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Summary Expression Gene Literature (26) GO Terms (21) Nucleotides (158) Proteins (37) Interactants (13) Wiki
XB-GENEPAGE-950500
Gene Symbol:
ada

Gene Name:
adenosine deaminase

Synonyms:
adenosine deaminase , xada ( Add synonyms , Nomenclature history )

Gene Function:
enzyme catalyzing hydrolysis of adenosine to inosine

Protein Function :
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so...[+]



Interactants:
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Diseases: 


Disease Ontology:
adenosine deaminase deficiency

OMIM:
SEVERE COMBINED IMMUNODEFICIENCY, AUTOSOMAL RECESSIVE, T CELL-NEGATIVE, B CELL-N

External Links:
 
Xenbase Gene ID XB-GENE-950501 XB-GENE-17336388 XB-GENE-950506
Gene Symbol ada ada.L ada.S
Chromosome Chr10 chr9_10L chr9_10S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 496434
108700884
444167
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq Swiss-Prot NCBI Protein RefSeq Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine ada ada.L ada.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ADA OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ada MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Ada Ensembl
zebrafish
ZFIN, AGR ada ZFIN Ensembl
chicken
GEISHA ADA Ensembl
fruit fly
FLYBASE FLYBASE Ada amanda Ensembl
worm
Publications
First Amplification and molecular cloning of murine adenosine deaminase gene sequences., J Biol Chem 1983  
Most Recent Evidence for multiple, distinct ADAR-containing complexes in Xenopus laevis., RNA 2015  
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 20 terms 0 term 10 terms
PANTHER ada
KEGG Pathways K01488 K01488
KOG [F] Adenine deaminase/adenosine deaminase
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks ada
ORFs ada ORF1 ada.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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