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Summary Expression Gene Literature (22) GO Terms (3) Nucleotides (355) Proteins (35) Interactants (114) Wiki
XB-GENEPAGE-957400
Gene Symbol: pum1

Gene Name: pumilio RNA binding family member 1

Synonyms: pumh , pumilio , pumilio 1 , pumilio-1 , pumh1 , puml1 , pumilio1 ( Add synonyms , Nomenclature history )

Gene Function: Translational repressor Pumilio/PUF3 and related RNA-binding proteins (Puf superfamily)

Protein Function :
Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGU...[+]

Interactants: Loading ...
OMIM Diseases: SPINOCEREBELLAR ATAXIA 47; SCA47

 
Xenbase Gene ID XB-GENE-957401 XB-GENE-17346314 XB-GENE-957405
Gene Symbol pum1 pum1.L pum1.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide NCBI Nucleotide RefSeq
Protein NCBI Protein TrEMBL NCBI Protein TrEMBL TrEMBL RefSeq TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine pum1 pum1.L pum1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards PUM1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Pum1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR pum1 ZFIN Ensembl
chicken
GEISHA PUM1 Ensembl
fruit fly
worm
WORMBASE
Publications
First Biochemical identification of Xenopus Pumilio as a sequence-specific cyclin B1 mRNA-binding protein that physically interacts with a Nanos homolog, Xcat-2, and a cytoplasmic polyadenylation element-binding protein., J Biol Chem 2001  
Most Recent The translational functions of embryonic poly(A)-binding protein during gametogenesis and early embryo development., Mol Reprod Dev 2019            
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 1 terms 1 terms 3 terms
PANTHER pum1
KEGG Pathways K17943
KOG [J] Translational repressor Pumilio/PUF3 and related RNA-binding proteins (Puf superfamily)
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Antibody Pum1 Ab1 , Pum1 Ab2 , Pum1 Ab3 Pum1 Ab1 , Pum1 Ab2 , Pum1 Ab3
ORF pum1.S ORF1
Affymetrix 1.0 StrAffx.40.1.S1_s_at [+] Xl.11086.1.S1_at [+]
Affymetrix 2.0 Xl2.11086.1.S1_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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