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Summary Expression Gene Literature (18) GO Terms (8) Nucleotides (350) Proteins (56) Interactants (227) Wiki
XB-GENEPAGE-957447
Gene Symbol:
impdh1

Gene Name:
IMP (inosine 5'-monophosphate) dehydrogenase 1

Synonyms:
imp1 , imp , imp2 ( Add synonyms , Nomenclature history )

Gene Function:
IMP dehydrogenase/GMP reductase

Protein Function :
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays ...[+]



Interactants:
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Diseases: 


Disease Ontology:
retinitis pigmentosa 10

OMIM:
RETINITIS PIGMENTOSA 10; RP10 [+]

External Links:
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Xenbase Gene ID XB-GENE-957448 XB-GENE-957455 XB-GENE-17333984
Gene Symbol impdh1 impdh1.L impdh1.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.1
CDS Gene model Gene model
Entrez Gene 550037
380485
mRNA RefSeq RefSeq
Protein RefSeq RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine impdh1 impdh1.L impdh1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards IMPDH1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Impdh1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Impdh1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR impdh1a impdh1b ZFIN Ensembl
chicken
fruit fly
worm
Publications
First The plasma-membrance IMP pattern as related to animal/vegetal polarity in the amphibian egg., Dev Biol 1978  
Most Recent Conservatism and variability of gene expression profiles among homeologous transcription factors in Xenopus laevis., Dev Biol 2017                            
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 6 terms 0 term
PANTHER impdh1
KEGG Pathways K00088 K00088
KOG [F] IMP dehydrogenase/GMP reductase
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks impdh1
Clones Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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