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XB-GENEPAGE-953739
Gene Symbol:
ncs1
Gene Name: neuronal calcium sensor 1
Synonyms:
xfreq
,
flup
,
freq
,
frequenin
,
ncs-1
( Gene Function: Ca2+ sensor (EF-Hand superfamily) Protein Function
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Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin.
Interactants:
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Diseases: External Links:
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Xenbase Gene ID | XB-GENE-953740 | XB-GENE-953746 | XB-GENE-17342716 | |||||
Gene Symbol | ncs1 | ncs1.L | ncs1.S | Chromosome | Chr8 | Scaffold46 | chr8S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
394570
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399297
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432213
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mRNA |
RefSeq
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | ncs1 | ncs1.L | ncs1.S | |||||
Orthology |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Molecular cloning and functional characterization of the Xenopus Ca(2+)-binding protein frequenin., Proc Natl Acad Sci U S A 1995 ![]() |
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Most Recent |
PLC and IP3-evoked Ca2+ release initiate the fast block to polyspermy in Xenopus laevis eggs., J Gen Physiol 2018 ![]() |
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All | View All Papers | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 13 terms | 9 terms | 1 terms | |||||
PANTHER | ncs1 | |||||||
KEGG Pathways | K19932 | K19932 | K19932 | |||||
KOG |
[T] Ca2+ sensor (EF-Hand superfamily)
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | ncs1 | |||||||
ORFs | ncs1 ORF1 | ncs1.L ORF1 | ncs1.S ORF1 | |||||
Clones | Horizon Source BioScience | Horizon Source BioScience | Horizon | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



