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Summary Expression Gene Literature (4) GO Terms (16) Nucleotides (1851) Proteins (46) Interactants (114) Wiki
XB-GENEPAGE-951730
Gene Symbol:
prdx6

Gene Name:
peroxiredoxin 6

Synonyms:
prx6 , aop2 , peroxiredoxin 6 , prx-6 ( Add synonyms , Nomenclature history )

Gene Function:
Alkyl hydroperoxide reductase, thiol specific antioxidant and related enzymes

Protein Function :
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.


InterPro :
MAP65 Ase1 PRC1 , Thioredoxin domain , Peroxiredoxin AhpC-typ , Peroxiredoxin C [+]

Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-951731 XB-GENE-17342196 XB-GENE-6078052
Gene Symbol prdx6 prdx6.L prdx6.S
Chromosome Chr4 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 394706
399434
398641
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine prdx6 prdx6.L prdx6.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PRDX6 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Prdx6 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Prdx6 Ensembl
zebrafish
ZFIN, AGR prdx6 ZFIN Ensembl
chicken
GEISHA PRDX6 Ensembl
fruit fly
worm
Publications
First Peroxiredoxin 6 from the clawed frog Xenopus laevis: cDNA cloning, enzyme characterization, and gene expression during development., Biochemistry (Mosc) 2009  
Most Recent Peroxiredoxin5 Controls Vertebrate Ciliogenesis by Modulating Mitochondrial Reactive Oxygen Species., Antioxid Redox Signal 2019    
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 16 terms 4 terms 4 terms
PANTHER prdx6
KEGG Pathways K11188 K11188 K11188
KOG [O] Alkyl hydroperoxide reductase, thiol specific antioxidant and related enzymes (alt_id KOG:0854)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks prdx6
ORFs prdx6 ORF1 prdx6.L ORF1 prdx6.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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