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Summary Expression Gene Literature (9) GO Terms (9) Nucleotides (79) Proteins (32) Interactants (14) Wiki
XB-GENEPAGE-949108
Gene Symbol:
scnn1b

Gene Name:
sodium channel, non voltage gated 1 beta subunit

Synonyms:
beta-ENaC , besc1 , enacb , scneb , enacbeta , scnn1b-a , scnn1b-b ( Add synonyms , Nomenclature history )

Gene Function:
Non voltage-gated ion channels (DEG/ENaC family)

Protein Function :
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical mem...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
Liddle syndrome [+]

OMIM:
LIDDLE SYNDROME 1; LIDLS1 [+]

External Links:
 
Xenbase Gene ID XB-GENE-949109 XB-GENE-949114 XB-GENE-6252312
Gene Symbol scnn1b scnn1b.L scnn1b.S
Chromosome Chr09 chr9_10L chr9_10S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 779891
378536
397893
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq RefSeq Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine scnn1b scnn1b.L scnn1b.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SCNN1B OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Scnn1b MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Scnn1b Ensembl
zebrafish
chicken
GEISHA SCNN1B Ensembl
fruit fly
worm
Publications
First Alternatively spliced forms of the alpha subunit of the epithelial sodium channel: distinct sites for amiloride binding and channel pore., Mol Pharmacol 1995  
Most Recent The Epithelial Sodium Channel Is a Modifier of the Long-Term Nonprogressive Phenotype Associated with F508del CFTR Mutations., Am J Respir Cell Mol Biol 2017  
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 2 terms 9 terms 5 terms
PANTHER scnn1b
KEGG Pathways K04825 K04825 K04825
KOG [PT] Non voltage-gated ion channels (DEG/ENaC family)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks scnn1b
ORFs scnn1b.L ORF1 scnn1b.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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