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Summary Expression Gene Literature (22) GO Terms (7) Nucleotides (289) Proteins (35) Interactants (304) Wiki
XB-GENEPAGE- 956214

Gene Symbol: ezh2

Gene Name: enhancer of zeste 2 polycomb repressive complex 2 subunit

Synonyms: enx1 , ezh1 , kmt6 , enx-1 , xez , xtezh2 , ezh2-a , ezh2-b
Add Xenopus synonyms , Nomenclature history


Gene Function: Transcriptional repressor EZH1

Protein Function:
Polycomb group (PcG) protein. Catalytic subunit of the prc2/eed-ezh2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. May...[+]


Interactants: YYY

OMIM Disease Associations: WEAVER SYNDROME; WVS
1/8
 
Xenbase Gene ID XB-GENE-956215 XB-GENE-956220 XB-GENE-6252001
Gene Symbol ezh2 ezh2.L ezh2.S
Chromosome scaffold_6 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2
Entrez Gene
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.1297 Xl.19136 [+] Xl.85841 Xl.47646
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 11 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine ezh2 ezh2.L ezh2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards EZH2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Ezh2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ezh2 ZFIN Ensembl
chicken
GEISHA EZH2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: The polycomb group protein EED interacts with YY1, and both proteins induce neural tissue in Xenopus embryos. [Mol Cell Biol 2001]
Most recent: Specification of anteroposterior axis by combinatorial signaling during Xenopus development. [Wiley Interdiscip Rev Dev Biol 2016]
View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 7 terms 7 terms
EC
PANTHER ezh2
KEGG Pathways K11430 K11430 K11430
KOG [K] Transcriptional repressor EZH1
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Antibody Ezh2 Ab1 Ezh2 Ab1 Ezh2 Ab1
Morpholino ezh2 MO1 , ezh2 MO2 ezh2 MO1 , ezh2 MO2 ezh2 MO1 , ezh2 MO2
ORF MGC114646 ORF1
Affymetrix 1.0 StrJgi.3836.1.S1_at [+] Xl.19136.1.S1_at
Affymetrix 2.0 Xl2.19136.1.S1_a_at [+] Xl2.47646.1.S1_at

Symbol legend[+]

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