dev Dyn 2020                
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 31 terms 10 terms 0 term
PANTHER xiap
KEGG Pathways K04725 K04725
KOG [DR] Apoptosis inhibitor IAP1 and related BIdomain proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks xiap
ORFs xiap ORF1 xiap.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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